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Schwerpunkte sind die aktuelle Definition der Rechtsherzinsuffizienz und ihre Abbildung durch RV-PA-Kopplungsparameter; pathomechanistische Fortschritte zu Entz\u00fcndung, Fibrose, metabolischer Dysfunktion und geschlechtsspezifischen Hormoneinfl\u00fcssen; die Rolle des rechten Vorhofs als Fr\u00fchmarker der RV-Belastung; Kriterien f\u00fcr adaptive versus maladaptive RV-Remodellierung mit invasiven und nicht-invasiven Messgr\u00f6\u00dfen; Auswirkungen neuer Therapien \u2013 insbesondere des Activin-Fallenproteins Sotatercept \u2013 auf H\u00e4modynamik und RV-Struktur; der translationale Wert gro\u00dfer Tiermodelle sowie praxisnahe Konsequenzen f\u00fcr multiparametrische Bildgebung. 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