{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T15:43:30Z","timestamp":1773157410099,"version":"3.50.1"},"reference-count":19,"publisher":"Georg Thieme Verlag KG","issue":"06","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dtsch Med Wochenschr"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>Was ist neu?<\/jats:title>\n                  <jats:p>Eisenmangel ist der h\u00e4ufigste N\u00e4hrstoffmangel weltweit. Auch Patientinnen und Patienten mit Herzinsuffizienz geh\u00f6ren zu einer besonders vulnerablen Gruppe. Hier spricht man bei einem Serum-Ferritin &lt; 100ng\/ml von Eisenmangel, alternativ bei einem Serum-Ferritin von 100\u2013299ng\/ml bei gleichzeitiger Transferrin-S\u00e4ttigung &lt; 20%.<\/jats:p>\n                  <jats:p>Die Ursachen der hohen Pr\u00e4valenz des Eisenmangels bei Herzinsuffizienz sind nicht abschlie\u00dfend gekl\u00e4rt. Faktoren wie chronische Entz\u00fcndungsprozesse oder die Einnahme bestimmter Medikamente (Acetylsalicyls\u00e4ure, Antikoagulanzien) kommen als Ausl\u00f6ser in Frage.<\/jats:p>\n                  <jats:p>Eine Vielzahl von Studien untersuchte die Therapie des Eisenmangels bei Herzinsuffizienz; die Ergebnisse waren nicht immer eindeutig. Die FAIR-HF-2-Studie konnte k\u00fcrzlich \u2013 im Gegensatz zu vorhergehenden Studien \u2013 den prim\u00e4ren kombinierten Endpunkt aus einer Reduktion von Hospitalisierung und Mortalit\u00e4t knapp nicht erreichen. Die korrekte Definition des Eisenmangels bei Herzinsuffizienz muss kritisch hinterfragt werden.<\/jats:p>","DOI":"10.1055\/a-2608-2406","type":"journal-article","created":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T23:30:25Z","timestamp":1773099025000},"page":"275-282","source":"Crossref","is-referenced-by-count":0,"title":["Herzinsuffizienz gezielt behandeln: Eisenmangel und intraven\u00f6se Eisensubstitution"],"prefix":"10.1055","volume":"151","author":[{"given":"Josefine","family":"Rudolph","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Kardiologie und Pneumologie, Universit\u00e4tsmedizin G\u00f6ttingen, G\u00f6ttingen"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryosuke","family":"Sato","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Kardiologie und Pneumologie, Universit\u00e4tsmedizin G\u00f6ttingen, G\u00f6ttingen"},{"name":"DZHK (Deutsches Zentrum f\u00fcr Herz- und Kreislaufforschung e. 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