{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T18:01:11Z","timestamp":1781632871317,"version":"3.54.5"},"reference-count":19,"publisher":"Georg Thieme Verlag KG","issue":"05","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Aktuelle Urol"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>Die anatomische Enukleation der Prostata (AEEP) ist eine Behandlungsoption f\u00fcr die Behandlung der benignen Prostatahyperplasie, unabh\u00e4ngig von der Gr\u00f6\u00dfe der Prostata. W\u00e4hrend Fortschritte in der Lasertechnologie zu klinischen Verbesserungen in der Enukleationsphase gef\u00fchrt haben, wurde der Morcellationsprozess wenig weiterentwickelt, sodass es wenige Innovationen bei Morcellationsger\u00e4ten gab. Ziel dieser Studie war es, die Effizienz zwischen 2 Morcellatoren in einem Ex-vivo-Modell zu vergleichen: dem Piranha (Richard Wolf GmbH, Knittlingen) und einem neu eingef\u00fchrten, noch nicht kommerziell erh\u00e4ltlichen Morcellator, dem ActiveCut (Active Fiber Systems GmbH, Jena).<\/jats:p><jats:p>Die 2 Morcellatoren wurden in einem neu entwickelten Ex-vivo-Modell getestet. In beiden Gruppen wurden wiederverwendbare Messerklingen je 10-mal bei vergleichbaren Geschwindigkeitseinstellungen getestet. Bei jeder Morcellation wurden 60 g rohes Rinderherz morcelliert. Anschlie\u00dfend wurde die Effizienz der Morcellation verglichen. Endpunkte waren die Morcellationseffizienz (g\/min) und die Evaluation eines m\u00f6glichen Verschlei\u00dfes der Messer \u00fcber die Versuche hinweg. Die Mittelwerte kontinuierlicher Variablen wurden unter Verwendung des t-Tests mit Standardabweichung verglichen.<\/jats:p><jats:p>Insgesamt wurden 10 aufeinanderfolgende Morcellationen mit jedem Morcellatorsystem durchgef\u00fchrt. Der ActiveCut zeigte h\u00f6here Morcellationsraten mit 12,43 g\/min im Vergleich zum Piranha mit 7,09 g\/min (p&lt;0,05). Allerdings zeigte der ActiveCut-Morcellator \u00fcber 10 Versuche hinweg abnehmende Morcellationsraten. In 2 F\u00e4llen musste Gewebe w\u00e4hrend der Morcellation aus der Klingenkupplung entfernt werden, w\u00e4hrend der Piranha-Morcellator konstante Morcellationsraten ohne Fehlfunktion aufwies.<\/jats:p><jats:p>In dieser Ex-vivo-Studie, die den ActiveCut- und den Piranha-Morcellator vergleicht, zeigte der ActiveCut eine h\u00f6here Morcellationseffizienz. Allerdings wurde der ActiveCut bisher noch nicht klinisch getestet; in zuk\u00fcnftigen klinischen Studien m\u00fcssen daher sowohl die Sicherheit als auch m\u00f6gliche Fehlfunktionen sorgf\u00e4ltig gepr\u00fcft werden.<\/jats:p>","DOI":"10.1055\/a-2560-3827","type":"journal-article","created":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T18:58:28Z","timestamp":1745434708000},"page":"433-438","source":"Crossref","is-referenced-by-count":1,"title":["Ex-vivo-Vergleichsstudie zur Morcellationseffizienz unterschiedlicher Morcellatoren"],"prefix":"10.1055","volume":"56","author":[{"given":"Benedikt","family":"Becker","sequence":"additional","affiliation":[{"name":"Abteilung f\u00fcr Urologie, Asklepios Klinik Barmbek, Hamburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher","family":"Netsch","sequence":"additional","affiliation":[{"name":"Abteilung f\u00fcr Urologie, Asklepios Klinik Barmbek, Hamburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas J.","family":"Gross","sequence":"additional","affiliation":[{"name":"Abteilung f\u00fcr Urologie, Asklepios Klinik Barmbek, Hamburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clemens","family":"Rosenbaum","sequence":"additional","affiliation":[{"name":"Abteilung f\u00fcr Urologie, Asklepios Klinik Barmbek, Hamburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1112-0705","authenticated-orcid":false,"given":"Friedrich Otto","family":"Hartung","sequence":"additional","affiliation":[{"name":"Universit\u00e4tsklinikum Mannheim, Klinik f\u00fcr Urologie und Urochirurgie, Mannheim, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon","family":"Filmar","sequence":"additional","affiliation":[{"name":"Abteilung f\u00fcr Urologie, Asklepios Klinik Barmbek, Hamburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sophia","family":"Hook","sequence":"additional","affiliation":[{"name":"Abteilung f\u00fcr Urologie, Asklepios Klinik Barmbek, Hamburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2025,4,23]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"207","DOI":"10.1055\/a-2286-1243","article-title":"Development of endoscopic enucleation of the prostate","volume":"55","author":"AJ Gross","year":"2024","journal-title":"Aktuelle Urol"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"l5919","DOI":"10.1136\/bmj.l5919","article-title":"Comparative efficacy and safety of new surgical treatments for benign prostatic hyperplasia: systematic review and network meta-analysis","volume":"367","author":"S-W 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