{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T00:42:02Z","timestamp":1759884122207,"version":"build-2065373602"},"reference-count":21,"publisher":"Georg Thieme Verlag KG","issue":"07","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Thorac Cardiovasc Surg"],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Lung volume reduction surgery (LVRS) is an important treatment option for patients with advanced emphysema and is typically performed in a non-anatomical fashion. This study reports the outcome of anatomical LVRS by means of uniportal video-assisted thoracoscopic surgery (VATS).<\/jats:p><jats:p>We retrospectively evaluated patients who underwent anatomical LVRS between June 2017 and September 2023 at our institution. Patient characteristics, including demographic data, lung function, as well as morbidity and mortality, were extracted from hospital records.<\/jats:p><jats:p>A total of 44 patients (17 males, 38.6%) underwent anatomical LVRS at our institution during the observation period. The preoperative forced expiratory volume per second (FEV1) and FEV1% were 35.4\u2009\u00b1\u200920.0% and 45.7\u2009\u00b1\u200918.2%, respectively. Lobectomy was performed in 37 patients (84.1%), while segmentectomy was performed in 10 patients (22.7%, duplicated). Postoperative FEV1 and FEV1% significantly improved compared to preoperative values at the initial follow-up (11.8\u2009\u00b1\u20096.9 months after the operation): 38.3\u2009\u00b1\u200919.5%, p\u2009&lt;\u20090.002 and 49.4\u2009\u00b1\u200918.4%, p\u2009&lt;\u20090.01, respectively. Unfortunately, two patients (4.5%) died within 30 days postoperation. A further follow-up lung function test was performed in 25 patients (56.8%) at 33.1\u2009\u00b1\u200913.8 months after the operation, showing that FEV1 and FEV1% remained similar to the preoperative values (33.9\u2009\u00b1\u200920.7%, p\u2009=\u20090.10 and 45.3\u2009\u00b1\u200918.1%, p\u2009=\u20090.06, respectively).<\/jats:p><jats:p>Anatomical lung resection via uniportal VATS is an effective procedure for LVRS in patients with severe emphysema and is associated with acceptable morbidity and mortality.<\/jats:p>","DOI":"10.1055\/a-2572-6755","type":"journal-article","created":{"date-parts":[[2025,4,3]],"date-time":"2025-04-03T19:10:51Z","timestamp":1743707451000},"page":"571-576","source":"Crossref","is-referenced-by-count":0,"title":["Uniportal Video-Assisted Anatomical Lung Volume Reduction Surgery in Severe Emphysema"],"prefix":"10.1055","volume":"73","author":[{"given":"Hayan","family":"Merhej","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akylbek","family":"Saipbaev","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomoyuki","family":"Nakagiri","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alaa","family":"Selman","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Heiko","family":"Golpon","sequence":"additional","affiliation":[{"name":"Department of Pneumology and Respiratory Medicine, Hannover Medical School, Hannover, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tobias","family":"Goecke","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrick","family":"Zardo","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2025,4,30]]},"reference":[{"issue":"05","key":"ref1","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1016\/S2213-2600(21)00511-7","article-title":"Global, regional, and national prevalence of, and risk factors for, chronic obstructive pulmonary disease (COPD) in 2019: a systematic review and modelling analysis","volume":"10","author":"D Adeloye","year":"2022","journal-title":"Lancet Respir Med"},{"issue":"S 01","key":"ref2","doi-asserted-by":"crossref","first-page":"SI26","DOI":"10.1016\/S0140-6736(99)90227-1","article-title":"Lung-reduction surgery: 5 years on","volume":"353","author":"J D Cooper","year":"1999","journal-title":"Lancet"},{"issue":"02","key":"ref3","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1016\/j.athoracsur.2006.05.069","article-title":"Long-term follow-up of patients receiving lung-volume-reduction surgery versus medical therapy for severe emphysema by the National Emphysema Treatment Trial Research Group","volume":"82","author":"K S Naunheim","year":"2006","journal-title":"Ann Thorac Surg"},{"issue":"08","key":"ref4","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1164\/rccm.201103-0455CI","article-title":"The National Emphysema Treatment Trial (NETT) Part II: Lessons learned about lung volume reduction surgery","volume":"184","author":"G J Criner","year":"2011","journal-title":"Am J Respir Crit Care Med"},{"issue":"02","key":"ref5","doi-asserted-by":"crossref","first-page":"122","DOI":"10.7861\/clinmedicine.14-2-122","article-title":"Surgical approaches for lung volume reduction in emphysema","volume":"14","author":"S J Clark","year":"2014","journal-title":"Clin Med (Lond)"},{"issue":"09","key":"ref6","doi-asserted-by":"crossref","first-page":"818","DOI":"10.1002\/jhm.13416","article-title":"Clinical guideline highlights for the hospitalist: GOLD COPD update 2024","volume":"19","author":"T