{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T23:18:19Z","timestamp":1783120699752,"version":"3.54.6"},"reference-count":37,"publisher":"Georg Thieme Verlag KG","issue":"04","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Neurol Surg B Skull Base"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Craniopharyngiomas are rare parasellar tumors, and papillary craniopharyngiomas (PCPs) represent 8 to 20% of cases.<\/jats:p>\n                  <jats:p>Interim analysis of retrospective data collected from the Registry of Adenomas of the Pituitary and Related Disorders (RAPID).<\/jats:p>\n                  <jats:p>Fourteen U.S.-based academic skull base centers between 2011 and 2023.<\/jats:p>\n                  <jats:p>Patients with PCPs.<\/jats:p>\n                  <jats:p>Demographic, imaging, surgical, and outcome variables.<\/jats:p>\n                  <jats:p>Ninety-nine patients with PCPs were included. The mean age was 51.8\u2009\u00b1\u200914.7, and 57.6% were male. Most tumors showed mixed cystic\/solid components (67.5%), were transinfundibular (50.0%), and were treated with an endoscopic endonasal approach (74.5%), with 51.1% demonstrating gross total resection (GTR). Pituitary stalk was preserved in 51.9%. Permanent arginine vasopressin deficiency was seen in 67.1% and was associated with pituitary stalk sacrifice (p\u2009=\u20090.003). Cerebrospinal fluid leak was the most common nonendocrine postsurgical, 30-day complication (9.1%), reason for return to the operating room (3.1%), and reason for 90-day readmission (8.1%). Most patients (63.9%) received no adjuvant therapy; GTR was associated with decreased radiotherapy use (p\u2009=\u20090.0001). BRAFV600E\n                   mutation was detected in 64\/69 tumors tested, although only one patient was treated with a BRAF inhibitor. A mean follow-up of 12.3\u2009\u00b1\u200914.6 months was seen for the group.<\/jats:p>\n                  <jats:p>RAPID consortium enabled the largest real-world clinical information dataset for PCPs. Early findings support that GTR and stalk preservation are important to outcomes. Iterative analysis and discussion of data led to the generation of a framework for future studies to fully leverage the capabilities of multicenter registries.<\/jats:p>","DOI":"10.1055\/a-2646-2339","type":"journal-article","created":{"date-parts":[[2025,7,18]],"date-time":"2025-07-18T23:24:22Z","timestamp":1752881062000},"page":"406-413","source":"Crossref","is-referenced-by-count":2,"title":["Early Findings from the Multicenter RAPID Consortium on Papillary Craniopharyngiomas"],"prefix":"10.1055","volume":"87","author":[{"given":"Michael P.","family":"Catalino","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University of Virginia, Charlottesville, Virginia, United States"},{"name":"Division of Endocrinology and Metabolism, University of Virginia, Charlottesville, Virginia, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Duy","family":"Pham","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University of Virginia, Charlottesville, Virginia, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert C.","family":"Rennert","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Clinical Neurosciences Center, University of Utah, Salt Lake City, Utah, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0070-0053","authenticated-orcid":false,"given":"William T.","family":"Couldwell","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Clinical Neurosciences Center, University of Utah, Salt Lake City, Utah, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James J","family":"Evans","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Thomas Jefferson University, Philadelphia, Pennsylvania, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Calen","family":"Callopy","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Thomas Jefferson University, Philadelphia, Pennsylvania, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Won","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University of California \u2013 Los Angeles, Los Angeles, California, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donato","family":"Pacione","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, New York University Langone Medical Center, New York, New York, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carter M.","family":"Suryadevara","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, New York University Langone Medical Center, New York, New York, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Albert","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Washington University School of Medicine in Saint Louis, St. Louis, Missouri, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julie","family":"Silverstein","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Washington University School of Medicine in Saint Louis, St. Louis, Missouri, United States"},{"name":"Division of Endocrinology, Metabolism, and Lipid Research, Washington University School of Medicine in Saint Louis, St. Louis, Missouri, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0689-8603","authenticated-orcid":false,"given":"Michael","family":"Chicoine","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University of Missouri, Columbia, Missouri, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul A.","family":"Gardner","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University of Pittsburgh Medical Center Health System, Pittsburgh, Pennsylvania, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Garni","family":"Barkhoudarian","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Pacific Neuroscience Institute, Los Angeles, California, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan C. Fernandez","family":"Miranda","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Stanford University, Palo Alto, California, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carolina","family":"Benjamin","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University of Miami Miller School of Medicine, Miami, Florida, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3217-8279","authenticated-orcid":false,"given":"Varun R.","family":"Kshettry","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Cleveland Clinic Foundation, Cleveland, Ohio, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriel","family":"Zada","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University of Southern California, Los Angeles, California, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8087-7870","authenticated-orcid":false,"given":"Jamie J. Van","family":"Gompel","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Mayo Clinic, Rochester, Minnesota, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandhya R.","family":"Palit","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Mayo Clinic, Rochester, Minnesota, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nathan","family":"Zwagerman","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Medical College of Wisconsin, Milwaukee, Wisconsin, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephanie","family":"Cheok","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Medical College of Wisconsin, Milwaukee, Wisconsin, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Prevedello","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, The Ohio State University, Columbus, Ohio, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyle C.","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, The Ohio State University, Columbus, Ohio, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam","family":"Mamelak","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, California, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"Pacult","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, Arizona, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Little","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, Arizona, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Karsy","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University of Michigan, Ann Arbor, Michigan, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2025,7,18]]},"reference":[{"issue":"04","key":"ref1","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1007\/s11102-021-01127-6","article-title":"Descriptive epidemiology of craniopharyngiomas in the United States","volume":"24","author":"A A Momin","year":"2021","journal-title":"Pituitary"},{"issue":"01","key":"ref2","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1007\/s10143-022-01942-w","article-title":"Long-term outcomes after a transcranial microsurgical approach to craniopharyngiomas: A 20-year clinical follow-up study","volume":"46","author":"X 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