{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T18:31:49Z","timestamp":1780338709427,"version":"3.54.1"},"reference-count":12,"publisher":"Georg Thieme Verlag KG","issue":"05","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Zentralbl Chir"],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>Aortale Malignome sind seltene Erkrankungen von denen bisher nur knapp 200 F\u00e4lle in der Literatur beschrieben sind. Am h\u00e4ufigsten sind High-Grade-Sarkome in \u00fcber 80%, die \u00fcberwiegend intimal wachsen und an jeder Lokalisation der Aorta vorkommen k\u00f6nnen. Neben unspezifischen Symptomen wie Fieber, Hypertonie und allgemeiner Schw\u00e4che, manifestieren sich Aortensarkome in einem Drittel als Embolie oder im Falle von muralen Sarkomen als Aneurysma oder Ruptur. In der Diagnostik gilt die MRT als Goldstandard, da CT-Angiografie oder PET-CT nur unspezifische Zeichen aufweisen k\u00f6nnen. Da sich aortale Malignome h\u00e4ufig als andere Erkrankungen maskieren, sind Diagnostik und Therapie oft verz\u00f6gert. In der Therapie steht, wenn noch m\u00f6glich, die radikale Tumorentfernung im Vordergrund, auf die ggf. eine adjuvante medikament\u00f6se Therapie folgt. Das 1-, 3- und 5-Jahres-\u00dcberleben liegt nach Literaturlage bei 26%, 7,6% und 3,5%.<\/jats:p>","DOI":"10.1055\/a-2590-1736","type":"journal-article","created":{"date-parts":[[2025,5,19]],"date-time":"2025-05-19T19:49:18Z","timestamp":1747684158000},"page":"432-436","source":"Crossref","is-referenced-by-count":2,"title":["Maligne Tumoren der Aorta"],"prefix":"10.1055","volume":"150","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2126-3067","authenticated-orcid":false,"given":"Steffen","family":"Wolk","sequence":"additional","affiliation":[{"name":"Gef\u00e4\u00df- und endovaskul\u00e4re Chirurgie, Klinik und Poliklinik f\u00fcr Viszeral-, Thorax- und Gef\u00e4\u00dfchirurgie, Universit\u00e4tsklinikum Carl Gustav Carus Dresden, Technische Universit\u00e4t Dresden, Dresden, Deutschland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Reeps","sequence":"additional","affiliation":[{"name":"Gef\u00e4\u00df- und endovaskul\u00e4re Chirurgie, Klinik und Poliklinik f\u00fcr Viszeral-, Thorax- und Gef\u00e4\u00dfchirurgie, Universit\u00e4tsklinikum Carl Gustav Carus Dresden, Technische Universit\u00e4t Dresden, Dresden, Deutschland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2025,5,19]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"2922","DOI":"10.1002\/ijc.22239","article-title":"Incidence patterns of soft tissue sarcomas, regardless of primary site, in the surveillance, epidemiology and end results program, 1978\u20132001: An analysis of 26,758 cases","volume":"119","author":"JR Toro","year":"2006","journal-title":"Int J Cancer"},{"key":"ref2","first-page":"2303","article-title":"Angiosarcoma: a review of diagnosis and current treatment","volume":"9","author":"J Cao","year":"2019","journal-title":"Am J Cancer Res"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"1771","DOI":"10.1016\/j.jvs.2019.09.030","article-title":"Predictors of survival in malignant aortic tumors","volume":"71","author":"A Vacirca","year":"2020","journal-title":"J Vasc Surg"},{"key":"ref4","first-page":"243e6","article-title":"Primares Sarkom der Aorta thoracica mit Verbreitung des Neugebildes in der unteren Koerperhaelfte","volume":"8","author":"W Browdoski","year":"1873","journal-title":"Jahresb Leistung Fortschr Med"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"515","DOI":"10.1016\/j.avsg.2013.07.012","article-title":"Sarcomas of the aorta: a systematic review and pooled analysis of published reports","volume":"28","author":"CG Rusthoven","year":"2014","journal-title":"Ann Vasc Surg"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1002\/1097-0142(197201)29:1<73::aid-cncr2820290113>3.0.co;2-v","article-title":"Primary fibrosarcoma of aorta","volume":"29","author":"R Salm","year":"1972","journal-title":"Cancer"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"890","DOI":"10.1097\/00000478-198512000-00005","article-title":"Aortic intimal sarcoma with embolic metastases","volume":"9","author":"EP Wright","year":"1985","journal-title":"Am J Surg Pathol"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"548","DOI":"10.1016\/j.jvs.2004.06.035","article-title":"Intimal angiosarcoma of the aorta: report of a case and review of the literature","volume":"40","author":"A Thalheimer","year":"2004","journal-title":"J Vasc Surg"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1016\/j.anndiagpath.2016.01.002","article-title":"Angiosarcoma arising in association with vascular Dacron grafts and orthopedic joint prostheses: clinicopathologic, immunohistochemical, and molecular study","volume":"21","author":"A Agaimy","year":"2016","journal-title":"Ann Diagn Pathol"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.12659\/AJCR.931740","article-title":"Aortic Angiosarcoma in Association with Endovascular Aneurysm Repair: Case Report and Review of the Literature","volume":"22","author":"K Takamura","year":"2021","journal-title":"Am J Case Rep"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"377","DOI":"10.1053\/j.sult.2011.06.001","article-title":"Imaging sarcomas of the great vessels and heart","volume":"32","author":"EC Bendel","year":"2011","journal-title":"Semin Ultrasound CT MR"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1186\/1471-2342-13-25","article-title":"Imaging features of primary sarcomas of the great vessels in CT, MRI and PET\/CT: a single-center experience","volume":"13","author":"C von Falck","year":"2013","journal-title":"BMC Med Imaging"}],"container-title":["Zentralblatt f\u00fcr Chirurgie - 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