{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T22:03:54Z","timestamp":1790633034861,"version":"4.1.0"},"reference-count":25,"publisher":"Georg Thieme Verlag KG","issue":"05","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ultraschall Med"],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The aim of this systematic review was to investigate the outcomes of pregnancies with fetal cerebral lateral ventricle asymmetry without dilation. We conducted a comprehensive literature search in the Embase, Medline, and Web of Science databases until April 29, 2024, of observational cohort studies that reported fetal ventricular asymmetry without dilation detected on ultrasound or magnetic resonance imaging. Of the 150 studies identified, 6 met the inclusion criteria. Among the cases of non-dilated ventricular asymmetry, 36.8\u201346.2% progressed to ventriculomegaly on follow-up by neurosonography or magnetic resonance imaging. Additional findings in the central nervous system were observed in 5.5\u201310.5% of cases, while 7.6% had additional fetal body findings. Abnormal genetic findings were present in 5.1% of cases. Postnatal follow-up indicated no abnormal developmental findings during the first year of life. By the age of 9\u201311 years, lower writing speed was observed, yet verbal fluency scores were higher than in the general population. In conclusion, non-dilated ventricular asymmetry in fetuses showed the potential for progression to ventriculomegaly, and linkage to genetic abnormalities. Larger prospective studies are essential to fully elucidate the condition\u2019s natural history and refine clinical management strategies.<\/jats:p>","DOI":"10.1055\/a-2548-6131","type":"journal-article","created":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T18:56:52Z","timestamp":1745434612000},"page":"483-491","source":"Crossref","is-referenced-by-count":2,"title":["Fetal Cerebral Ventricular Asymmetry Without Dilation: A Systematic Review"],"prefix":"10.1055","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5270-8436","authenticated-orcid":false,"given":"Inshirah","family":"Sgayer","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Galilee Medical Center, Nahariya, Israel"},{"name":"Azrieli Faculty of Medicine, Bar Ilan University, Safed, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nizar","family":"Khatib","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Rambam Health Care Campus, Haifa, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lior","family":"Lowenstein","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Galilee Medical Center, Nahariya, Israel"},{"name":"Azrieli Faculty of Medicine, Bar Ilan University, Safed, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marwan","family":"Odeh","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Galilee Medical Center, Nahariya, Israel"},{"name":"Azrieli Faculty of Medicine, Bar Ilan University, Safed, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2025,4,23]]},"reference":[{"issue":"04","key":"ref1","doi-asserted-by":"publisher","first-page":"359.e1","DOI":"10.1016\/j.ajog.2009.11.001","article-title":"Fetal brain asymmetry: in utero sonographic study of normal fetuses","volume":"202","author":"Z Kivilevitch","year":"2010","journal-title":"Am J Obstet Gynecol"},{"issue":"02","key":"ref2","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1002\/uog.19038","article-title":"Outcome of fetuses with prenatal diagnosis of isolated severe bilateral ventriculomegaly: systematic review and meta-analysis [published correction appears in Ultrasound Obstet Gynecol. 2018 Nov;52(5):684]","volume":"52","author":"S Carta","year":"2018","journal-title":"Ultrasound Obstet Gynecol"},{"issue":"04","key":"ref3","doi-asserted-by":"publisher","first-page":"566","DOI":"10.3174\/ajnr.A6456","article-title":"The Lateral Ventricles: A Detailed Review of Anatomy, Development, and Anatomic Variations","volume":"41","author":"CL Scelsi","year":"2020","journal-title":"AJNR Am J Neuroradiol"},{"issue":"03","key":"ref4","doi-asserted-by":"publisher","first-page":"476","DOI":"10.1002\/uog.22145","article-title":"ISUOG Practice Guidelines (updated): sonographic examination of the fetal central nervous system. 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