{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,28]],"date-time":"2026-03-28T17:07:07Z","timestamp":1774717627948,"version":"3.50.1"},"reference-count":57,"publisher":"Georg Thieme Verlag KG","issue":"14","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J Sports Med"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>The study aimed to investigate the effects of exercise-induced muscle damage on\n                    muscle and cerebral oxygenation. Twelve healthy men performed eccentric exercise\n                    on a leg press machine at an intensity corresponding to their concentric\n                    one-repetition maximum. Muscle damage indices, muscle and cerebral oxygenation,\n                    and vastus lateralis architecture were evaluated at baseline and 48 hours\n                    postexercise. At 48 hours postexercise, delayed onset muscle soreness\n                    significantly increased (1.0\u00b10.3 to 4.2\u00b12.8; p&lt;0.01), while concentric\n                    one-repetition maximum, maximal isometric force, and rate of force development\n                    decreased (p&lt;0.01). The quadriceps\u2019 cross-sectional area and muscle\n                    thickness significantly increased (p&lt;0.05). During a 5-second maximal\n                    isometric contraction, the tissue oxygen saturation index (TSI) of the vastus\n                    lateralis (63\u00b13\u201361\u00b14%; p&gt;0.05) and the prefrontal cortex (68\u00b12\u201367\u00b11%;\n                        p&gt;0.05) did not change significantly. Deoxyhemoglobin showed a\n                    marginally significant decrease (1.16\u00b11.14\u20130.06\u00b11.10 \u00b5M; p=0.049). No\n                    significant changes were observed in muscle and cerebral oxygenation parameters\n                    during the 30-second maximal isometric contraction. The eccentric exercise\n                    protocol induced muscle damage and altered muscle architecture. However, these\n                    changes were not sufficient to affect muscle or cerebral TSI during either\n                    short- or long-duration maximal isometric contraction. Eccentric\n                    exercise-induced muscle damage was not found to induce changes in cerebral\n                    oxygenation.<\/jats:p>","DOI":"10.1055\/a-2644-4923","type":"journal-article","created":{"date-parts":[[2025,6,26]],"date-time":"2025-06-26T18:55:05Z","timestamp":1750964105000},"page":"1049-1060","source":"Crossref","is-referenced-by-count":2,"title":["The Effect of Exercise-Induced Muscle Damage on Muscle and Cerebral\n                    Oxygenation and Performance"],"prefix":"10.1055","volume":"46","author":[{"given":"Vassilis","family":"Bobotas","sequence":"additional","affiliation":[{"name":"School of Physical Education and Sport Science, National\n                    and Kapodistrian University of Athens, Athens, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Panagiotis N","family":"Chatzinikolaou","sequence":"additional","affiliation":[{"name":"Departmen of Physical Educaiton and Sport Science at\n                    Serres, Aristoteleio Panepistemio Thessalonikes, Thessaloniki,\n                    Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Spyridon","family":"Methenitis","sequence":"additional","affiliation":[{"name":"School of Physical Education and Sport Science, National\n                    and Kapodistrian University of Athens, Athens, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eleni","family":"Doika","sequence":"additional","affiliation":[{"name":"School of Physical Education and Sport Science, National\n                    and Kapodistrian University of Athens, Athens, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Polyxeni","family":"Spiliopoulou","sequence":"additional","affiliation":[{"name":"School of Physical Education and Sport Science, National\n                    and Kapodistrian University of Athens, Athens, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vassiliki J","family":"Malliou","sequence":"additional","affiliation":[{"name":"Department of Physical Education and Sport Science,\n                    National and Kapodistrian University of Athens, Athens, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Mpampoulis","sequence":"additional","affiliation":[{"name":"School of Physical Education and Sport Science, National\n                    and Kapodistrian University of Athens, Athens, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gerasimos","family":"Terzis","sequence":"additional","affiliation":[{"name":"Physical Education and Sports Science, National and\n                    Kapodistrian University of Athens, Athens, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nikolaos","family":"Geladas","sequence":"additional","affiliation":[{"name":"Physical Education and Sports Science, National and\n                    Kapodistrian University of Athens, 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Perentis","year":"2021","journal-title":"J Funct Morphol Kinesiol"},{"key":"ref36","doi-asserted-by":"publisher","first-page":"1360","DOI":"10.1152\/japplphysiol.00166.2018","article-title":"Understanding near infrared spectroscopy and its application to skeletal muscle\n                    research","volume":"126","author":"T J Barstow","year":"2019","journal-title":"J Appl Physiol (1985)"},{"key":"ref37","doi-asserted-by":"publisher","first-page":"337","DOI":"10.1111\/j.1475-097X.2011.01020.x","article-title":"Reproducibility and sensitivity of muscle reoxygenation and oxygen uptake\n                    recovery kinetics following running exercise in the field","volume":"31","author":"M Buchheit","year":"2011","journal-title":"Clin Physiol Funct Imaging"},{"key":"ref38","doi-asserted-by":"publisher","first-page":"2369","DOI":"10.1007\/s00421-011-2183-x","article-title":"Reliability of near infrared spectroscopy (NIRS) for measuring forearm\n                    oxygenation during 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