{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T16:51:59Z","timestamp":1791910319218,"version":"4.3.4"},"reference-count":18,"publisher":"Georg Thieme Verlag KG","issue":"CP","license":[{"start":{"date-parts":[[2025,6,16]],"date-time":"2025-06-16T00:00:00Z","timestamp":1750032000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Thrombosis Canada"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["TH Open"],"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Approximately 20% of patients with cancer will have cancer-associated venous thromboembolism (CAT), which is associated with significant morbidity and mortality. Despite its clinical importance, CAT awareness in cancer patients and caregivers remains low. We sought to assess the patients' knowledge of CAT through a national survey.<\/jats:p><jats:p>A survey assessing knowledge of different aspects of CAT was developed by a steering committee including four clinicians with expertise in CAT and a patient partner with lived experience. Survey dissemination among patients with cancer occurred through the Environics network, the Thrombosis Canada member network, the Thrombosis Canada social media platforms, and was advertised through Instagram and Facebook, and the Canadian Cancer Survivor Network newsletter.<\/jats:p><jats:p>Out of the 312 patients with cancer or survivors who responded to the survey, 179 (57.4%) were female, and 118 (37.8%) were over 65 years old. Overall, 119 patients (38.1%, 95% confidence interval [CI]: 37.7\u201349.8%) reported having no knowledge of CAT. Only 84 (26.9%, 95% CI: 22.1\u201332.2%) and 94 (30.1%, 95% CI: 25.1\u201335.6%) patients reported receiving education about their underlying risk of CAT or education about signs and symptoms of venous thromboembolism, respectively. A total of 66 (21%, 95% CI: 16.8\u201326.1%) patients reported being informed by a health care professional about considering thromboprophylaxis. Patients were interested in learning more about the risk of CAT, its associated risk factors, and the benefits and potential side effects of thromboprophylaxis.<\/jats:p><jats:p>Many patients with cancer lack awareness or knowledge of CAT. Our results highlight ongoing education and awareness of the CAT burden.<\/jats:p>","DOI":"10.1055\/a-2635-9296","type":"journal-article","created":{"date-parts":[[2025,6,16]],"date-time":"2025-06-16T23:06:11Z","timestamp":1750115171000},"source":"Crossref","is-referenced-by-count":1,"special_numbering":"S","title":["Patient's Awareness of Cancer-Associated Thrombosis: A Canadian Nationwide Survey"],"prefix":"10.1055","volume":"09","author":[{"given":"Ana C.","family":"Pizzarossa","sequence":"additional","affiliation":[{"name":"Hemostasis and Thrombosis Unit, Hospital de Cl\u00ednicas \u201cDr Manuel Quintela,\u201d Montevideo, Uruguay"},{"name":"Department of Medicine, University of Ottawa at the Ottawa Hospital and The Ottawa Hospital Research Institute, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Penaloza","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of Ottawa at the Ottawa Hospital and The Ottawa Hospital Research Institute, Ontario, Canada"},{"name":"Emergency Department, Cliniques Universitaires Saint-Luc, Universit\u00e9 Catholique de Louvain, Brussels, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristina","family":"Vrotniakaite-Bajerciene","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of Ottawa at the Ottawa Hospital and The Ottawa Hospital Research Institute, Ontario, Canada"},{"name":"Department of Hematology and Central Hematology Laboratory, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rufaro","family":"Chitsike","sequence":"additional","affiliation":[{"name":"Division of Medicine (Hematology), Memorial University of Newfoundland, St John's, Newfoundland and Labrador, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vicky","family":"Tagalakis","sequence":"additional","affiliation":[{"name":"Department of Medicine, Jewish General Hospital, Montr\u00e9al, Qu\u00e9bec, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan","family":"Calverley","sequence":"additional","affiliation":[{"name":"Thrombosis Canada, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc","family":"Carrier","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of Ottawa at the Ottawa Hospital and The Ottawa Hospital Research Institute, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2025,7,7]]},"reference":[{"issue":"04","key":"ref1","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1038\/s41569-022-00787-6","article-title":"Epidemiology and prevention of venous thromboembolism","volume":"20","author":"P L Lutsey","year":"2023","journal-title":"Nat Rev Cardiol"},{"issue":"01","key":"ref2","doi-asserted-by":"crossref","first-page":"e00229","DOI":"10.1016\/j.heliyon.2016.e00229","article-title":"Analysis of clinical factors affecting the rates of fatal pulmonary embolism and bleeding in cancer patients with venous thromboembolism","volume":"3","author":"J Trujillo-Santos","year":"2017","journal-title":"Heliyon"},{"issue":"04","key":"ref3","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1111\/j.1538-7836.2008.02908.x","article-title":"The