{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,17]],"date-time":"2025-11-17T23:40:57Z","timestamp":1763422857698,"version":"3.45.0"},"reference-count":37,"publisher":"Georg Thieme Verlag KG","issue":"16","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am J Perinatol"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>This study aimed to investigate the correlation between body temperature change from postbirth resuscitation (Tr) to admission (Ta), the impact of the transition of Tr to Ta, and the rate of Ta normalization on prematurity-related complications.<\/jats:p>\n                  <jats:p>A single-center retrospective observational study was conducted on inborn infants\u2009&lt;\u200933 weeks gestational age, born between January 1, 2017, and May 31, 2021. Linear regression and multivariate logistic regression were used to evaluate the Tr-Ta relationship and to assess other associations. Normal body temperature was 36.5 to 37.5\u00b0C.<\/jats:p>\n                  <jats:p>From 568 eligible infants, 517 (91%) had both Tr and Ta records. Of these, 336\/517 (65.0%) had normal Ta. And 80\/336 infants (23.8%) with normal Ta had preceding abnormal Tr. Tr and Ta had a positive linear correlation (R\n                  2\u2009=\u20090.23, p\u2009&lt;\u20090.01). After adjusting for birth-to-NICU-admission time and perinatal factors, Tr hypothermia was associated with bronchopulmonary dysplasia (BPD; adjusted odds ratio [aOR]: 2.14, 95% confidence interval [CI]: 1.26\u20133.65, p\u2009&lt;\u20090.01) and Ta hypothermia was associated with death before discharge (aOR: 2.98, 95% CI: 1.18\u20137.53, p\u2009=\u20090.02). Infants experiencing hypothermia during Tr to Ta transition were at a higher risk for periventricular leukomalacia (PVL), specifically, transition from Tr hypothermia to Ta normothermia\/hyperthermia (aOR: 5.35, CI: 1.27\u201322.53, p\u2009=\u20090.02) and Tr hypothermia to Ta hypothermia (aOR: 4.72, CI: 1.13\u201319.79, p\u2009=\u20090.03). Transitioning from Tr hypothermia to Ta hypothermia was associated with a higher incidence of BPD (aOR: 1.84, 95% CI: 0.91\u20133.73, p\u2009=\u20090.09) and death (aOR: 2.96, 95% CI: 0.89\u20139.91, p\u2009=\u20090.08), though not statistically significant. Ta normalization at a rate of \u22650.5\u00b0C\/hour was associated with a reduced risk of developing BPD.<\/jats:p>\n                  <jats:p>Hypothermia during Tr-to-Ta transition was associated with an increased risk of PVL. Future research should explore the effects of abnormal temperature duration and magnitude on neonatal outcomes.<\/jats:p>","DOI":"10.1055\/a-2575-2994","type":"journal-article","created":{"date-parts":[[2025,4,30]],"date-time":"2025-04-30T19:51:21Z","timestamp":1746042681000},"page":"2191-2202","source":"Crossref","is-referenced-by-count":1,"title":["Impact of the Transition of Neonatal Body Temperature from Resuscitation to Admission on Prematurity Complications: A Retrospective Observational Study"],"prefix":"10.1055","volume":"42","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-5259-9081","authenticated-orcid":false,"given":"Nutchayavaree","family":"Limpivilas","sequence":"additional","affiliation":[{"name":"Division of Neonatology, Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pitiporn","family":"Siripattanapipong","sequence":"additional","affiliation":[{"name":"Division of Neonatology, Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Punnanee","family":"Wutthigate","sequence":"additional","affiliation":[{"name":"Division of Neonatology, Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Walaiporn","family":"Bowornkitiwong","sequence":"additional","affiliation":[{"name":"Division of Neonatology, Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7592-9899","authenticated-orcid":false,"given":"Ratchada","family":"Kitsommart","sequence":"additional","affiliation":[{"name":"Division of Neonatology, Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sopapan","family":"Ngerncham","sequence":"additional","affiliation":[{"name":"Division of Neonatology, Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Buranee","family":"Yangthara","sequence":"additional","affiliation":[{"name":"Division of Neonatology, Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2025,4,30]]},"reference":[{"issue":"02","key":"ref1","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1089\/ther.2021.0036","article-title":"Advances in the prevention and treatment of neonatal hypothermia in early birth","volume":"12","author":"J Liu","year":"2022","journal-title":"Ther Hypothermia Temp Manag"},{"volume-title":"Maternal Health and Safe Motherhood Programme and Meeting of Technical Working Group on Thermal Control of the Newborn. Thermal control of the newborn: a practical guide","year":"1993","author":"World Health Organization","key":"ref2"},{"issue":"04","key":"ref3","doi-asserted-by":"crossref","first-page":"e150277","DOI":"10.1001\/jamapediatrics.2015.0277","article-title":"Association between admission temperature and mortality and major morbidity in preterm infants born at fewer than 33 weeks' gestation","volume":"169","author":"Y Lyu","year":"2015","journal-title":"JAMA Pediatr"},{"key":"ref4","doi-asserted-by":"crossref","DOI":"10.1542\/9781610020251","volume-title":"Textbook of Neonatal Resuscitation","author":"The American Academy of Pediatrics; American Heart Association","year":"2016","edition":"7th ed."