{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T23:19:10Z","timestamp":1773271150478,"version":"3.50.1"},"reference-count":11,"publisher":"Georg Thieme Verlag KG","issue":"05","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Aktuelle Urol"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>\n    Die digitalen Gesundheitsanwendungen sind neben Arzneimitteln, Heilmitteln und Hilfsmitteln ein neuer Leistungsbereich nach \u00a733a SGB V. Mittlerweile sind 69 DiGA im Verzeichnis des BfArM gelistet; 40 davon dauerhaft. Die Voraussetzung f\u00fcr eine dauerhafte Listung ist eine randomisiert kontrollierte Studie (RCT) mit entsprechendem Wirknachweis. F\u00fcr die Beschwerden am unteren Harntrakt beim Mann (male LUTS) ist Kranus Lutera die erste zugelassene DiGA. Den Wirknachweis erbrachte die BEST-Studie. Insgesamt wurden in dieser Studie 237 Patienten randomisiert. Im Vergleich zur Kontrollgruppe zeigte die Interventionsgruppe eine signifikante Verbesserung des prim\u00e4ren Endpunkts IPSS (\u20137,0; 95%-KI: \u20138,1; \u20135,9; p&lt;0,0001) und der sekund\u00e4ren Endpunkte OAB-q-SF Teil 1 (Symptombelastung: \u201318,6; 95%-KI: \u201322,2; \u201315,0; p&lt;0,0001) und Teil 2 (gesundheitsbezogene Lebensqualit\u00e4t: +17,2; 95%-KI: 20,16; 14,8; p&lt;0,0001). Beide Untergruppen (BPH, OAB) profitierten \u00e4hnlich.\n    <\/jats:p>","DOI":"10.1055\/a-2573-7302","type":"journal-article","created":{"date-parts":[[2025,5,5]],"date-time":"2025-05-05T18:53:41Z","timestamp":1746471221000},"page":"445-450","source":"Crossref","is-referenced-by-count":2,"title":["Digitale Gesundheitsanwendung beim benignen Prostatasyndrom"],"prefix":"10.1055","volume":"56","author":[{"given":"Sandra Helen","family":"Sch\u00f6nburg","sequence":"additional","affiliation":[{"name":"Neuro-Urologie, BG Klinikum Bergmannstrost Halle, Halle (Saale), Germany"},{"name":"Universit\u00e4tsklinik und Poliklinik f\u00fcr Urologie und Nierentransplantation, Martin Luther University Halle Wittenberg, Halle, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2025,5,5]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"433","DOI":"10.1002\/nau.23897","article-title":"The International Continence Society (ICS) report on the terminology for adult male lower urinary tract and pelvic floor symptoms and dysfunction","volume":"38","author":"C D'Ancona","year":"2019","journal-title":"Neurourol Urodyn"},{"issue":"S 2","key":"ref2","doi-asserted-by":"publisher","first-page":"269","DOI":"10.1002\/pros.2990150508","article-title":"Urodynamics in benign prostatic hyperplasia: A survey","volume":"15","author":"T Hald","year":"1989","journal-title":"Prostate"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1067\/mob.2002.125704","article-title":"The Standardisation of Terminology of Lower Urinary Tract Function: Report from the Standardisation Subcommittee of the International Continence Society","volume":"21","author":"P Abrams","year":"2002","journal-title":"Neurourol Urodyn"},{"key":"ref4","isbn-type":"print","volume-title":"EAU Guideline on Non-Neurogenic Male Lower Urinary Tract Symptoms (LUTS). 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