incidence of venous thromboembolism among patients with primary lung cancer","volume":"6","author":"H K Chew","year":"2008","journal-title":"J Thromb Haemost"},{"issue":"05","key":"ref4","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1200\/JCO.19.01461","article-title":"Venous thromboembolism prophylaxis and treatment in patients with cancer: ASCO clinical practice guideline update","volume":"38","author":"N S Key","year":"2020","journal-title":"J Clin Oncol"},{"issue":"03","key":"ref5","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1111\/j.1538-7836.2007.02374.x","article-title":"Thromboembolism is a leading cause of death in cancer patients receiving outpatient chemotherapy","volume":"5","author":"A A Khorana","year":"2007","journal-title":"J Thromb Haemost"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"100557","DOI":"10.1016\/j.ctarc.2022.100557","article-title":"How well do European patients understand cancer-associated thrombosis? A patient survey","volume":"31","author":"A Falanga","year":"2022","journal-title":"Cancer Treat Res Commun"},{"issue":"12","key":"ref7","doi-asserted-by":"crossref","first-page":"2964","DOI":"10.1111\/jth.15902","article-title":"Awareness of venous thromboembolism among patients with cancer: Preliminary findings from a global initiative for World Thrombosis Day","volume":"20","author":"N Potere","year":"2022","journal-title":"J Thromb Haemost"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"337","DOI":"10.2147\/PPA.S79373","article-title":"Patients' Experiences of LIving with CANcer- associated thrombosis: the PELICAN study","volume":"9","author":"S Noble","year":"2015","journal-title":"Patient Prefer Adherence"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.thromres.2020.06.024","article-title":"Patients experience of living with cancer associated thrombosis in France (Le PELICAN)","volume":"194","author":"I Mah\u00e9","year":"2020","journal-title":"Thromb Res"},{"issue":"03","key":"ref10","doi-asserted-by":"crossref","first-page":"e0152084","DOI":"10.1371\/journal.pone.0152084","article-title":"Patient preferences for receiving education on venous thromboembolism prevention - A survey of stakeholder organizations","volume":"11","author":"V O Popoola","year":"2016","journal-title":"PLoS ONE"},{"key":"ref11","first-page":"2366","article-title":"The Dillman total design survey method","volume":"32","author":"S N Hoddinott","year":"1986","journal-title":"Can Fam Physician"},{"issue":"02","key":"ref12","first-page":"MR000008","article-title":"Methods to increase response rates to postal questionnaires","author":"P Edwards","year":"2007","journal-title":"Cochrane Database Syst Rev"},{"issue":"05","key":"ref13","doi-asserted-by":"crossref","first-page":"e12545","DOI":"10.1002\/rth2.12545","article-title":"A mixed-methods study to evaluate a patient-designed tool to reduce harm from cancer-associated thrombosis: The EMPOWER study","volume":"5","author":"E Baddeley","year":"2021","journal-title":"Res Pract Thromb Haemost"},{"issue":"08","key":"ref14","doi-asserted-by":"crossref","first-page":"1365","DOI":"10.1111\/jth.13031","article-title":"Global public awareness of venous thromboembolism","volume":"13","author":"A M Wendelboe","year":"2015","journal-title":"J Thromb Haemost"},{"issue":"09","key":"ref15","doi-asserted-by":"crossref","first-page":"e868","DOI":"10.1200\/JOP.19.00697","article-title":"Successful model for guideline implementation to prevent cancer-associated thrombosis: Venous thromboembolism prevention in the ambulatory cancer clinic","volume":"16","author":"C E Holmes","year":"2020","journal-title":"JCO Oncol Pract"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.tru.2024.100187","article-title":"Practical model for implementation of cancer-associated thrombosis prevention in the outpatient setting","volume":"16","author":"J Grama\u00e7a","year":"2024","journal-title":"Thromb Update"},{"key":"ref17","first-page":"215","article-title":"Patient education program at the forefront of cancer-associated thrombosis care","volume":"46","author":"M Sebuhyan","year":"2021","journal-title":"J Med Vasc"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1182\/blood-2020-137153","article-title":"Success of online CME at improving knowledge and confidence around guideline-directed management of cancer-associated thrombosis","author":"C Padbury","year":"2020","journal-title":"Blood"}],"container-title":["TH Open"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-2635-9296.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,7]],"date-time":"2025-07-07T23:52:49Z","timestamp":1751932369000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-2635-9296"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6,16]]},"references-count":18,"journal-issue":{"issue":"CP","published-online":{"date-parts":[[2025,1,27]]},"published-print":{"date-parts":[[2025]]}},"alternative-id":["a26359296"],"URL":"https:\/\/doi.org\/10.1055\/a-2635-9296","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["2512-9465"],"issn-type":[{"value":"2512-9465","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2025,6,16]]},"published":{"date-parts":[[2025,6,16]]}}}