{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T10:52:00Z","timestamp":1783075920313,"version":"3.54.6"},"reference-count":22,"publisher":"Georg Thieme Verlag KG","issue":"01","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Zentralbl Chir"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title>\n                  <jats:p>Die einseitige perioperative Stimmlippenparese (eSLP) bei thoraxchirurgischen\n\t\t\t\tOperationen birgt f\u00fcr die betroffenen Patienten die Gefahr von klinisch relevanten\n\t\t\t\tKomplikationen infolge stimmfunktioneller Einschr\u00e4nkungen. Neben der konservativen\n\t\t\t\tStimmtherapie (Logop\u00e4die) bietet die Stimmlippenaugmentation (SLA) eine\n\t\t\t\tinterventionelle Therapieoption. Indikation und Wahl des Zeitpunktes werden nicht\n\t\t\t\teinheitlich gehandhabt und bed\u00fcrfen phoniatrisch-phonochirurgischer\n\t\t\t\tExpertise.<\/jats:p>\n                  <jats:p>In einer retrospektiven Studie wurden Patienten mit der Erstdiagnose einer eSLP\n\t\t\t\tvor oder nach einer thoraxchirurgischen Operation in kurativer Behandlungsintention\n\t\t\t\tim Zeitraum 01\/2010 bis 12\/2020 analysiert. Als prim\u00e4rer Endpunkt wurde der\n\t\t\t\tZeitpunkt der SLA inkl. des Augmentationsergebnisses definiert. Sekund\u00e4re Endpunkte\n\t\t\t\twaren das Auftreten der eSLP, die Indikation zur SLA und m\u00f6gliche\n\t\t\t\tKomplikationen.<\/jats:p>\n                  <jats:p>Von insgesamt n\u00a0=\u00a0939 eingeschlossenen F\u00e4llen wurde bei n\u00a0=\u00a044 (4,7%) Patienten\n\t\t\t\teine eSLP dokumentiert. Es erfolgte die Differenzierung nach der Tumorentit\u00e4t:\n\t\t\t\tLungenkarzinom n\u00a0=\u00a021 (47,7%), Lungenmetastasen n\u00a0=\u00a08 (18,2%), Mediastinaltumor\n\t\t\t\tn\u00a0=\u00a013 (29,5%) und malignes Pleuramesotheliom n\u00a0=\u00a02 (4,6%). W\u00e4hrend bei n\u00a0=\u00a015\n\t\t\t\tPatienten die SLP bereits pr\u00e4operativ bestand, trat in 66% der F\u00e4lle (n\u00a0=\u00a029) eine\n\t\t\t\tpostoperative SLP auf. Eine Fr\u00fchst-SLA mit Hyalurons\u00e4ure erfolgte bei n\u00a0=\u00a016 (36,4%)\n\t\t\t\tPatienten bereits in den ersten postoperativen Tagen. Die Indikation zur SLA wurde\n\t\t\t\tbei Stimmlippenparesen in Paramedian- (56%) oder Intermedi\u00e4rstellung (31%) mit einer\n\t\t\t\tausgepr\u00e4gten Glottisschluss-Insuffizienz (100%) und klinisch hochgradiger Heiserkeit\n\t\t\t\t(93,6%) gestellt. Mit der durchgef\u00fchrten Intervention lie\u00df sich in allen F\u00e4llen eine\n\t\t\t\tMedialisierung der paretischen Stimmlippe und damit ein verbesserter Glottisschluss\n\t\t\t\terreichen. Hierdurch kam es zu einer Verbesserung von Stimmklang und\n\t\t\t\tHustensto\u00df.<\/jats:p>\n                  <jats:p>Eine eSLP trat in der Thoraxchirurgie in 4,7% der F\u00e4lle auf und wurde in 36% der\n\t\t\t\tF\u00e4lle noch w\u00e4hrend des station\u00e4ren Aufenthalts mittels komplikationsloser SLA\n\t\t\t\terfolgreich behandelt. Eine eSLP sollte fr\u00fchzeitig abgekl\u00e4rt und bei entsprechender\n\t\t\t\tIndikation zeitnah f\u00fcr eine Fr\u00fchst-SLA evaluiert werden.<\/jats:p>","DOI":"10.1055\/a-2539-5610","type":"journal-article","created":{"date-parts":[[2025,4,28]],"date-time":"2025-04-28T18:38:17Z","timestamp":1745865497000},"page":"103-109","source":"Crossref","is-referenced-by-count":1,"title":["Behandlung der perioperativen einseitigen Stimmlippenparese bei thoraxchirurgischen Eingriffen: Stellenwert der Fr\u00fchst-Stimmlippenaugmentation"],"prefix":"10.1055","volume":"151","author":[{"given":"Elena","family":"Loch","sequence":"additional","affiliation":[{"name":"Abteilung f\u00fcr Thoraxchirurgie, University Hospital Regensburg, Regensburg, Deutschland"},{"name":"Allgemein-, Viszeral- und Thoraxchirurgie, Klinikum N\u00fcrnberg, Standort Nord, N\u00fcrnberg, Deutschland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jose Carmelo 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