{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T08:05:04Z","timestamp":1788595504438,"version":"build-2803163510"},"reference-count":33,"publisher":"Georg Thieme Verlag KG","issue":"09","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Reconstr Microsurg"],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>To investigate the risk factors for plate exposure in primary oral cancer patients with mandibular defects undergoing tumor ablation followed by vascularized free fibular flap (FFF) transfer, we conducted a retrospective observational study in a single institution in Taiwan.<\/jats:p><jats:p>The study was performed on a total of 292 primary oral cancer patients who underwent FFF reconstruction between 2015 and 2019. A variety of clinicopathological, surgical, and postoperative parameters were identified and assessed. The data were statistically analyzed with univariate and multivariate logistic regression, and the probability of plate exposure-free rate was plotted as Kaplan-Meier survival curve.<\/jats:p><jats:p>The overall plate exposure rate was 28.76%. The re-exploration group had a higher rate of plate exposure than patients without re-exploration (12.2% vs. 5%, p\u2009&lt;\u20090.05). The 3-year probability of plate exposure-free rates in patients with (n\u2009=\u2009216) and without (n\u2009=\u200976) postoperative radiotherapy were 65.9 and 92.5%, and in patients with (n\u2009=\u2009141) and without (n\u2009=\u2009151) postoperative wound infection were 55.3 and 91.2%, respectively. The multivariate logistic regression showed postoperative radiotherapy and wound infection were independent risk factors for developing plate exposure (adjusted odds ratio [95% CI]: 3.73 [1.37\u201310.68] and 10.71 [5.15\u201322.26], p\u2009=\u20090.01 and p &lt;0.001, respectively). More patients required surgical intervention to manage the exposure of hardware.<\/jats:p><jats:p>Our study has highlighted that postoperative radiotherapy and postoperative wound infection are independent risk factors for plate exposure.<\/jats:p>","DOI":"10.1055\/a-2540-0737","type":"journal-article","created":{"date-parts":[[2025,2,17]],"date-time":"2025-02-17T19:20:31Z","timestamp":1739820031000},"page":"802-809","source":"Crossref","is-referenced-by-count":3,"title":["Risk of Plate Exposure in Vascularized Fibula Flap for Mandibular Reconstruction in Primary Oral Cancers"],"prefix":"10.1055","volume":"41","author":[{"given":"Ashwin Alke","family":"Pai","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery, Chang Gung Memorial Hospital & Chang Gung University College of Medicine, Taoyuan, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angela Chien-Yu","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery, Chang Gung Memorial Hospital & Chang Gung University College of Medicine, Taoyuan, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2646-0358","authenticated-orcid":false,"given":"Charles Yuen Yung","family":"Loh","sequence":"additional","affiliation":[{"name":"St Andrew's Centre for Plastic and Reconstructive Surgery, Broomfield Hospital, Court Road, Chelmsford, Essex, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shao-Yu","family":"Hung","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery, Chang Gung Memorial Hospital & Chang Gung University College of Medicine, Taoyuan, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3995-5894","authenticated-orcid":false,"given":"Chung-Kan","family":"Tsao","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery, Chang Gung Memorial Hospital & Chang Gung University College of Medicine, Taoyuan, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huang-Kai","family":"Kao","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery, Chang Gung Memorial Hospital & Chang Gung University College of Medicine, Taoyuan, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2025,3,7]]},"reference":[{"issue":"03","key":"ref1","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1097\/00006534-199903000-00009","article-title":"Free fibula osteoseptocutaneous-pedicled pectoralis major myocutaneous flap combination in 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