{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,19]],"date-time":"2025-06-19T05:03:02Z","timestamp":1750309382183,"version":"3.41.0"},"reference-count":9,"publisher":"Georg Thieme Verlag KG","issue":"02","license":[{"start":{"date-parts":[[2025,6,6]],"date-time":"2025-06-06T00:00:00Z","timestamp":1749168000000},"content-version":"vor","delay-in-days":66,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["AJP Rep"],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A 26-year-old woman, gravida 1 para 0 at 14 weeks' 1-day gestation, presented with vaginal spotting and systemic symptoms, including palpitations, shortness of breath, heat intolerance, nausea, and vomiting for 2 weeks. Workup revealed maternal tachycardia, severe-range blood pressure, elevated beta human chorionic gonadotropin of 2,442,400 mIU\/mL, suppressed thyroid stimulating hormone, and elevated T4, consistent with thyroid storm with possible preeclampsia with severe features.1 A transvaginal ultrasound suggested a partial molar pregnancy; this was later confirmed by surgical pathology. This case highlights the rare yet serious complications of hydatidiform mole, in particular, a partial molar pregnancy, including thyroid storm and superimposed preeclampsia, emphasizing the importance of management at a tertiary care center with a multidisciplinary team to optimize maternal outcomes.2\n               3\n            <\/jats:p>","DOI":"10.1055\/a-2626-9145","type":"journal-article","created":{"date-parts":[[2025,6,6]],"date-time":"2025-06-06T23:16:16Z","timestamp":1749251776000},"page":"e94-e97","source":"Crossref","is-referenced-by-count":0,"title":["Thyroid Storm Triggered by Partial Hydatidiform Mole: A Rare and Life-Threatening Complication"],"prefix":"10.1055","volume":"15","author":[{"given":"Hailey","family":"Cox","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, University of Toledo and Toledo ProMedica Hospital, Toledo, Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maggie","family":"Wong","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, University of Toledo and Toledo ProMedica Hospital, Toledo, Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jena","family":"Preszler","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, University of Toledo and Toledo ProMedica Hospital, Toledo, Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nikolina","family":"Docheva","sequence":"additional","affiliation":[{"name":"Department of Maternal-Fetal Medicine, Toledo ProMedica Hospital, Toledo, Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nauman","family":"Khurshid","sequence":"additional","affiliation":[{"name":"Department of Maternal-Fetal Medicine, Toledo ProMedica Hospital, Toledo, Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2025,6,18]]},"reference":[{"issue":"07","key":"ref1","doi-asserted-by":"crossref","first-page":"e242131","DOI":"10.1136\/bcr-2021-242131","article-title":"Thyrotoxicosis: a rare presentation of molar pregnancy","volume":"14","author":"E De Guzman","year":"2021","journal-title":"BMJ Case Rep"},{"issue":"11","key":"ref2","doi-asserted-by":"crossref","first-page":"739","DOI":"10.4103\/0019-5049.170035","article-title":"Peri-operative concerns in a patient with thyroid storm secondary to molar pregnancy","volume":"59","author":"T Samra","year":"2015","journal-title":"Indian J Anaesth"},{"issue":"11","key":"ref3","first-page":"e19656","article-title":"Molar pregnancy complicated by impending thyroid storm","volume":"13","author":"S Sharma","year":"2021","journal-title":"Cureus"},{"issue":"05","key":"ref4","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1016\/S0034-7094(11)70071-X","article-title":"Thyrotoxic crisis associated with gestational trophoblastic disease","volume":"61","author":"C E de Almeida","year":"2011","journal-title":"Rev Bras Anestesiol"},{"issue":"12","key":"ref5","doi-asserted-by":"crossref","first-page":"6173","DOI":"10.1097\/MS9.0000000000001381","article-title":"Atypical presentation of hyperthyroidism complicated complete hydatidiform mole in a 24-year-old female: a case report","volume":"85","author":"M Mansour","year":"2023","journal-title":"Ann Med Surg (Lond)"},{"issue":"01","key":"ref6","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s13044-021-00092-3","article-title":"Hyperthyroidism in gestational trophoblastic disease - a literature review","volume":"14","author":"J V Pereira","year":"2021","journal-title":"Thyroid Res"},{"issue":"03","key":"ref7","doi-asserted-by":"crossref","first-page":"351","DOI":"10.3109\/01443615.2015.1065229","article-title":"Thyroid storm and early-onset proteinuric hypertension caused by a partial molar pregnancy","volume":"36","author":"J H Wie","year":"2016","journal-title":"J Obstet Gynaecol"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.cca.2020.09.028","article-title":"Hyperthyroidism in molar pregnancy: \u03b2-HCG levels do not always reflect severity","volume":"511","author":"B Chale-Matsau","year":"2020","journal-title":"Clin Chim Acta"},{"issue":"06","key":"ref9","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1016\/j.ajog.2010.06.073","article-title":"Gestational trophoblastic disease I: epidemiology, pathology, clinical presentation and diagnosis of gestational trophoblastic disease, and management of hydatidiform mole","volume":"203","author":"J R Lurain","year":"2010","journal-title":"Am J Obstet Gynecol"}],"container-title":["American Journal of Perinatology Reports"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-2626-9145.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,19]],"date-time":"2025-06-19T00:19:40Z","timestamp":1750292380000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-2626-9145"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4]]},"references-count":9,"journal-issue":{"issue":"02","published-online":{"date-parts":[[2025,4,8]]},"published-print":{"date-parts":[[2025,4]]}},"URL":"https:\/\/doi.org\/10.1055\/a-2626-9145","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["2157-6998","2157-7005"],"issn-type":[{"type":"print","value":"2157-6998"},{"type":"electronic","value":"2157-7005"}],"subject":[],"published-other":{"date-parts":[[2025,6,6]]},"published":{"date-parts":[[2025,4]]}}}