{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T02:46:24Z","timestamp":1785552384699,"version":"3.56.0"},"reference-count":148,"publisher":"Georg Thieme Verlag KG","issue":"05","funder":[{"DOI":"10.13039\/100006380","name":"Rehabilitation Research and Development Service","doi-asserted-by":"crossref","award":["1IK2RX003661"],"award-info":[{"award-number":["1IK2RX003661"]}],"id":[{"id":"10.13039\/100006380","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Semin Respir Crit Care Med"],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>The number of lung cancer survivors\u2014anyone living with and beyond a lung cancer diagnosis\u2014is increasing along with advances in screening, early detection, and treatment. Following diagnosis and treatment, however, many lung cancer survivors experience high symptom burden and functional challenges that culminate in poor health-related quality of life (HRQL). We incorporated the cancer life course endorsed by the United States National Academy of Medicine (formerly Institute of Medicine) and reviewed interventions to improve HRQL, starting from the time of diagnosis, during or following curative intent treatment, noncurative intent treatment, and continued until changes in disease status and\/or goals of care. We reviewed clinical guidelines from the American College of Chest Physicians on HRQL following curative intent therapy, symptom management, and supportive care in lung cancer, as well as the role of exercise-based rehabilitation, complementary therapies, and integrative medicine. Moreover, we identified interventions evaluated in 19 randomized controlled trials (RCTs) or pilot RCTs in the past 10 years, involving 2,506 participants, to address HRQL challenges reported by \u226580% of lung cancer survivors as \u201cimportant\u201d or \u201cvery important\u201d: dyspnea, fatigue, sleep difficulties, fear\/distress, anxiety, depressive symptoms, physical or role function\/independence. This narrative review, which incorporates findings from physical exercise and rehabilitation, cognitive-behavioral and psychological therapies, mind-body therapies, mindfulness-based interventions, and other complementary therapies, has significant implications for enhancing the HRQL of the growing population of lung cancer survivors.<\/jats:p>","DOI":"10.1055\/a-2649-9311","type":"journal-article","created":{"date-parts":[[2025,7,7]],"date-time":"2025-07-07T19:52:13Z","timestamp":1751917933000},"page":"436-451","source":"Crossref","is-referenced-by-count":4,"title":["Survivorship Challenges and Supportive Care in Lung Cancer"],"prefix":"10.1055","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3003-9438","authenticated-orcid":false,"given":"Duc M.","family":"Ha","sequence":"additional","affiliation":[{"name":"Section of Pulmonary and Critical Care, Rocky Mountain Regional Veterans Affairs Medical Center, Aurora, Colorado"},{"name":"Division of Pulmonary Sciences and Critical Care Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3192-536X","authenticated-orcid":false,"given":"Regina A.","family":"Jacob","sequence":"additional","affiliation":[{"name":"Department of Medicine, Donald and Barbara Zucker School of Medicine at Hofstra\/Northwell, Manhasset, New York"},{"name":"Northwell Cancer Institute, New Hyde Park, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3377-7444","authenticated-orcid":false,"given":"Brett C.","family":"Bade","sequence":"additional","affiliation":[{"name":"Department of Medicine, Donald and Barbara Zucker School of Medicine at Hofstra\/Northwell, Manhasset, New York"},{"name":"Northwell Cancer Institute, New Hyde Park, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2025,7,30]]},"reference":[{"issue":"01","key":"ref3","first-page":"7","article-title":"Cancer statistics, 2022","volume":"72","author":"R L Siegel","year":"2022","journal-title":"CA Cancer J Clin"},{"issue":"01","key":"ref4","first-page":"7","article-title":"Cancer statistics, 2021","volume":"71","author":"R L Siegel","year":"2021","journal-title":"CA Cancer J Clin"},{"issue":"07","key":"ref5","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1056\/NEJMoa1916623","article-title":"The effect of advances in lung-cancer treatment on population mortality","volume":"383","author":"N Howlader","year":"2020","journal-title":"N Engl J Med"},{"issue":"05","key":"ref6","first-page":"409","article-title":"Cancer treatment and survivorship statistics, 2022","volume":"72","author":"K D Miller","year":"2022","journal-title":"CA Cancer J 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