{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,2]],"date-time":"2025-09-02T23:10:01Z","timestamp":1756854601654,"version":"3.44.0"},"reference-count":39,"publisher":"Georg Thieme Verlag KG","issue":"04","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Tierarztl Prax Ausg K Kleintiere Heimtiere"],"published-print":{"date-parts":[[2025,8]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>Die Aldosteronkonzentrationen und Schilddr\u00fcsenparameter bei Hunden mit\n                        Hypoadrenokortizismus (HA) zu untersuchen und m\u00f6gliche Hinweise auf einen\n                        Hypoaldosteronismus oder eine (autoimmune) Hypothyreose zu gewinnen.<\/jats:p><jats:p>Analysiert wurden asservierte Restblutproben von 29 Hunden mit nachgewiesenem\n                        HA. Die Aldosteronkonzentration wurde in der 0\u2009h- und 1\u2009h-Probe des\n                        Adrenocorticotropes-Hormon (ACTH)-Stimulationstests bestimmt. Die\n                        Konzentration des Gesamt-Thyroxins (Gesamt-T4), Thyreoidea-stimulierenden\n                        Hormons (TSH) und der Thyreoglobulin-Autoantik\u00f6rper (TgAA) wurden aus der\n                        0\u2009h- oder der 1h-Probe analysiert. Der Neutrophilen:Lymphozyten-Quotient,\n                        die Natrium(Na)-, Kalium(K)-Konzentration, der Na:K-Quotient und die\n                        Kreatininkonzentration zum Zeitpunkt des ACTH-Stimulationstests wurden\n                        retrospektiv betrachtet.<\/jats:p><jats:p>Bei 59% (17\/29) der Hunde konnte ein Hypoaldosteronismus mit\n                        Elektrolytverschiebungen nachgewiesen werden. Die Aldosteronkonzentration\n                        korrelierte mit dem Na:K-Quotienten. Zehn Prozent (3\/29) der Patienten hatte\n                        Elektrolytverschiebungen bei einer physiologischen Aldosteronkonzentration.\n                        Zu einer Hypothyreose passende Schilddr\u00fcsenhormonwerte, 2 davon inklusive\n                        erh\u00f6hter TgAA-Konzentrationen, lagen bei 10% (3\/29) der Hunde vor. Zehn\n                        Prozent (3\/29) der Tiere zeigten eine erh\u00f6hte TSH-Konzentration ohne\n                        Ver\u00e4nderungen der Gesamt-T4-Konzentration.<\/jats:p><jats:p>Die Aldosteronkonzentration ist bei vielen Hunden mit HA erniedrigt.\n                        Schilddr\u00fcsenhormonergebnisse sollten bei Patienten mit HA mit Vorsicht\n                        interpretiert werden.<\/jats:p>","DOI":"10.1055\/a-2620-8062","type":"journal-article","created":{"date-parts":[[2025,9,2]],"date-time":"2025-09-02T22:33:44Z","timestamp":1756852424000},"page":"202-208","source":"Crossref","is-referenced-by-count":0,"title":["Untersuchung zu endogenen Aldosteronkonzentrationen und\n                    Schilddr\u00fcsenparametern bei Hunden mit Hypoadrenokortizismus \u2013 eine\n                    Pilotstudie"],"prefix":"10.1055","volume":"53","author":[{"given":"Sina","family":"Strey","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Kleintiere, Stiftung Tier\u00e4rztliche Hochschule\n                    Hannover"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ina","family":"Leiter","sequence":"additional","affiliation":[{"name":"AG Veterin\u00e4r-Endokrinologie und Labordiagnostik, Stiftung Tier\u00e4rztliche\n                    Hochschule Hannover"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reinhard","family":"Mischke","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Kleintiere, Stiftung Tier\u00e4rztliche Hochschule\n                    Hannover"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marion","family":"Schmicke","sequence":"additional","affiliation":[{"name":"AG Veterin\u00e4r-Endokrinologie und Labordiagnostik, Stiftung Tier\u00e4rztliche\n                    Hochschule Hannover"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Johanna","family":"Rieder","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Kleintiere, Stiftung Tier\u00e4rztliche Hochschule\n                    Hannover"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2025,9,2]]},"reference":[{"key":"ref1","first-page":"1847","volume-title":"Hypoadrenocorticism. 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