{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,21]],"date-time":"2025-11-21T23:40:02Z","timestamp":1763768402800,"version":"3.45.0"},"reference-count":154,"publisher":"Georg Thieme Verlag KG","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pneumologie"],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title>\n                  <jats:p>Das aktuelle Update der Leitlinie ber\u00fccksichtigt die seit 2016 publizierte wissenschaftliche Literatur sowie Erfahrungen aus der praktischen Anwendung. Sie richtet sich an \u00e4rztliche Gutachterinnen und Gutachter, die das Vorliegen einer Quarzstaublungenerkrankung als Berufskrankheit Nr.\u200a4101 der Anlage 1 zur BKV beurteilen und Aussagen zum urs\u00e4chlichen Zusammenhang mit der beruflichen Exposition, zu funktionellen Folgen und zur Minderung der Erwerbsf\u00e4higkeit (MdE) treffen. In der Leitlinie werden aktualisierte Diagnosekriterien, Differenzialdiagnosen und die f\u00fcr die Begutachtung relevanten Untersuchungen samt Bewertung dargestellt. Typische radiologische und pathologische Befunde, Verlaufsformen und Schweregrade der Silikose in Lungenparenchym, Hilus und Mediastinum werden auf Grundlage neuerer Publikationen und Empfehlungen beschrieben. Auch die Sonderform der Lymphknotensilikose und deren Anerkennung als Versicherungsfall der BK Nr.\u200a4101 (und 4112) bei nur geringen Lungenver\u00e4nderungen wird ber\u00fccksichtigt. Neue Kapitel behandeln die akute Silikoproteinose und die beschleunigte Silikose \u2013 Krankheitsbilder, die durch hohe oder sehr hohe Siliziumdioxidstaubbelastungen \u00fcber kurze Zeit entstehen. Eine umfangreiche Literaturanalyse weist zudem auf m\u00f6gliche Zusammenh\u00e4nge zwischen (auto-)immunbedingten bzw. entz\u00fcndlich-rheumatischen Erkrankungen und fr\u00fcherer Quarzstaubexposition hin \u2013 auch ohne manifeste Silikose. Die Autoren regen daher eine Bewertung des wissenschaftlichen Stands durch den \u00c4rztlichen Sachverst\u00e4ndigenbeirat Berufskrankheiten beim BMAS an. Das Update enth\u00e4lt zudem wesentliche Erweiterungen zur MdE-Einsch\u00e4tzung auf Basis der neuen Reichenhaller Empfehlung 2024, die als Vorschlag \u2013 auch zur m\u00f6glichen Integration in die n\u00e4chste \u201eBochumer Empfehlung\u201c \u2013 im Anhang dargestellt sind.<\/jats:p>","DOI":"10.1055\/a-2594-6457","type":"journal-article","created":{"date-parts":[[2025,8,12]],"date-time":"2025-08-12T22:50:13Z","timestamp":1755039013000},"page":"866-897","source":"Crossref","is-referenced-by-count":0,"title":["S2k-Leitlinie: Diagnostik und Begutachtung der Berufskrankheit Nr. 4101 Quarzstaublungenerkrankung (Silikose) der Berufskrankheitenverordnung (BKV)"],"prefix":"10.1055","volume":"79","author":[{"given":"Alexandra M.","family":"Preisser","sequence":"additional","affiliation":[{"name":"Zentralinstitut f\u00fcr Arbeitsmedizin und Maritime Medizin (ZfAM), Universit\u00e4tsklinikum Hamburg-Eppendorf (UKE), Hamburg, Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian","family":"Eisenhawer","sequence":"additional","affiliation":[{"name":"Institut f\u00fcr Pr\u00e4vention und Arbeitsmedizin der Deutschen Gesetzlichen Unfallversicherung, Institut der Ruhr-Universit\u00e4t Bochum (IPA), Bochum, Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lumini\u0163a I.","family":"Cervi\u0219","sequence":"additional","affiliation":[{"name":"Regierungspr\u00e4sidium Darmstadt, Fachzentrum f\u00fcr medizinischen Arbeitsschutz, Landesgewerbearzt, Wiesbaden, Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andreas","family":"Deimling","sequence":"additional","affiliation":[{"name":"Lungenpraxis Schleswig, Schleswig, Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melanie","family":"Duell","sequence":"additional","affiliation":[{"name":"Deutsche Gesetzliche Unfallversicherung e.\u200aV. 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