{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T07:56:20Z","timestamp":1790841380710,"version":"4.1.0"},"reference-count":32,"publisher":"Georg Thieme Verlag KG","issue":"16","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am J Perinatol"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>This study aimed to explore the association of cytomegalovirus (CMV) infection in preterm infants of \u226432 weeks' gestation and neonatal morbidities.<\/jats:p>\n                  <jats:p>This was a matched cohort study of preterm infants born between 22 and 32 weeks gestation age and &lt;1,500\u2009g in birth weight who were admitted to participating tertiary NICUs within the Canadian Neonatal Network between April 2009 and December 2018. Infants were randomly matched in a 1:4 ratio (73 CMV-positive to 292 CMV-nonpositive infants) based on gestational age (in weeks), sex, birth weight (\u00b1\u200950\u2009g), and number of days of oxygen exposure within the first 28 days after birth (\u00b1\u20092 days). Neonatal morbidities were compared between the two groups using conditional logistic regression after adjustment of unmatched confounders.<\/jats:p>\n                  <jats:p>The CMV-positive infants were of lower median birth weight compared to CMV-nonpositive infants (722 vs. 743\u2009g; p\u2009&lt;\u20090.05). The duration of noninvasive respiratory support (59 vs. 43 days; p\u2009&lt;\u20090.05), invasive respiratory support (35 vs. 24 days; p\u2009&lt;\u20090.05), oxygen therapy (115 vs. 67 days; p\u2009&lt;\u20090.05), and odds of bronchopulmonary dysplasia (BPD; 90% vs. 71%; adjusted odds ratio: 3.52 [1.54, 8.07]) were higher for CMV-positive infants compared to CMV-nonpositive infants. Other morbidities were not statistically significantly different.<\/jats:p>\n                  <jats:p>CMV infection in very preterm infants was associated with increased duration of oxygen and respiratory support and increased odds of BPD.<\/jats:p>","DOI":"10.1055\/a-2565-1063","type":"journal-article","created":{"date-parts":[[2025,4,30]],"date-time":"2025-04-30T19:51:21Z","timestamp":1746042681000},"page":"2111-2117","source":"Crossref","is-referenced-by-count":4,"title":["Association of Cytomegalovirus Infection in Preterm Infants and Neonatal Outcomes: A Matched Cohort Study"],"prefix":"10.1055","volume":"42","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-9631-749X","authenticated-orcid":false,"given":"Emily","family":"Lo","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Neonatal Perinatal Fellowship Program, University of Toronto, Toronto, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prakesh S.","family":"Shah","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Neonatal Perinatal Fellowship Program, University of Toronto, Toronto, Ontario, Canada"},{"name":"Maternal-Infant Care Research Centre, Mount Sinai Hospital, Toronto, Ontario, Canada"},{"name":"Department of Pediatrics, Mount Sinai Hospital, Toronto, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean","family":"Chow","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miroslav","family":"Stavel","sequence":"additional","affiliation":[{"name":"Royal Columbian Hospital, New Westminster, British Columbia, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5696-8606","authenticated-orcid":false,"given":"Andrei","family":"Harabor","sequence":"additional","affiliation":[{"name":"Division of Neonatology, Regina General Hospital, Saskatchewan Health Authority, Pediatrics, Regina, Saskatchewan, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruben","family":"Alvaro","sequence":"additional","affiliation":[{"name":"Department of Pediatrics and Child Health, Section of Neonatology, Rady Faculty of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sajit","family":"Augustine","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Windsor Regional Hospital, University of Windsor, Windsor, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rudaina","family":"Banihani","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seungwoo","family":"Lee","sequence":"additional","affiliation":[{"name":"Maternal-Infant Care Research Centre, Mount Sinai Hospital, Toronto, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3399-0130","authenticated-orcid":false,"given":"Asaph","family":"Rolnitsky","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"on behalf of the Canadian Neonatal Network 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