{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T21:35:26Z","timestamp":1757626526257,"version":"3.44.0"},"reference-count":42,"publisher":"Georg Thieme Verlag KG","issue":"03","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Semin Respir Crit Care Med"],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Neuromuscular diseases encompass a wide array of clinical manifestations, age at presentation, and severity of morbidity and mortality. Central to most patients with these disorders are symptoms of dyspnea and increased work of breathing related to varying degrees of impairment of the neuromuscular apparatus. The degree of dyspnea is often compounded by impaired clearance from the tracheobronchial tree, leading to patients who are weak, dyspneic, and impacted by pulmonary secretions. Approaches to determining contributing causes and management of dyspnea in these patients vary among adult and pediatric patients and are also distinct depending on the natural progression of the specific neuromuscular disorder. We describe an approach to the management of dyspnea in patients with neuromuscular diseases and review the roles of pharmacologic and respiratory support devices in alleviating symptoms and supporting respiration.<\/jats:p>","DOI":"10.1055\/a-2657-9524","type":"journal-article","created":{"date-parts":[[2025,8,14]],"date-time":"2025-08-14T23:00:31Z","timestamp":1755212431000},"page":"288-294","source":"Crossref","is-referenced-by-count":0,"title":["Management of Dyspnea in Patients with Neuromuscular Disorders"],"prefix":"10.1055","volume":"46","author":[{"given":"Daniel","family":"Scullin","sequence":"additional","affiliation":[{"name":"Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph","family":"Barney","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2025,8,14]]},"reference":[{"issue":"11","key":"ref1","first-page":"1239","article-title":"Health care resource utilization and costs across stages of amyotrophic lateral sclerosis in the United States","volume":"30","author":"K Stenson","year":"2024","journal-title":"J Manag Care Spec Pharm"},{"issue":"02","key":"ref2","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1007\/s00455-022-10503-8","article-title":"Predictors of peak expiratory cough flow in individuals with amyotrophic lateral sclerosis","volume":"38","author":"L Tabor Gray","year":"2023","journal-title":"Dysphagia"},{"issue":"01","key":"ref3","doi-asserted-by":"crossref","first-page":"10513","DOI":"10.1038\/s41598-025-94844-y","article-title":"Autonomic nervous system and mediating role of respiratory function in patients with ALS","volume":"15","author":"N de Bernardo","year":"2025","journal-title":"Sci Rep"},{"volume-title":"Diaphragm Disorders","year":"2025","author":"L Kokatnur","key":"ref4"},{"issue":"04","key":"ref5","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1016\/j.jsmc.2020.08.004","article-title":"Noninvasive ventilation in amyotrophic lateral sclerosis","volume":"15","author":"J A Cooksey","year":"2020","journal-title":"Sleep Med Clin"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"838414","DOI":"10.3389\/fphys.2022.838414","article-title":"Methods and applications in respiratory physiology: Respiratory mechanics, drive and muscle function in neuromuscular and chest wall disorders","volume":"13","author":"N Patel","year":"2022","journal-title":"Front Physiol"},{"issue":"01","key":"ref7","first-page":"51","article-title":"Daytime alternatives for non-invasive mechanical ventilation in neuromuscular disorders","volume":"40","author":"A Annunziata","year":"2021","journal-title":"Acta Myol"},{"issue":"12","key":"ref8","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1016\/j.arbr.2014.06.025","article-title":"Complementary home mechanical ventilation techniques. 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