{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T22:14:31Z","timestamp":1787004871802,"version":"build-2736575974"},"reference-count":318,"publisher":"Georg Thieme Verlag KG","issue":"11","license":[{"start":{"date-parts":[[2025,11,10]],"date-time":"2025-11-10T00:00:00Z","timestamp":1762732800000},"content-version":"vor","delay-in-days":9,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Z Gastroenterol"],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title>\n                  <jats:p>Portale Hypertonie ist mit erheblicher Morbidit\u00e4t und Mortalit\u00e4t verbunden. Die Leberzirrhose macht bis zu 90\u200a% der F\u00e4lle von portaler Hypertonie aus, w\u00e4hrend etwa 10\u200a% auf nicht-zirrhotische Faktoren, einschlie\u00dflich vaskul\u00e4rer Lebererkrankungen, zur\u00fcckzuf\u00fchren sind.<\/jats:p>\n                  <jats:p>Diese Erkrankung kann zu schweren Komplikationen f\u00fchren, wie der Entwicklung von gastro\u00f6sophagealen Varizen, die das Risiko von varik\u00f6sen Blutungen erheblich erh\u00f6hen. Weitere h\u00e4ufige Komplikationen der portalen Hypertonie sind Aszites und hepatorenales Syndrom (HRS).<\/jats:p>\n                  <jats:p>Eine transjugul\u00e4re intrahepatische portosystemische Shunt (TIPS)-Implantation wird als die effektivste Behandlung zur Bew\u00e4ltigung der portalen Hypertonie angesehen. Studien zeigen, dass die TIPS-Implantation die \u00dcberlebensraten bei Patienten mit wiederkehrendem Aszites sowie bei ausgew\u00e4hlten Patienten mit refrakt\u00e4rem Aszites und varik\u00f6sen Blutungen verbessern kann. Allerdings k\u00f6nnen periinterventionelle und postinterventionelle Komplikationen die Anwendung von TIPS einschr\u00e4nken. Neueste Entwicklungen bei Ger\u00e4ten, Techniken und prophylaktischen Medikamenten zielen darauf ab, das Risiko von Komplikationen nach dem Eingriff zu minimieren.<\/jats:p>\n                  <jats:p>Dieses interdisziplin\u00e4re Positionspapier fasst Empfehlungen und Anleitung zur Patientenwahl, zu Indikationen und Kontraindikationen, zu Techniken sowie zur Nachsorge von Patienten zusammen, die in Deutschland ein TIPS-Verfahren erhalten.<\/jats:p>","DOI":"10.1055\/a-2675-4735","type":"journal-article","created":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T00:21:07Z","timestamp":1762820467000},"page":"1149-1181","source":"Crossref","is-referenced-by-count":2,"title":["Positionspapier f\u00fcr die standardisierte Anwendung von Transjugul\u00e4rem Intrahepatischem Portosystemischem Shunt (TIPS) bei Erwachsenen"],"prefix":"10.1055","volume":"63","author":[{"given":"Jonel","family":"Trebicka","sequence":"additional","affiliation":[{"name":"Medizinische Klinik B (Gastroenterologie, Hepatologie, Endokrinologie, Klinische Infektiologie), Universit\u00e4tsklinikum M\u00fcnster, M\u00fcnster"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Steib","sequence":"additional","affiliation":[{"name":"Internistisches Klinikum M\u00fcnchen S\u00fcd, Klinik f\u00fcr Gastroenterologie und Innere Medizin, M\u00fcnchen"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Zipprich","sequence":"additional","affiliation":[{"name":"Innere Medizin IV (Gastroenterologie, Hepatologie, Infektiologie, interdisziplin\u00e4re Endoskopie), Universit\u00e4tsklinikum Jena, FSU Jena, Jena"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristina","family":"Ripoll","sequence":"additional","affiliation":[{"name":"Innere Medizin IV (Gastroenterologie, Hepatologie, Infektiologie, interdisziplin\u00e4re Endoskopie), Universit\u00e4tsklinikum Jena, FSU Jena, Jena"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johannes","family":"Kluwe","sequence":"additional","affiliation":[{"name":"Medizinische Klinik und Poliklinik, Universit\u00e4tsklinikum Hamburg-Eppendorf, Hamburg"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Schulthei\u00df","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Innere Medizin II, Universit\u00e4tsklinikum Freiburg, Medizinische Fakult\u00e4t, Albert-Ludwigs-Universit\u00e4t Freiburg, Deutschland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas A.","family":"Schnitzbauer","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Chirurgie, Universit\u00e4tsklinikum Regensburg, Regensburg"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernhard","family":"Meyer","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Diagnostische und Interventionelle Radiologie, Medizinische Hochschule Hannover, Hannover"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Jansen","sequence":"additional","affiliation":[{"name":"Medizinische Klinik I, Universit\u00e4tsklinikum Bonn, Bonn"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hauke","family":"Heinzow","sequence":"additional","affiliation":[{"name":"Medizinische Klinik B (Gastroenterologie, Hepatologie, Endokrinologie, Klinische Infektiologie), Universit\u00e4tsklinikum M\u00fcnster, M\u00fcnster"},{"name":"Medizinische Klinik I, Krankenhaus der Barmherzigen Br\u00fcder, Trier, Abteilung f\u00fcr Interventionelle Radiologie, Klinikum rechts der Isar der Technischen Universit\u00e4t M\u00fcnchen, M\u00fcnchen"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philipp","family":"Papprottka","sequence":"additional","affiliation":[{"name":"Abteilung f\u00fcr Interventionelle Radiologie, Klinikum rechts der Isar der Technischen Universit\u00e4t M\u00fcnchen, M\u00fcnchen"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carsten","family":"Meyer","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Diagnostische und Interventionelle Radiologie Universit\u00e4tsklinikum Bonn"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Max","family":"Seidensticker","sequence":"additional","affiliation":[{"name":"Klinik und Poliklinik f\u00fcr Radiologie, Universit\u00e4tsklinikum, LMU Klinikum, M\u00fcnchen"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harald","family":"Ittrich","sequence":"additional","affiliation":[{"name":"Abteilung f\u00fcr Diagnostische und Interventionelle Radiologie, Sch\u00f6n Klinik Hamburg SE & KO. 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