{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T13:20:04Z","timestamp":1780492804086,"version":"3.54.1"},"reference-count":10,"publisher":"Georg Thieme Verlag KG","issue":"06","funder":[{"name":"National Multiple Sclerosis Society","award":["CF-2307-42107"],"award-info":[{"award-number":["CF-2307-42107"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neuropediatrics"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Early treatment improves long-term outcomes for persons living with multiple sclerosis (MS). Patients with pediatric-onset multiple sclerosis (POMS) experience delays in diagnosis and treatment with disease-modifying therapy (DMT). Here, we explore how a dedicated nurse care coordinator decreases time to treatment in POMS.<\/jats:p>\n                  <jats:p>We included a retrospective cohort of 60 POMS at a single center between 2018 and 2024. The primary outcome was time to DMT initiation. Secondary outcomes included relapse rates and Extended Disability Status Scale (EDSS) scores.<\/jats:p>\n                  <jats:p>In 60 participants, 39 were in the precoordinator group and 21 were in the postcoordinator group. Age, race, ethnicity, insurance, and the area deprivation index did not affect outcomes. However, the postcoordinator group had a shorter time from diagnosis to initiation of DMT (median: 49 days, interquartile range [IQR]: 40\u201357 days) compared to the precoordinator group (median: 126 days, IQR: 57\u2013254 days, p\u2009&lt;\u20090.001).<\/jats:p>\n                  <jats:p>Here, we found that a care coordinator decreased time to DMT initiation and should be implemented in clinical care.<\/jats:p>\n                  <jats:p>Having a dedicated nurse coordinator to help patients with MS with obtaining their treatments, including their DMTs, can result in a shorter time to starting a DMT.<\/jats:p>","DOI":"10.1055\/a-2650-6894","type":"journal-article","created":{"date-parts":[[2025,7,9]],"date-time":"2025-07-09T12:42:24Z","timestamp":1752064944000},"page":"388-391","source":"Crossref","is-referenced-by-count":1,"title":["Impact of a Nurse Care Coordinator on Time to Treatment in a Pediatric Multiple Sclerosis Clinic, a Retrospective Study"],"prefix":"10.1055","volume":"56","author":[{"given":"Madeleine H.","family":"McLaughlin","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Division of Neurology and Children's Healthcare of Atlanta, Division of Pediatric Neurology, Emory University School of Medicine, Atlanta, Georgia, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4830-7792","authenticated-orcid":false,"given":"Grace","family":"Gombolay","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Division of Neurology and Children's Healthcare of Atlanta, Division of Pediatric Neurology, Emory University School of Medicine, Atlanta, Georgia, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2025,7,24]]},"reference":[{"key":"ref1","first-page":"jnnp-2024-335175","article-title":"Worldwide epidemiology of paediatric multiple sclerosis: data from the multiple sclerosis international federation atlas of MS, third edition","author":"G Gombolay","year":"2025","journal-title":"J Neurol Neurosurg Psychiatry"},{"issue":"17","key":"ref2","first-page":"s321","article-title":"Impact of diagnosis and early treatment on the course of multiple sclerosis","volume":"19","author":"K Noyes","year":"2013","journal-title":"Am J Manag Care"},{"issue":"05","key":"ref3","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1016\/S2352-4642(24)00047-6","article-title":"Disease-modifying therapies in managing disability worsening in paediatric-onset multiple sclerosis: a longitudinal analysis of global and national registries","volume":"8","author":"S Sharmin","year":"2024","journal-title":"Lancet Child Adolesc Health"},{"issue":"01","key":"ref4","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1002\/ana.25737","article-title":"Real-world effectiveness of initial disease-modifying therapies in pediatric multiple sclerosis","volume":"88","author":"K M Krysko","year":"2020","journal-title":"Ann Neurol"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"105647","DOI":"10.1016\/j.msard.2024.105647","article-title":"Clinical and magnetic resonance imaging outcomes in pediatric-onset MS patients on fingolimod and ocrelizumab","volume":"87","author":"Z Nasr","year":"2024","journal-title":"Mult Scler Relat Disord"},{"issue":"26","key":"ref6","doi-asserted-by":"crossref","first-page":"2456","DOI":"10.1056\/NEJMp1802313","article-title":"Making neighborhood-disadvantage metrics accessible - the neighborhood atlas","volume":"378","author":"A JH Kind","year":"2018","journal-title":"N Engl J Med"},{"issue":"07","key":"ref7","doi-asserted-by":"crossref","first-page":"1379","DOI":"10.1016\/j.apmr.2021.12.028","article-title":"Healthcare disruptions and use of telehealth services among people with multiple sclerosis during the COVID-19 pandemic","volume":"103","author":"M H Chen","year":"2022","journal-title":"Arch Phys Med Rehabil"},{"issue":"10","key":"ref8","doi-asserted-by":"crossref","first-page":"6782","DOI":"10.1007\/s00415-024-12638-0","article-title":"Disability trajectories by progression independent of relapse activity status differ in pediatric, adult and late-onset multiple sclerosis","volume":"271","author":"M Simone","year":"2024","journal-title":"J Neurol"},{"issue":"11","key":"ref9","doi-asserted-by":"crossref","first-page":"e209991","DOI":"10.1212\/WNL.0000000000209991","article-title":"Epidemiology and impact of social hardships in children with multiple sclerosis in the United States","volume":"103","author":"E Wilson","year":"2024","journal-title":"Neurology"},{"issue":"05","key":"ref10","doi-asserted-by":"crossref","first-page":"e200282","DOI":"10.1212\/NXI.0000000000200282","article-title":"Early adversity and socioeconomic factors in pediatric multiple sclerosis: a case-control study","volume":"11","author":"S KG Jensen","year":"2024","journal-title":"Neurol Neuroimmunol Neuroinflamm"}],"container-title":["Neuropediatrics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-2650-6894.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T23:30:59Z","timestamp":1763076659000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-2650-6894"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,8]]},"references-count":10,"journal-issue":{"issue":"06","published-online":{"date-parts":[[2025,11,13]]},"published-print":{"date-parts":[[2025,12]]}},"URL":"https:\/\/doi.org\/10.1055\/a-2650-6894","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["0174-304X","1439-1899"],"issn-type":[{"value":"0174-304X","type":"print"},{"value":"1439-1899","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2025,7,8]]},"published":{"date-parts":[[2025,7,8]]}}}