{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T12:42:39Z","timestamp":1781613759120,"version":"3.54.5"},"reference-count":25,"publisher":"Georg Thieme Verlag KG","issue":"05","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Aktuelle Urol"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:title>\n    Zusammenfassung\n    <\/jats:title><jats:p>\n       Untersuchung und Vergleich der klinischen Sicherheit und Effizienz der Holmium-Laserenukleation der Prostata (HoLEP) und der roboterassistierten, transvesikalen Enukleation der Prostata (RASP) zur Behandlung der benignen Prostatahyperplasie (BPH) mit gro\u00dfen Prostatavolumina in einem terti\u00e4ren Versorgungszentrum.\n      <\/jats:p><jats:p>\n       Erhoben wurden die perioperativen Daten von 39 Patienten, die zwischen 2015 und 2021 eine RASP in unserem Zentrum erhielten. Anhand des Prostatavolumens, des Patientenalters und des Body-Mass-Indexes (BMI) erfolgte ein Propensity Score Matching mit 721 mittels HoLEP an unserer Klinik behandelten Patienten. Pr\u00e4operative Parameter wie Prostatavolumen, Alter, BMI, PSA-Wert, IPSS-Score, IIEF-Score sowie intra- und postoperative Parameter wie Operationszeit, Resektionsgewicht, postoperative Katheterliegedauer, Krankenhausverweildauer, H\u00e4moglobinabfall, Transfusionsrate, postoperative Harnverhaltung, Clavien-Dindo-Klassifikation (CDC) und der Comprehensive Complication Index (CCI) wurden ausgewertet.\n      <\/jats:p><jats:p>\n      Es zeigte sich ein statistisch signifikanter Unterschied zugunsten der HoLEP hinsichtlich der Operationszeit (114,5 vs. 153,5 Minuten; p&lt;0,001), der Katheterliegedauer (2,6 vs. 7,4 Tage; p&lt;0,001) und der Krankenhausverweildauer (2,9 vs. 8,8 Tage; p&lt;0,001). Hinsichtlich des H\u00e4moglobinabfalls und der Transfusionsrate konnte kein statistisch signifikanter Unterschied nachgewiesen werden. Die Rate der Komplikationen war niedriger nach der HoLEP, jedoch nicht statistisch signifikant (p=0,051). In Bezug auf den Schweregrad der Komplikationen zeigte sich ein statistisch signifikanter Unterschied der CDC zuungunsten der RASP (p=0,027), der CCI wies jedoch keinen statistisch signifikanten Unterschied zwischen beiden Kohorten auf (p=0,098).\n      <\/jats:p><jats:p>\n      Sowohl HoLEP als auch RASP waren effektiv und sicher bei der Behandlung der BPH mit gro\u00dfem Prostatavolumina. Die HoLEP zeigte im Vergleich zu RASP Vorteile bei der Katheterisierungsdauer sowie der Krankenhausaufenthaltsdauer. Bez\u00fcglich der Rate an Komplikationen zeigten sich keine statistisch signifikanten Unterschiede.\n      <\/jats:p>","DOI":"10.1055\/a-2577-3748","type":"journal-article","created":{"date-parts":[[2025,5,21]],"date-time":"2025-05-21T19:22:08Z","timestamp":1747855328000},"page":"464-469","source":"Crossref","is-referenced-by-count":3,"title":["Stellenwert der Holmium-Laserenukleation der Prostata (HoLEP) im Vergleich zur roboterassistierten transvesikalen Enukleation der Prostata (RASP): eine Propensity-Score-Matched-Analyse"],"prefix":"10.1055","volume":"56","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1112-0705","authenticated-orcid":false,"given":"Friedrich Otto","family":"Hartung","sequence":"first","affiliation":[{"name":"Universit\u00e4tsklinikum Mannheim, Klinik f\u00fcr Urologie und Urochirurgie, Mannheim, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luisa","family":"Egen","sequence":"first","affiliation":[{"name":"Universit\u00e4tsklinikum Mannheim, Klinik f\u00fcr Urologie und Urochirurgie, Mannheim, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linus","family":"Breuer","sequence":"additional","affiliation":[{"name":"Universit\u00e4tsklinikum Mannheim, Klinik f\u00fcr Urologie und Urochirurgie, Mannheim, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Britta","family":"Gruene","sequence":"additional","affiliation":[{"name":"Universit\u00e4tsklinikum Mannheim, Klinik f\u00fcr Urologie und Urochirurgie, Mannheim, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher","family":"Netsch","sequence":"additional","affiliation":[{"name":"Abteilung f\u00fcr Urologie, Asklepios Klinik Barmbek, Hamburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benedikt","family":"Becker","sequence":"additional","affiliation":[{"name":"Abteilung f\u00fcr Urologie, Asklepios Klinik Barmbek, Hamburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maren","family":"Wenk","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Urologie und Urochirurgie, Universit\u00e4tsmedizin Mannheim, Mannheim, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonas","family":"Herrmann","sequence":"additional","affiliation":[{"name":"Vivantes Auguste-Viktoria-Klinikum, Urologisches Laserzentrum Berlin, Berlin, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2025,5,21]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1111\/j.1464-410X.2009.08427.x","article-title":"The prevalence of lower urinary tract symptoms (LUTS) in the USA, the UK and Sweden: results from the Epidemiology of LUTS (EpiLUTS) study","volume":"104","author":"KS Coyne","year":"2009","journal-title":"BJU 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