},{"issue":"01","key":"ref5","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1080\/14767058.2019.1597043","article-title":"Antecedents and outcomes of hypothermia at admission to the neonatal intensive care unit","volume":"34","author":"C Elbaum","year":"2021","journal-title":"J Matern Fetal Neonatal Med"},{"issue":"01","key":"ref6","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1186\/s12887-020-02221-7","article-title":"Association between admission hypothermia and outcomes in very low birth weight infants in China: a multicentre prospective study","volume":"20","author":"Y H Yu","year":"2020","journal-title":"BMC Pediatr"},{"issue":"10","key":"ref7","doi-asserted-by":"crossref","first-page":"386","DOI":"10.3345\/kjp.2019.00206","article-title":"Clinical impact of admission hypothermia in very low birth weight infants: results from Korean Neonatal Network","volume":"62","author":"N H Lee","year":"2019","journal-title":"Korean J Pediatr"},{"issue":"07","key":"ref8","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1007\/s00431-019-03386-9","article-title":"Admission hypothermia, neonatal morbidity, and mortality: evaluation of a multicenter cohort of very low birth weight preterm infants according to relative performance of the center","volume":"178","author":"J P de Siqueira Caldas","year":"2019","journal-title":"Eur J Pediatr"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.jpeds.2017.09.021","article-title":"Admission temperature and associated mortality and morbidity among moderately and extremely preterm infants","volume":"192","author":"A R Laptook","year":"2018","journal-title":"J Pediatr"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.jpeds.2016.04.016","article-title":"Admission hypothermia in very preterm infants and neonatal mortality and morbidity","volume":"175","author":"E Wilson","year":"2016","journal-title":"J Pediatr"},{"issue":"02","key":"ref11","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/j.jpeds.2013.09.049","article-title":"Hypothermia and early neonatal mortality in preterm infants","volume":"164","author":"M F de Almeida","year":"2014","journal-title":"J Pediatr"},{"issue":"11","key":"ref12","doi-asserted-by":"crossref","first-page":"e0164817","DOI":"10.1371\/journal.pone.0164817","article-title":"Hypothermia in preterm infants in the first hours after birth: occurrence, course and risk factors","volume":"11","author":"A Mank","year":"2016","journal-title":"PLoS One"},{"issue":"03","key":"ref13","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1016\/j.jpeds.2015.06.008","article-title":"Association of rewarming rate on neonatal outcomes in extremely low birth weight infants with hypothermia","volume":"167","author":"F Rech Morassutti","year":"2015","journal-title":"J Pediatr"},{"issue":"01","key":"ref14","doi-asserted-by":"crossref","first-page":"fmaa098","DOI":"10.1093\/tropej\/fmaa098","article-title":"Rapid vs. slow rewarming for management of moderate to severe hypothermia in low-birth-weight pre-term neonates-an open label randomized controlled trial","volume":"67","author":"P Jain","year":"2021","journal-title":"J Trop Pediatr"},{"issue":"03","key":"ref15","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1111\/j.1651-2227.1994.tb18090.x","article-title":"Rapid rewarming of severely hypothermic newborns during initial stabilization","volume":"83","author":"S R Daga","year":"1994","journal-title":"Acta Paediatr"},{"issue":"05","key":"ref16","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1007\/BF02758559","article-title":"Estimation of rewarming time in transported extramural hypothermic neonates","volume":"73","author":"N B Mathur","year":"2006","journal-title":"Indian J Pediatr"},{"issue":"5169","key":"ref17","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1136\/bmj.1.5169.303","article-title":"Cold injury in the newborn. A study of 70 cases","volume":"1","author":"B D Bower","year":"1960","journal-title":"BMJ"},{"issue":"03","key":"ref18","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1016\/S0022-3476(05)82056-6","article-title":"New Ballard Score, expanded to include extremely premature infants","volume":"119","author":"J L Ballard","year":"1991","journal-title":"J Pediatr"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1016\/j.jpeds.2018.01.043","article-title":"Bronchopulmonary dysplasia: executive summary of a workshop","volume":"197","author":"R D Higgins","year":"2018","journal-title":"J Pediatr"},{"issue":"04","key":"ref20","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1016\/S0022-3476(78)80282-0","article-title":"Incidence and evolution of subependymal and intraventricular hemorrhage: a study of infants with birth weights less than 1,500 gm","volume":"92","author":"L A Papile","year":"1978","journal-title":"J Pediatr"},{"issue":"S 01","key":"ref21","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1038\/s41390-020-1074-4","article-title":"Defining necrotizing enterocolitis: current difficulties and future opportunities","volume":"88","author":"R M Patel","year":"2020","journal-title":"Pediatr Res"},{"issue":"10","key":"ref22","doi-asserted-by":"crossref","first-page":"e51","DOI":"10.1016\/j.ophtha.2021.05.031","article-title":"International Classification of Retinopathy of Prematurity, Third