Cornelius","year":"2024","journal-title":"J Hosp Med"},{"issue":"02","key":"ref7","first-page":"131","article-title":"[Lung volume reduction surgery for emphysema and bullous pulmonary emphysema]","volume":"68","author":"F Le Pimpec-Barthes","year":"2012","journal-title":"Rev Pneumol Clin"},{"key":"ref8","first-page":"194","article-title":"A surgical approach to pulmonary emphysema","volume":"80","author":"O C Brantigan","year":"1959","journal-title":"Am Rev Respir Dis"},{"issue":"03","key":"ref9","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1016\/j.ejcts.2006.11.052","article-title":"Is there a role for therapeutic lobectomy for emphysema?","volume":"31","author":"P Vaughan","year":"2007","journal-title":"Eur J Cardiothorac Surg"},{"issue":"05","key":"ref10","doi-asserted-by":"crossref","first-page":"1319","DOI":"10.1016\/S0022-5223(96)70147-2","article-title":"Results of 150 consecutive bilateral lung volume reduction procedures in patients with severe emphysema","volume":"112","author":"J D Cooper","year":"1996","journal-title":"J Thorac Cardiovasc Surg"},{"issue":"03","key":"ref11","doi-asserted-by":"crossref","first-page":"822","DOI":"10.1016\/S0003-4975(96)01259-3","article-title":"Functional improvement after volume reduction: sternotomy versus videoendoscopic approach","volume":"63","author":"W Wisser","year":"1997","journal-title":"Ann Thorac Surg"},{"issue":"06","key":"ref12","doi-asserted-by":"crossref","first-page":"1858","DOI":"10.1016\/j.athoracsur.2020.06.148","article-title":"Consolidating lung volume reduction surgery after endoscopic lung volume reduction failure","volume":"111","author":"M E Eichhorn","year":"2021","journal-title":"Ann Thorac Surg"},{"issue":"04","key":"ref13","first-page":"336","article-title":"Unilateral lobe resection by video-assisted thoracoscopy leads to the most optimal functional improvement in severe emphysema","volume":"64","author":"F Beckers","year":"2016","journal-title":"Thorac Cardiovasc Surg"},{"issue":"02","key":"ref14","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1183\/09031936.00015312","article-title":"Radiological and clinical outcomes of using Chartis\u2122 to plan endobronchial valve treatment","volume":"41","author":"F J Herth","year":"2013","journal-title":"Eur Respir J"},{"key":"ref15","first-page":"S77","article-title":"Standards for the diagnosis and care of patients with chronic obstructive pulmonary disease","volume":"152","author":"American Thoracic Society","year":"1995","journal-title":"Am J Respir Crit Care Med"},{"volume-title":"Chronic Obstructive Pulmonary Disease","year":"2025","author":"A K Agarwal","key":"ref16"},{"issue":"19","key":"ref17","doi-asserted-by":"crossref","first-page":"1497","DOI":"10.1001\/jama.1994.03520190043033","article-title":"Effects of smoking intervention and the use of an inhaled anticholinergic bronchodilator on the rate of decline of FEV1. The Lung Health Study","volume":"272","author":"N R Anthonisen","year":"1994","journal-title":"JAMA"},{"issue":"04","key":"ref18","doi-asserted-by":"crossref","first-page":"1283","DOI":"10.1164\/ajrccm.155.4.9105068","article-title":"Quality of life changes in COPD patients treated with salmeterol","volume":"155","author":"P W Jones","year":"1997","journal-title":"Am J Respir Crit Care Med"},{"issue":"02","key":"ref19","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1164\/ajrccm.155.2.9032188","article-title":"Theoretical basis for improvement following reduction pneumoplasty in emphysema","volume":"155","author":"F G Hoppin Jr","year":"1997","journal-title":"Am J Respir Crit Care Med"},{"key":"ref20","first-page":"e66380","article-title":"Phase-Resolved Functional Lung MRI for Pulmonary Ventilation and Perfusion (V\/Q) Assessment","volume":"210","author":"A. Voskrebenzev","year":"2024","journal-title":"J Vis Exp"},{"issue":"04","key":"ref21","doi-asserted-by":"crossref","first-page":"1122","DOI":"10.1002\/jmri.26342","article-title":"Comparison of quantitative regional perfusion-weighted phase resolved functional lung (PREFUL) MRI with dynamic gadolinium-enhanced regional pulmonary perfusion MRI in COPD patients","volume":"49","author":"T F Kaireit","year":"2019","journal-title":"J Magn Reson Imaging"}],"container-title":["The Thoracic and Cardiovascular Surgeon"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-2572-6755.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,7]],"date-time":"2025-10-07T22:45:14Z","timestamp":1759877114000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-2572-6755"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,3]]},"references-count":21,"journal-issue":{"issue":"07","published-online":{"date-parts":[[2025,10,7]]},"published-print":{"date-parts":[[2025,10]]}},"URL":"https:\/\/doi.org\/10.1055\/a-2572-6755","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["0171-6425","1439-1902"],"issn-type":[{"type":"print","value":"0171-6425"},{"type":"electronic","value":"1439-1902"}],"subject":[],"published-other":{"date-parts":[[2025,4,3]]},"published":{"date-parts":[[2025,4,3]]}}}