{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,28]],"date-time":"2025-11-28T08:35:56Z","timestamp":1764318956691,"version":"3.46.0"},"reference-count":28,"publisher":"Georg Thieme Verlag KG","issue":"S 01","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Zentralbl Chir"],"published-print":{"date-parts":[[2025,8]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title>\n                  <jats:p>Wenn die konservative Therapie einer COPD mit Lungenemphysem ausgereizt ist und eine Lungentransplantation nicht infrage kommt, kann eine Reduktion des Lungenvolumens der n\u00e4chste Therapieschritt sein. Lungenvolumenreduktionschirurgie (Lung Volume Reduction Surgery, LVRS) verwendet unterschiedliche Techniken, u.\u00a0a. das sog. \u201eapikale Shaving\u201c, die gezielte Resektion einer Targetzone und die vollst\u00e4ndige Lappenresektion. Neben diesen LVRS-Techniken besteht die M\u00f6glichkeit einer minimalinvasiven, bronchoskopisch gef\u00fchrten Therapie mit Einbahnstra\u00dfenventilen, endobronchialen Coils oder Wasserdampfablation. Allen chirurgischen und bronchoskopischen Verfahren gemein ist die Notwendigkeit einer kritischen Patientenselektion und einer aussagekr\u00e4ftigen radiologischen Diagnostik zur Therapieplanung. Dazu geh\u00f6ren die Akquise eines computertomografischen Volumendatensatzes der Lunge, die softwareunterst\u00fctzte Quantifizierung des Emphysemanteils am Lungengewebe und die Beurteilung der Fissurenintegrit\u00e4t. Vor allem bei komplexen Befundkonstellationen k\u00f6nnen nuklearmedizinische Untersuchungen wertvolle Zusatzinformationen liefern. Die interdisziplin\u00e4re Emphysemkonferenz entscheidet dann unter W\u00fcrdigung s\u00e4mtlicher Vordiagnostik, welcher Patient welchem Therapieverfahren zugef\u00fchrt werden soll.<\/jats:p>","DOI":"10.1055\/a-2654-6206","type":"journal-article","created":{"date-parts":[[2025,8,25]],"date-time":"2025-08-25T22:39:14Z","timestamp":1756161554000},"page":"S28-S38","source":"Crossref","is-referenced-by-count":0,"special_numbering":"S","title":["Radiologische Aspekte der Lungenvolumenreduktionschirurgie"],"prefix":"10.1055","volume":"150","author":[{"given":"Jan Philipp","family":"Hering","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Radiologie und Neuroradiologie, Klinikum Ibbenb\u00fcren gGmbH, Ibbenb\u00fcren, Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aron","family":"Elsner","sequence":"additional","affiliation":[{"name":"Thoraxchirurgie, Charit\u00e9 Universit\u00e4tsmedizin Berlin, Campus Charit\u00e9 Mitte, Berlin, Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Felix","family":"D\u00f6llinger","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Radiologie, Charit\u00e9 - Universit\u00e4tsmedizin Berlin, Berlin, Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2025,8,25]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"203","DOI":"10.1016\/j.thorsurg.2021.02.007","article-title":"Lung Volume Reduction Surgery in Patients with Homogeneous Emphysema","volume":"31","author":"W Weder","year":"2021","journal-title":"Thorac Surg Clin"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"434","DOI":"10.3238\/arztebl.m2023.0027","article-title":"The diagnosis and treatment of COPD and its comorbidities","volume":"120","author":"K Kahnert","year":"2023","journal-title":"Dtsch Arztebl Int"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2018172294","article-title":"CT-based Visual Classification of Emphysema: Association with Mortality in the COPDGene Study","volume":"288","author":"DA Lynch","year":"2018","journal-title":"Radiology"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"192","DOI":"10.1148\/radiol.2015141579","article-title":"CT-Definable Subtypes of Chronic Obstructive Pulmonary Disease: A Statement of the Fleischner Society","volume":"277","author":"DA Lynch","year":"2015","journal-title":"Radiology"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"2059","DOI":"10.1056\/nejmoa030287","article-title":"A Randomized Trial Comparing Lung-Volume-Reduction Surgery with Medical Therapy for Severe Emphysema","volume":"348","author":"A Fishman","year":"2003","journal-title":"N Engl J Med"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"510","DOI":"10.1007\/s00330-007-0772-1","article-title":"Morphological and functional imaging in COPD with CT and MRI: present and future","volume":"18","author":"J Ley-Zaporozhan","year":"2008","journal-title":"Eur Radiol"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1097\/rti.0b013e3181b32676","article-title":"Chronic obstructive pulmonary disease: radiology-pathology correlation","volume":"24","author":"SNJ Pipavath","year":"2009","journal-title":"J Thorac Imag"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"653","DOI":"10.1164\/ajrccm.152.2.7633722","article-title":"Comparison of computed density and macroscopic morphometry in pulmonary emphysema","volume":"152","author":"PA Gevenois","year":"1995","journal-title":"Am J Respir Crit Care Med"},{"issue":"S 23","key":"ref10","doi-asserted-by":"publisher","first-page":"S2719","DOI":"10.21037\/jtd.2018.05.117","article-title":"Emphysema and lung volume reduction: the role of radiology","volume":"10","author":"K Martini","year":"2018","journal-title":"J Thorac Dis"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"1354","DOI":"10.1164\/rccm.201902-0383oc","article-title":"Improving Lung Function in Severe Heterogenous Emphysema with the Spiration Valve System (EMPROVE). A Multicenter, Open-Label Randomized Controlled Clinical Trial","volume":"200","author":"GJ Criner","year":"2019","journal-title":"Am J Resp Crit Care"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"150","DOI":"10.1159\/000448849","article-title":"Predicting Lung Volume Reduction after Endobronchial Valve Therapy Is Maximized Using