{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,28]],"date-time":"2025-11-28T08:35:57Z","timestamp":1764318957214,"version":"3.46.0"},"reference-count":32,"publisher":"Georg Thieme Verlag KG","issue":"S 01","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Zentralbl Chir"],"published-print":{"date-parts":[[2025,8]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title>\n                  <jats:p>Die CT-gesteuerte transthorakale Lungenbiopsie (CT-TTNB) ist eine essenzielle Methode\n\t\t\tzur Diagnostik pulmonaler Rundherde und Raumforderungen. Mit einer Sensitivit\u00e4t von\n\t\t\t85\u201397% und einer Spezifit\u00e4t von 85\u2013100% bietet sie eine hohe diagnostische Genauigkeit.\n\t\t\tDurch den Einsatz von Core-Needle-Biopsien k\u00f6nnen qualitativ hochwertige Gewebeproben\n\t\t\tgewonnen werden, die molekulare Analysen f\u00fcr eine personalisierte Therapie\n\t\t\term\u00f6glichen.Parallel hat sich die Lungenablation als wertvolle minimalinvasive\n\t\t\tTherapie etabliert. Verfahren wie Radiofrequenzablation (RFA), Mikrowellenablation (MWA)\n\t\t\tund Kryoablation erm\u00f6glichen eine gezielte Tumorzerst\u00f6rung, insbesondere bei inoperablen\n\t\t\tPatienten mit NSCLC oder Lungenmetastasen. Studien belegen eine hohe lokale\n\t\t\tTumorkontrolle bei akzeptablen Komplikationsraten. Die Kombination aus Bildgebung und\n\t\t\tinterventioneller Technik bietet gute Ergebnisse bei niedrigen\n\t\t\tKomplikationsraten.Insgesamt sind CT-gesteuerte Punktion und Ablation integrale\n\t\t\tBestandteile der modernen Diagnostik bei prim\u00e4ren und sekund\u00e4ren Lungentumoren, und\n\t\t\tbietet gleichzeitig eine neue Therapieoption. Sie bieten pr\u00e4zise, risikoarme\n\t\t\tAlternativen zu invasiven Verfahren und tragen k\u00f6nnen daher zu einer effektiven\n\t\t\tPatientenversorgung beitragen.<\/jats:p>","DOI":"10.1055\/a-2665-4806","type":"journal-article","created":{"date-parts":[[2025,8,25]],"date-time":"2025-08-25T22:39:14Z","timestamp":1756161554000},"page":"S50-S57","source":"Crossref","is-referenced-by-count":0,"special_numbering":"S","title":["M\u00f6glichkeiten und Limitationen der CT-gesteuerten Intervention"],"prefix":"10.1055","volume":"150","author":[{"given":"Marco","family":"Das","sequence":"additional","affiliation":[{"name":"Diagnostische und Interventionelle Radiologie, HELIOS St. Johannes Klinik Duisburg, Duisburg, Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2025,8,25]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"138","DOI":"10.1007\/s00330-016-4357-8","article-title":"Complication rates of 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