{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T19:52:33Z","timestamp":1792785153298,"version":"4.5.0"},"reference-count":29,"publisher":"Georg Thieme Verlag KG","issue":"12","funder":[{"name":"JSPS KAKENHI","award":["23K08455"],"award-info":[{"award-number":["23K08455"]}]},{"DOI":"10.13039\/100016170","name":"Japan Blood Products Organization","doi-asserted-by":"crossref","award":["2024"],"award-info":[{"award-number":["2024"]}],"id":[{"id":"10.13039\/100016170","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Thromb Haemost"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>The criteria for diagnosing sepsis-induced coagulopathy (SIC) may overlap with those of Japanese Association for Acute Medicine (JAAM) disseminated intravascular coagulation (DIC). This study determined if the diagnostic criteria of SIC overlap with JAAM DIC diagnostic criteria for identifying patients with DIC according to the International Society on Thrombosis and Haemostasis (ISTH) criteria and whether the patients diagnosed with these criteria have the same prognosis.<\/jats:p>\n                  <jats:p>This multicenter retrospective study included patients with sepsis diagnosed using the JAAM and ISTH DIC and SIC criteria on days 1 and 4. The established ISTH DIC criteria was the reference standard for primary outcome that compared the characteristics of SIC and JAAM DIC. Secondary outcomes were multiple organ dysfunction syndrome (MODS), ventilator-free and intensive care unit\u2013free days, and in-hospital mortality.<\/jats:p>\n                  <jats:p>A total of 1,438 patients were included in this study. On day 1, the JAAM DIC and SIC criteria diagnosed almost all patients with ISTH DIC (98 and 94%, respectively), predicting ISTH DIC (area under the receiver operating curve [AUC]: 0.740 versus 0.752, p\u2009=\u20090.523) and MODS (AUC: 0.686 versus 0.697, p\u2009=\u20090.546) on day 4 and progressing to ISTH DIC in the same proportion (28.6 versus 30.1%, p\u2009=\u20090.622). There were no differences in survival probabilities (p\u2009=\u20090.196) or secondary outcomes between patients diagnosed using JAAM DIC and SIC criteria on day 1.<\/jats:p>\n                  <jats:p>SIC and JAAM DIC diagnoses were equal among patients with sepsis, suggesting that SIC criteria add little to current DIC scoring systems.<\/jats:p>","DOI":"10.1055\/a-2530-7553","type":"journal-article","created":{"date-parts":[[2025,2,3]],"date-time":"2025-02-03T18:59:51Z","timestamp":1738609191000},"page":"1240-1248","source":"Crossref","is-referenced-by-count":7,"title":["Utility of Sepsis-induced Coagulopathy Among Disseminated Intravascular Coagulation Diagnostic Criteria: A Multicenter Retrospective Validation Study"],"prefix":"10.1055","volume":"125","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3525-0750","authenticated-orcid":false,"given":"Satoshi","family":"Gando","sequence":"additional","affiliation":[{"name":"Division of Acute and Critical Care Medicine, Department of Anesthesiology and Critical Care Medicine, Hokkaido University Faculty of Medicine, Sapporo, Japan"},{"name":"Department of Acute and Critical Care Medicine, Sapporo Higashi Tokushukai Hospital, Sapporo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5220-3342","authenticated-orcid":false,"given":"Takeshi","family":"Wada","sequence":"additional","affiliation":[{"name":"Division of Acute and Critical Care Medicine, Department of Anesthesiology and Critical Care Medicine, Hokkaido University Faculty of Medicine, Sapporo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazuma","family":"Yamakawa","sequence":"additional","affiliation":[{"name":"Department of Emergency and Critical Care Medicine, Osaka Medical and Pharmaceutical University, Takatsuki, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshikazu","family":"Abe","sequence":"additional","affiliation":[{"name":"Department of Emergency and Critical Care Medicine, Tsukuba Memorial Hospital, Tsukuba, Japan"},{"name":"Health Services Research and Development Center, University of Tsukuba, Tsukuba, Japan"},{"name":"Department of Health Services Research, Faculty of Medicine, University of Tsukuba, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seitaro","family":"Fujishima","sequence":"additional","affiliation":[{"name":"Center for Preventive Medicine, Keio University School of Medicine, Tokyo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shigeki","family":"Kushimoto","sequence":"additional","affiliation":[{"name":"Division of Emergency and Critical Care Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshihiko","family":"Mayumi","sequence":"additional","affiliation":[{"name":"Department of Intensive Care Unit, Japan Community Healthcare Organization Chukyo Hospital, Nagoya, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroshi","family":"Ogura","sequence":"additional","affiliation":[{"name":"Department of Traumatology and Acute Critical Medicine, Osaka University Graduate School of Medicine, Suita, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daizoh","family":"Saitoh","sequence":"additional","affiliation":[{"name":"Graduate School of Emergency Medical System, Kokushikan University, Tokyo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atsushi","family":"Shiraishi","sequence":"additional","affiliation":[{"name":"Emergency and Trauma Center, Kameda Medical Center, Kamogawa, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yutaka","family":"Umemura","sequence":"additional","affiliation":[{"name":"Devision of Trauma and Surgical Critical Care, Osaka General Medical Center, Osaka, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasuhiro","family":"Otomo","sequence":"additional","affiliation":[{"name":"National Hospital Organization (NHO) Disaster Medical Center, Tokyo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"on behalf of the Japanese Association for Acute Medicine (JAAM)","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2025,2,27]]},"reference":[{"issue":"05","key":"ref1","doi-asserted-by":"crossref","first-page":"1327","DOI":"10.1055\/s-0037-1616068","article-title":"Towards definition, clinical and laboratory criteria, and a scoring system for disseminated intravascular coagulation","volume":"86","author":"F B Taylor Jr","year":"2001","journal-title":"Thromb Haemost"},{"issue":"12","key":"ref2","doi-asserted-by":"crossref","first-page":"2416","DOI":"10.1097\/01.CCM.0000147769.07699.E3","article-title":"Prospective 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sepsis","volume":"119","author":"K Yamakawa","year":"2019","journal-title":"Thromb Haemost"},{"issue":"01","key":"ref28","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1186\/s13613-020-00704-5","article-title":"Performances of disseminated intravascular coagulation scoring systems in septic shock patients","volume":"10","author":"J Helms","year":"2020","journal-title":"Ann Intensive Care"},{"issue":"03","key":"ref29","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1093\/labmed\/lmac112","article-title":"Validation of two revised, simplified criteria for assessing sepsis-associated disseminated intravascular coagulation in ICU patients with sepsis-3: a retrospective study","volume":"54","author":"B Wang","year":"2023","journal-title":"Lab Med"}],"container-title":["Thrombosis and 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