{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T15:09:10Z","timestamp":1783523350317,"version":"3.55.0"},"reference-count":13,"publisher":"Georg Thieme Verlag KG","issue":"02","license":[{"start":{"date-parts":[[2025,3,19]],"date-time":"2025-03-19T00:00:00Z","timestamp":1742342400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["AJP Rep"],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Outside of the association of SS-A antibody with congenital heart block, little is known about adverse maternal and neonatal outcomes, in patients with Sjogren's disease (SjD). Our study involved collaboration with maternal\u2013fetal medicine (MFM).<\/jats:p><jats:p>A retrospective cohort study of pregnant patients: SjD patients were matched 1:3 with non-SjD controls. SjD patients were included by meeting the 2016 ACR\/EULAR Criteria or by a rheumatologist diagnosis. Exclusion criteria were concurrent autoimmune disease or related antibodies. A composite of grouped outcomes was utilized and verified by MFM specialists. The primary outcome was adverse pregnancy outcome (APO) between the two groups. Statistical analysis was performed using a two-sample t-test and Fisher's exact test.<\/jats:p><jats:p>48 patients were included: 12 SjD patients and 36 controls. APO was significantly increased in SjD with one preterm birth, one fetal growth restriction, and one limb anomaly; non-SjD had one cardiac anomaly. There were no cases of CHB. SjD patients were more likely to be delivered by cesarean delivery.<\/jats:p><jats:p>There was an increased risk of APO in SjD patients compared with controls. No significant difference in neonatal outcomes was found. We speculate that placental pathology may play a role in pathophysiology and future studies should be performed.<\/jats:p>","DOI":"10.1055\/a-2562-1643","type":"journal-article","created":{"date-parts":[[2025,3,19]],"date-time":"2025-03-19T23:53:11Z","timestamp":1742428391000},"page":"e47-e52","source":"Crossref","is-referenced-by-count":1,"title":["Adverse Pregnancy Outcomes in Sjogren's Disease Compared to Controls: An Interdisciplinary Approach with Maternal\u2013Fetal Medicine"],"prefix":"10.1055","volume":"15","author":[{"given":"Lauren","family":"Tesoriero","sequence":"additional","affiliation":[{"name":"Division of Rheumatology, Department of Internal Medicine, NYU Langone Hospital, Long Island, Mineola, New York"},{"name":"NYU Long Island School of Medicine, Mineola, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer","family":"Kidd","sequence":"additional","affiliation":[{"name":"Northwell Health New Hyde Park, New York"},{"name":"Donald and Barbara Zucker School of Medicine at Hofstra\/Northwell Uniondale, Uniondale, New York"},{"name":"Department of Obstetrics and Gynecology, Long Island Jewish Medical Center, New Hyde Park, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julie","family":"Piccione","sequence":"additional","affiliation":[{"name":"Division of Rheumatology, Department of Internal Medicine, NYU Langone Hospital, Long Island, Mineola, New York"},{"name":"NYU Long Island School of Medicine, Mineola, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Izmirly","sequence":"additional","affiliation":[{"name":"Division of Rheumatology, NYU Langone Health, New York, New York"},{"name":"NYU Grossman School of Medicine New York, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meredith","family":"Akerman","sequence":"additional","affiliation":[{"name":"NYU Long Island School of Medicine, Mineola, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven","family":"Carsons","sequence":"additional","affiliation":[{"name":"Division of Rheumatology, Department of Internal Medicine, NYU Langone Hospital, Long Island, Mineola, New York"},{"name":"NYU Long Island School of Medicine, Mineola, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4648-0583","authenticated-orcid":false,"given":"Patricia","family":"Rekawek","sequence":"additional","affiliation":[{"name":"NYU Long Island School of Medicine, Mineola, New York"},{"name":"Department of Maternal Fetal Medicine, NYU Langone Hospital, Long Island, Mineola, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julie","family":"Nusbaum","sequence":"additional","affiliation":[{"name":"Division of Rheumatology, Department of Internal Medicine, NYU Langone Hospital, Long Island, Mineola, New York"},{"name":"NYU Long Island School of Medicine, Mineola, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2025,4,8]]},"reference":[{"issue":"07","key":"ref1","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1002\/acr.23707","article-title":"The incidence and prevalence of adult primary Sj\u00f6gren's Syndrome in New York County","volume":"71","author":"P M Izmirly","year":"2019","journal-title":"Arthritis Care Res (Hoboken)"},{"issue":"9482","key":"ref2","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1016\/S0140-6736(05)66990-5","article-title":"Sj\u00f6gren's syndrome","volume":"366","author":"R I Fox","year":"2005","journal-title":"Lancet"},{"issue":"03","key":"ref3","doi-asserted-by":"crossref","first-page":"191","DOI":"10.7150\/ijms.17718","article-title":"Reviewing primary Sj\u00f6gren's syndrome: beyond the dryness - 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