{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T23:04:36Z","timestamp":1780009476045,"version":"3.53.1"},"reference-count":29,"publisher":"Georg Thieme Verlag KG","issue":"04","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Thorac Cardiovasc Surg"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Transcatheter mitral valve implantation (TMVI) is an evolving technology, expanding therapeutic options for patients at higher operative risk. Data comparing TMVI to surgical mitral valve replacement (SMVR) are lacking.<\/jats:p>\n                  <jats:p>Clinical outcomes after TMVI with the Tendyne mitral valve and SMVR were compared utilizing propensity score matching, including seven variables. The current study reports 1-year clinical outcomes after TMVI and 1-year mortality in both cohorts.<\/jats:p>\n                  <jats:p>Forty TMVI patients were compared to 80 SMVR patients. Baseline characteristics included in the matching protocol were well balanced: Age (78 years [interquartile range, IQR 75; 80] vs. 78 years [IQR 73; 80], p\u2009=\u20090.797), female sex (60% vs. 60% [p\u2009=\u20091.0]), atrial fibrillation (68% vs. 64% [p\u2009=\u20090.839]), previous coronary artery bypass grafting (CABG) or surgical aortic valve replacement (25% vs. 25% [p\u2009=\u20091.0]), body mass index (kg\/m2; 26\u2009\u00b1\u20094 vs. 25\u2009\u00b1\u20094 [p\u2009=\u20090.723]), mitral valve pathology (regurgitation 70% vs. 74%, stenosis 7.5% vs. 4%, and mixed disease 22.5% vs. 23% [p\u2009=\u20090.649]), and concomitant tricuspid regurgitation (35% vs. 30% [p\u2009=\u20090.678]). Thirty-day mortality was similar in both groups (TMVI, n\u2009=\u20091, 2.5%; SMVR, n\u2009=\u20093, 3.75%, p\u2009=\u20090.47). Kaplan\u2013Meier estimated survival at 1 year was comparable after TMVI (80\u2009\u00b1\u20096% [95% CI 69\u201393%]) and SMVR (86\u2009\u00b1\u20094% [95% CI 79\u201394%], p\u2009=\u20090.18) with seven additional deaths beyond 30 days in the TMVI group and eight in the SMVR group. In the TMVI group, two were non-cardiovascular deaths for encephalitis and sepsis after hip replacement, and five were cardiovascular deaths. In the SMVR group, one patient died due to intestinal ischemia, and in seven patients, the cause of death is unknown. At 1 year, in all TMVI patients, echocardiography showed \u2264mild paravalvular regurgitation. Within 1 year after TMVI, 21 patients (52.5%) required rehospitalization for heart failure symptoms.<\/jats:p>\n                  <jats:p>TMVI and SMVR in a propensity score-matched cohort displaying an intermediate surgical risk resulted in similar 1-year survival. TMVI achieved a sustained MR elimination at 1 year, and 80% of patients presented in the New York Heart Association (NYHA) class I or II.<\/jats:p>","DOI":"10.1055\/a-2650-7092","type":"journal-article","created":{"date-parts":[[2025,7,18]],"date-time":"2025-07-18T23:22:57Z","timestamp":1752880977000},"page":"316-323","source":"Crossref","is-referenced-by-count":1,"title":["Transcatheter Mitral Valve Implantation Compared to Surgery: One-Year Clinical Outcome"],"prefix":"10.1055","volume":"74","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6886-3660","authenticated-orcid":false,"given":"Hendrik","family":"Ruge","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Institute Insure, German Heart Centre Munich, School of Medicine and Health, Technical University of Munich, Munich, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8540-7090","authenticated-orcid":false,"given":"Melchior","family":"Burri","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Institute Insure, German Heart Centre Munich, School of Medicine and Health, Technical University of Munich, Munich, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7560-9257","authenticated-orcid":false,"given":"Magdalena","family":"Erlebach","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Institute Insure, German Heart Centre Munich, School of Medicine and Health, Technical University of Munich, Munich, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8685-532X","authenticated-orcid":false,"given":"Stephanie S.","family":"Voss","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Institute Insure, German Heart Centre Munich, School of Medicine and Health, Technical University of Munich, Munich, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nazan","family":"Puluca","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Institute Insure, German Heart Centre Munich, School of Medicine and Health, Technical University of Munich, Munich, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caterina","family":"Campanella","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Institute Insure, German Heart Centre Munich, School of Medicine and Health, Technical University of Munich, Munich, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felix","family":"Wirth","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Institute Insure, German Heart Centre Munich, School of Medicine and Health, Technical University of Munich, Munich, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erion","family":"Xhepa","sequence":"additional","affiliation":[{"name":"Department of Cardiology, German Heart Centre Munich, School of Medicine and Health, Technical University of Munich, Munich, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Stein","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology, German Heart Centre Munich, School of Medicine and Health, Technical University of Munich, Munich, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Markus","family":"Krane","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Institute Insure, German Heart Centre Munich, School of Medicine and Health, Technical University of Munich, Munich, Germany"},{"name":"German Centre for Cardiovascular Research (DZHK)-Partner Site Munich Heart Alliance, Munich, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2025,7,18]]},"reference":[{"issue":"24","key":"ref1","doi-asserted-by":"crossref","first-page":"2307","DOI":"10.1056\/NEJMoa1806640","article-title":"Transcatheter mitral-valve repair in patients with heart failure","volume":"379","author":"G W Stone","year":"2018","journal-title":"N Engl J Med"},{"issue":"15","key":"ref2","doi-asserted-by":"crossref","first-page":"1395","DOI":"10.1056\/NEJMoa1009355","article-title":"Percutaneous repair or surgery for mitral regurgitation","volume":"364","author":"T Feldman","year":"2011","journal-title":"N Engl J Med"},{"issue":"19","key":"ref3","doi-asserted-by":"crossref","first-page":"1787","DOI":"10.1056\/NEJMoa2408739","article-title":"Transcatheter repair versus mitral-valve surgery for secondary mitral 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