a Combination of Diagnostic Tools","volume":"92","author":"TD Koster","year":"2016","journal-title":"Respiration"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"369","DOI":"10.1007\/s00117-019-0509-6","article-title":"Bildgebung vor und nach endoskopischer Lungenvolumenreduktion","volume":"59","author":"F Doellinger","year":"2019","journal-title":"Radiologe"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"1467","DOI":"10.21037\/atm.2020.04.44","article-title":"Advances in imaging for lung emphysema","volume":"8","author":"K Martini","year":"2020","journal-title":"Ann Transl Med"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1053\/j.semnuclmed.2018.10.010","article-title":"Lung Scintigraphy in COPD","volume":"49","author":"J Mortensen","year":"2019","journal-title":"Semin Nucl Med"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"1622","DOI":"10.1007\/s11547-024-01883-y","article-title":"Pulmonary emphysema: the assessment of lung perfusion with Dual-Energy CT and pulmonary scintigraphy","volume":"129","author":"A Borgheresi","year":"2024","journal-title":"Radiol Med"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"509","DOI":"10.1055\/a-2452-0288","article-title":"Photon-Counting Detector CT: Advances and Clinical Applications in Cardiovascular Imaging","volume":"197","author":"MT Hagar","year":"2024","journal-title":"RoFo"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"112","DOI":"10.3390\/jimaging8040112","article-title":"Spectral Photon-Counting Computed Tomography: A Review on Technical Principles and Clinical Applications","volume":"8","author":"M Tortora","year":"2022","journal-title":"J Imaging"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.230318","article-title":"Regional Pulmonary Morphology and Function: Photon-counting CT Assessment","volume":"308","author":"SC Scharm","year":"2023","journal-title":"Radiology"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"7831","DOI":"10.1007\/s00330-024-10888-0","article-title":"Image quality of lung perfusion with photon-counting-detector CT: comparison with dual-source, dual-energy CT","volume":"34","author":"M Remy-Jardin","year":"2024","journal-title":"Eur Radiol"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"1122","DOI":"10.1002\/jmri.26342","article-title":"Comparison of quantitative regional perfusion-weighted phase resolved functional lung (PREFUL) MRI with dynamic gadolinium-enhanced regional pulmonary perfusion MRI in COPD patients","volume":"49","author":"TF Kaireit","year":"2019","journal-title":"J Magn Reson Imaging"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"313","DOI":"10.1002\/jmri.23844","article-title":"Hyperpolarized 129Xe MRI of the human lung","volume":"37","author":"JP Mugler","year":"2013","journal-title":"J Magn Reson Imaging"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"823","DOI":"10.1007\/s00117-020-00730-1","article-title":"Detektion von Lungenver\u00e4nderungen bei Patienten mit Mukoviszidose: Innovationen der Magnetresonanztomographie des Thorax","volume":"60","author":"S Nyilas","year":"2020","journal-title":"Radiologe"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"264","DOI":"10.1007\/s10405-022-00462-0","article-title":"Nichtinvasive funktionelle Lungenbildgebung mit hyperpolarisiertem Xenon","volume":"19","author":"M Anikeeva","year":"2022","journal-title":"Z Pneumologie"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"2107","DOI":"10.1002\/mrm.26310","article-title":"Reproducibility of quantitative indices of lung function and microstructure from 129Xe chemical shift saturation recovery (CSSR) MR spectroscopy","volume":"77","author":"NJ Stewart","year":"2017","journal-title":"Magn Reson Med"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"1398","DOI":"10.1152\/japplphysiol.00702.2020","article-title":"Using hyperpolarized 129Xe gas-exchange MRI to model the regional airspace, membrane, and capillary contributions to diffusing capacity","volume":"130","author":"Z Wang","year":"2021","journal-title":"J Appl Physiol"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.3791\/66380","article-title":"Phase-resolved Functional Lung MRI for Pulmonary Ventilation and Perfusion (V\/Q) Assessment","author":"A Voskrebenzev","year":"2024","journal-title":"J Vis Exp"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"2306","DOI":"10.1002\/mrm.26893","article-title":"Feasibility of quantitative regional ventilation and perfusion mapping with phase-resolved functional lung (PREFUL) MRI in healthy volunteers and COPD, CTEPH, and CF patients","volume":"79","author":"A Voskrebenzev","year":"2018","journal-title":"Magn Reson Med"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1148\/ryct.210147","article-title":"PREFUL MRI Depicts Dual Bronchodilator Changes in COPD: A Retrospective Analysis of a Randomized Controlled Trial","volume":"4","author":"A Voskrebenzev","year":"2022","journal-title":"Radiol: Cardiothorac Imaging"}],"container-title":["Zentralblatt f\u00fcr Chirurgie - Zeitschrift f\u00fcr Allgemeine, Viszeral-, Thorax- und Gef\u00e4\u00dfchirurgie"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-2654-6206.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,28]],"date-time":"2025-11-28T08:31:56Z","timestamp":1764318716000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-2654-6206"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8]]},"references-count":28,"journal-issue":{"issue":"S 01","published-online":{"date-parts":[[2025,8,25]]},"published-print":{"date-parts":[[2025,8]]}},"URL":"https:\/\/doi.org\/10.1055\/a-2654-6206","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["0044-409X","1438-9592"],"issn-type":[{"type":"print","value":"0044-409X"},{"type":"electronic","value":"1438-9592"}],"subject":[],"published":{"date-parts":[[2025,8]]}}}