{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,17]],"date-time":"2025-10-17T23:10:56Z","timestamp":1760742656771,"version":"build-2065373602"},"reference-count":27,"publisher":"Georg Thieme Verlag KG","issue":"09","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Exp Clin Endocrinol Diabetes"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>To assess the necessity of additional imaging by comparing the\n                        characteristics of adrenal lesions incidentally detected on abdominal, stone\n                        protocol, and chest computed tomography (CT) with those obtained from a\n                        second imaging modality specifically targeting the adrenal glands.<\/jats:p><jats:p>A total of 162 adrenal lesions imaged in 112 patients with adrenal\n                        incidentalomas were retrospectively analyzed. Radiology reports were\n                        reviewed for adrenal lesion laterality, location, number of lesions, maximum\n                        diameter, the number of dimensions specified, lesion density on CT measured\n                        in Hounsfield Units (HU), lesion characterization, presence of\n                        heterogeneity, and functional status. Cohen\u2019s Kappa test assessed the\n                        agreement between the first and second imaging evaluations. Additionally,\n                        sensitivity, specificity, positive predictive value, and negative predictive\n                        value of the first imaging were calculated using adrenal-specific second\n                        imaging as the reference standard.<\/jats:p><jats:p>No concordance was found between the initial and follow-up imaging in terms\n                        of HU measurements (\u03ba=0.079; p=0.123). However, concordance ranging from\n                        weak to excellent was observed regarding bilaterality, localization, lesion\n                        count, diameter, and heterogeneity. Based on the second imaging reports as\n                        reference, the sensitivity of the initial imaging for diagnosing adenoma and\n                        myelolipoma was determined to be 26.49% and 42.85%, respectively. The\n                        success rate of adenoma diagnosis was associated with the number of lesions\n                        in the adrenal gland (\u22652 lesions&gt;single lesion), lesion size (&gt;2\n                        cm&gt;\u2264\u20092 cm), and location (left&gt;right). Nine lesions initially reported\n                        as&lt;4 cm on the first imaging were found to be\u22654 cm on the second imaging,\n                        and seven lesions initially reported as unilateral were noted to be\n                        bilateral on the second imaging. In eight patients, adrenal lesions were\n                        detected on the first imaging, but the second imaging was reported as\n                        normal.<\/jats:p><jats:p>A more detailed definition of adrenal incidentalomas, especially in terms of\n                        heterogeneity and HU values in the first images in radiology reports, and\n                        the use of a standard reporting system will guide clinical practice and\n                        provide a cost-effective approach while avoiding unnecessary imaging and\n                        radiation.<\/jats:p>","DOI":"10.1055\/a-2676-0950","type":"journal-article","created":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T23:01:22Z","timestamp":1759359682000},"page":"453-461","source":"Crossref","is-referenced-by-count":0,"title":["The Effect of Radiological Imaging Reports in Clinical\n                    Decision-Making in the Management of Adrenal Incidentaloma"],"prefix":"10.1055","volume":"133","author":[{"given":"Puren","family":"G\u00f6kbulut","sequence":"additional","affiliation":[{"name":"Ankara Training and Research Hospital, Ankara, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cagatay Emir","family":"Onder","sequence":"additional","affiliation":[{"name":"Ankara Training and Research Hospital, Ankara, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Serife Mehlika","family":"Kuskonmaz","sequence":"additional","affiliation":[{"name":"Ankara Training and Research Hospital, Ankara, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2025,10,1]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"G1","DOI":"10.1093\/ejendo\/lvad066.","article-title":"European Society of Endocrinology clinical practice guidelines on the management\n                    of adrenal incidentalomas, in collaboration with the European Network for the\n                    Study of Adrenal Tumors","volume":"189","author":"M Fassnacht","year":"2023","journal-title":"Eur J Endocrinol"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"231","DOI":"10.1016\/j.amjsurg.2021.06.015.","article-title":"Radiology report language positively influences adrenal incidentaloma guideline\n                    adherence","volume":"223","author":"J Watari","year":"2022","journal-title":"Am J Surg"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"3736","DOI":"10.3390\/cancers15143736","article-title":"An integrated CT and MRI imaging model to differentiate between adrenal adenomas\n                    and pheochromocytomas","volume":"15","author":"M Araujo-Castro","year":"2023","journal-title":"Cancers"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"1319","DOI":"10.1148\/rg.295095026","article-title":"Adrenal imaging with multidetector CT: Evidence-based protocol optimization and\n          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Israel","year":"2004","journal-title":"AJR Am J Roentgenol"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"200","DOI":"10.3803\/EnM.2017.32.2.200","article-title":"Clinical guidelines for the management of adrenal incidentaloma","volume":"32","author":"Korean Endocrine Society, Committee for Clinical Practice\n                            Guidelines","year":"2017","journal-title":"Endocrinol Metab"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"590","DOI":"10.1097\/JU.0000000000003644","article-title":"Diagnosis, management, and follow-up of the incidentally discovered adrenal\n                    mass: CUA guideline endorsed by the AUA","volume":"210","author":"N E Rowe","year":"2023","journal-title":"J Urol"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"52","DOI":"10.1097\/JU.0000000000001342","article-title":"Discrepancies in the recommended management of adrenal incidentalomas by various\n                    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Guideline","volume":"101","author":"J W Funder","year":"2016","journal-title":"J Clin Endocrinol Metab"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"4113","DOI":"10.1210\/jc.2018-01394.","article-title":"Comparison of seated with recumbent saline suppression testing for the diagnosis\n                    of primary aldosteronism","volume":"103","author":"M Stowasser","year":"2018","journal-title":"J Clin Endocrinol Metab"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"12","DOI":"10.5489\/cuaj.8248","article-title":"Canadian Urological Association guideline: Diagnosis, management, and follow-up\n                    of the incidentally discovered adrenal mass","volume":"17","author":"N E Rowe","year":"2023","journal-title":"Can Urol Assoc J"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"1","DOI":"10.4158\/EP.15.S1.1","article-title":"The American Association of Clinical Endocrinologists and American Association\n                    of Endocrine 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In: StatPearls [Internet]","year":"2024","author":"E Mahmood","key":"ref27"}],"container-title":["Experimental and Clinical Endocrinology &amp; Diabetes"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-2676-0950.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,17]],"date-time":"2025-10-17T22:41:30Z","timestamp":1760740890000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-2676-0950"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9]]},"references-count":27,"journal-issue":{"issue":"09","published-online":{"date-parts":[[2025,10,17]]},"published-print":{"date-parts":[[2025,9]]}},"URL":"https:\/\/doi.org\/10.1055\/a-2676-0950","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["0947-7349","1439-3646"],"issn-type":[{"type":"print","value":"0947-7349"},{"type":"electronic","value":"1439-3646"}],"subject":[],"published":{"date-parts":[[2025,9]]}}}