{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T20:45:55Z","timestamp":1784666755816,"version":"3.55.0"},"reference-count":9,"publisher":"Georg Thieme Verlag KG","issue":"CP","license":[{"start":{"date-parts":[[2025,6,17]],"date-time":"2025-06-17T00:00:00Z","timestamp":1750118400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Endosc Int Open"],"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Chronic radiation proctitis is a prevalent condition following pelvic radiation therapy, occasionally leading to significant blood loss. Although medical treatment and argon plasma coagulation (APC) are well-established options, endoscopic radiofrequency ablation (RFA) is an emerging treatment that has shown promising results in smaller studies. However, further research, particularly on long-term outcomes, is necessary. This study aimed to evaluate the treatment outcome of endoscopic RFA in patients with chronic radiation proctitis, with a particular focus on long-term outcome.<\/jats:p><jats:p>This retrospective study included all patients treated with RFA for radiation-induced chronic proctitis suffering from hematochezia at the Medical University of Innsbruck, Department of Visceral, Transplant and Thoracic Surgery, between 2018 and 2023.<\/jats:p><jats:p>Thirteen patients were included in the study, with RFA being the initial treatment in five cases. RFA sessions were performed once in nine patients, twice in three patients, and three times in one patient. After a median follow-up period of 58 months, 69.2% (n= 9) remained still symptom-free and 30.8% (n= 4) reported only mild rectal bleeding after hard stools.<\/jats:p><jats:p>These data indicate that RFA is a highly effective and safe treatment option for chronic radiation proctitis, providing excellent long-term results.<\/jats:p>","DOI":"10.1055\/a-2605-1079","type":"journal-article","created":{"date-parts":[[2025,6,17]],"date-time":"2025-06-17T23:18:47Z","timestamp":1750202327000},"source":"Crossref","is-referenced-by-count":3,"special_numbering":"S","title":["Radiofrequency ablation: Solution for a long-time therapeutic dilemma of chronic radiation proctitis?"],"prefix":"10.1055","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0986-5372","authenticated-orcid":false,"given":"Katharina","family":"Esswein","sequence":"additional","affiliation":[{"name":"Department of Visceral, Transplant and Thoracic Surgery, Medical University of Innsbruck, Innsbruck, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marijana","family":"Ninkovic","sequence":"additional","affiliation":[{"name":"Department of Visceral, Transplant and Thoracic Surgery, Medical University of Innsbruck, Innsbruck, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Veronika","family":"Kr\u00f6pfl","sequence":"additional","affiliation":[{"name":"Department of Visceral, Transplant and Thoracic Surgery, Medical University of Innsbruck, Innsbruck, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisabeth","family":"Gasser","sequence":"additional","affiliation":[{"name":"Department of Visceral, Transplant and Thoracic Surgery, Medical University of Innsbruck, Innsbruck, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christoph","family":"Profanter","sequence":"additional","affiliation":[{"name":"Department of Visceral, Transplant and Thoracic Surgery, Medical University of Innsbruck, Innsbruck, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2025,6,17]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"1135","DOI":"10.1097\/DCR.0000000000001209","article-title":"The American Society of Colon and Rectal Surgeons Clinical Practice Guidelines for the Treatment of Chronic Radiation Proctitis","volume":"61","author":"IM Paquette","year":"2018","journal-title":"Dis Colon Rectum"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"22","DOI":"10.5946\/ce.2020.288","article-title":"Radiation proctitis and management strategies","volume":"55","author":"DS Dahiya","year":"2022","journal-title":"Clin Endosc"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/j.gie.2019.04.234","article-title":"ASGE guideline on the role of endoscopy for bleeding from chronic radiation proctopathy","volume":"90","author":"JK Lee","year":"2019","journal-title":"Gastrointest Endosc"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"566","DOI":"10.3390\/life13020566","article-title":"A retrospective single-arm cohort study in a single center of radiofrequency ablation in treatment of chronic radiation proctitis","volume":"13","author":"CE Tang","year":"2023","journal-title":"Life (Basel)"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"428","DOI":"10.1016\/j.gie.2014.04.038","article-title":"Treatment of chronic radiation proctopathy with radiofrequency ablation (with video)","volume":"81","author":"T Rustagi","year":"2015","journal-title":"Gastrointest Endosc"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"1479","DOI":"10.1111\/jgh.14729","article-title":"Efficacy and safety of radiofrequency ablation for treatment of chronic radiation proctitis: A systematic review and meta-analysis","volume":"34","author":"TR McCarty","year":"2019","journal-title":"J Gastroenterol Hepatol"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"453","DOI":"10.2147\/CEG.S66534","article-title":"Radiofrequency ablation using BarRx for the endoscopic treatment of radiation proctopathy: a series of three cases","volume":"7","author":"A Patel","year":"2014","journal-title":"Clin Exp Gastroenterol"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"970","DOI":"10.1055\/s-0034-1377756","article-title":"Radiofrequency ablation for the treatment of radiation proctitis","volume":"46","author":"X Dray","year":"2014","journal-title":"Endoscopy"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1007\/s12664-017-0748-2","article-title":"Radiofrequency ablation for gastric antral vascular ectasia and radiation proctitis","volume":"36","author":"P Markos","year":"2017","journal-title":"Indian J Gastroenterol"}],"container-title":["Endoscopy International Open"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-2605-1079.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,17]],"date-time":"2025-06-17T23:18:55Z","timestamp":1750202335000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-2605-1079"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6,17]]},"references-count":9,"journal-issue":{"issue":"CP","published-online":{"date-parts":[[2025,1,7]]},"published-print":{"date-parts":[[2025]]}},"alternative-id":["a26051079"],"URL":"https:\/\/doi.org\/10.1055\/a-2605-1079","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["2364-3722","2196-9736"],"issn-type":[{"value":"2364-3722","type":"print"},{"value":"2196-9736","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,6,17]]}}}