Edition","volume":"128","author":"M F Chiang","year":"2021","journal-title":"Ophthalmology"},{"issue":"04","key":"ref23","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1001\/archpediatrics.2010.20","article-title":"Underestimation of developmental delay by the new Bayley-III Scale","volume":"164","author":"P J Anderson","year":"2010","journal-title":"Arch Pediatr Adolesc Med"},{"issue":"06","key":"ref24","doi-asserted-by":"crossref","first-page":"958","DOI":"10.1111\/apa.14230","article-title":"Cohort study from 11 European countries highlighted differences in the use and efficacy of hypothermia prevention strategies after very preterm birth","volume":"107","author":"E Wilson","year":"2018","journal-title":"Acta Paediatr"},{"issue":"01","key":"ref25","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1097\/01.ANC.0000346094.28110.11","article-title":"Use of the heated gel mattress and its impact on admission temperature of very low birth-weight infants","volume":"9","author":"P G Almeida","year":"2009","journal-title":"Adv Neonatal Care"},{"issue":"S 07","key":"ref26","first-page":"S32","article-title":"Effect of polyethylene bag to prevent heat loss in preterm infants at birth: a randomized controlled trial","volume":"94","author":"S Chantaroj","year":"2011","journal-title":"J Med Assoc Thai"},{"issue":"01","key":"ref27","doi-asserted-by":"crossref","first-page":"e135","DOI":"10.1542\/peds.2013-0279","article-title":"A randomized trial of exothermic mattresses for preterm newborns in polyethylene bags","volume":"132","author":"L K McCarthy","year":"2013","journal-title":"Pediatrics"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.jpeds.2017.09.006","article-title":"A randomized trial of conditioned or unconditioned gases for stabilizing preterm infants at birth","volume":"193","author":"L McGrory","year":"2018","journal-title":"J Pediatr"},{"issue":"06","key":"ref29","doi-asserted-by":"crossref","first-page":"1701","DOI":"10.1038\/s41390-022-02297-0","article-title":"Thermoregulation and golden hour practices in extremely preterm infants: an international survey","volume":"93","author":"P Jani","year":"2023","journal-title":"Pediatr Res"},{"issue":"09","key":"ref30","doi-asserted-by":"crossref","first-page":"e210775","DOI":"10.1001\/jamapediatrics.2021.0775","article-title":"Delivery room interventions for hypothermia in preterm neonates: a systematic review and network meta-analysis","volume":"175","author":"T Abiramalatha","year":"2021","journal-title":"JAMA Pediatr"},{"issue":"06","key":"ref31","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1093\/tropej\/fmt051","article-title":"Admission hypothermia among VLBW infants in Malaysian NICUs","volume":"59","author":"N Y Boo","year":"2013","journal-title":"J Trop Pediatr"},{"issue":"06","key":"ref32","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1038\/jp.2010.146","article-title":"Physiologic and pharmacologic considerations for hypothermia therapy in neonates","volume":"31","author":"S Zanelli","year":"2011","journal-title":"J Perinatol"},{"issue":"11","key":"ref33","doi-asserted-by":"crossref","first-page":"1795","DOI":"10.4103\/1673-5374.219034","article-title":"Pathophysiology of periventricular leukomalacia: what we learned from animal models","volume":"12","author":"N Zaghloul","year":"2017","journal-title":"Neural Regen Res"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.pediatrneurol.2021.08.003","article-title":"Risk factors for periventricular leukomalacia in preterm infants: a systematic review, meta-analysis, and GRADE-based assessment of certainty of evidence","volume":"124","author":"T Abiramalatha","year":"2021","journal-title":"Pediatr Neurol"},{"issue":"07","key":"ref35","doi-asserted-by":"crossref","first-page":"e0131976","DOI":"10.1371\/journal.pone.0131976","article-title":"Short- and long-term outcomes in very low birth weight infants with admission hypothermia","volume":"10","author":"H Y Chang","year":"2015","journal-title":"PLoS One"},{"issue":"01","key":"ref36","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1186\/s12884-020-03343-7","article-title":"Impact of temperature change from admission to day one on neonatal mortality in a low-resource setting","volume":"20","author":"F Cavallin","year":"2020","journal-title":"BMC Pregnancy Childbirth"},{"issue":"05","key":"ref37","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1055\/s-2000-10008","article-title":"Continuous measurement of core body temperature in preterm infants","volume":"17","author":"S Dollberg","year":"2000","journal-title":"Am J Perinatol"}],"container-title":["American Journal of Perinatology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-2575-2994.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,17]],"date-time":"2025-11-17T23:36:01Z","timestamp":1763422561000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-2575-2994"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,30]]},"references-count":37,"journal-issue":{"issue":"16","published-online":{"date-parts":[[2025,11,17]]},"published-print":{"date-parts":[[2025,12]]}},"URL":"https:\/\/doi.org\/10.1055\/a-2575-2994","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["0735-1631","1098-8785"],"issn-type":[{"type":"print","value":"0735-1631"},{"type":"electronic","value":"1098-8785"}],"subject":[],"published":{"date-parts":[[2025,4,30]]}}}