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Minimalinvasive Verfahren r\u00fccken zunehmend in den Fokus, da chirurgische Resektionen wegen funktioneller und \u00e4sthetischer Risiken nur selten indiziert sind.<\/jats:p>\n                  <jats:p>Mit OVAMA steht erstmals ein international validiertes Instrument zur Verf\u00fcgung, das die Symptomlast bei Gef\u00e4\u00dfmalformationen standardisiert und patientenorientiert erfasst. In Kombination mit PROMIS-Skalen erm\u00f6glicht es eine umfassendere Beurteilung von Krankheitsauswirkungen und Lebensqualit\u00e4t. Dadurch k\u00f6nnen Therapien gezielter geplant, individuelle Belastungen besser erkannt und der Behandlungserfolg objektiver bewertet werden.<\/jats:p>","DOI":"10.1055\/a-2559-4947","type":"journal-article","created":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T23:30:25Z","timestamp":1773099025000},"page":"251-257","source":"Crossref","is-referenced-by-count":0,"title":["Update zu vaskul\u00e4ren Malformationen: Von der Patientenperspektive zu modernen Behandlungsmethoden"],"prefix":"10.1055","volume":"151","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7108-418X","authenticated-orcid":false,"given":"Aleksandra","family":"Tuleja","sequence":"additional","affiliation":[{"name":"Division of Angiology, Swiss Cardiovascular Center, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland"},{"name":"Graduate School for Health Sciences, University of Bern, Bern, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2026,3,9]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"657","DOI":"10.1007\/s40257-020-00528-w","article-title":"New and Emerging Targeted Therapies for Vascular Malformations","volume":"21","author":"A Van Damme","year":"2020","journal-title":"Am J Clin Dermatol"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"318","DOI":"10.1016\/j.jvs.2019.06.217","article-title":"Efficacy and safety of sirolimus in the treatment of vascular anomalies: A systematic review","volume":"71","author":"C Freixo","year":"2020","journal-title":"J Vasc Surg"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"10499","DOI":"10.1038\/s41598-023-37468-4","article-title":"Targeted treatment of severe vascular malformations harboring PIK3CA and TEK mutations with alpelisib is highly effective with limited toxicity","volume":"13","author":"M Sterba","year":"2023","journal-title":"Sci Rep"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1056\/NEJMoa2309160","article-title":"Sotorasib for Vascular Malformations Associated with KRAS G12C Mutation","volume":"391","author":"A Fraissenon","year":"2024","journal-title":"N Engl J Med"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"158","DOI":"10.1053\/j.sempedsurg.2014.06.016","article-title":"ISSVA classification","volume":"23","author":"R Dasgupta","year":"2014","journal-title":"Semin Pediatr Surg"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"598","DOI":"10.21037\/cdt-24-529","article-title":"Alcohol embolization versus non-invasive treatment for pain relief in peripheral venous malformations: a comparative study","volume":"15","author":"A Tuleja","year":"2025","journal-title":"Cardiovasc Diagn Ther"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"1514","DOI":"10.1097\/DSS.0000000000002389","article-title":"Effectiveness and Safety of Ethanol for the Treatment of Venous Malformations: A Meta-Analysis","volume":"46","author":"Y Sun","year":"2020","journal-title":"Dermatol Surg"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"4","DOI":"10.5469\/neuroint.2019.00213","article-title":"Sclerotherapy for Venous Malformations of Head and Neck: Systematic Review and Meta-Analysis","volume":"15","author":"L De Maria","year":"2020","journal-title":"Neurointervention"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"6425","DOI":"10.1007\/s00330-024-10723-6","article-title":"Outcome of bleomycin electrosclerotherapy of slow-flow malformations in adults and children","volume":"34","author":"VF Schmidt","year":"2024","journal-title":"Eur Radiol"},{"key":"ref10","first-page":"977","article-title":"Effectiveness of sclerotherapy, surgery, and laser therapy in patients with venous malformations: a systematic review","volume":"37","author":"CJ der Vleuten","year":"2014","journal-title":"Cardiovasc Intervent Radiol"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s11136-019-02301-x","article-title":"Outcome measurement instruments for peripheral vascular malformations and an assessment of the measurement properties: a systematic review","volume":"29","author":"SER Horbach","year":"2020","journal-title":"Qual Life Res"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"1054","DOI":"10.1016\/j.jvs.2021.08.101","article-title":"Clinical characteristics associated with pain in patients with peripheral vascular malformations","volume":"75","author":"MLE Stor","year":"2022","journal-title":"J Vasc Surg"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"1034","DOI":"10.1016\/j.jvsv.2023.03.012","article-title":"Clinical phenotype of adolescent and adult patients with extracranial vascular malformation","volume":"11","author":"A Tuleja","year":"2023","journal-title":"J Vasc Surg Venous Lymphat Disord"}],"container-title":["DMW - 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