{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T22:54:47Z","timestamp":1791586487970,"version":"4.3.4"},"reference-count":31,"publisher":"Georg Thieme Verlag KG","issue":"05","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ultraschall Med"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>In cases of severe or refractory carpal tunnel syndrome (CTS), carpal tunnel release (CTR) can be performed using open surgery, endoscopic techniques, or minimally invasive approaches under high-resolution ultrasound (HRUS) guidance. This study aimed to evaluate the long-term clinical outcomes following HRUS-guided CTR.<\/jats:p>\n                  <jats:p>A retrospective analysis was conducted on 302 HRUS-CTR cases. Patients who were available for a phone interview and had a minimum follow-up period of one year were assessed using the Boston Carpal Tunnel Questionnaire (BCTQ). Symptom severity and functional limitations were compared before and after the procedure.<\/jats:p>\n                  <jats:p>Of the 302 cases screened, 111 cases had to be excluded due to unavailability for the phone call, missing data, or death. Accordingly, 191 cases were included. The average patient age was 60.4 \u00b1 15.5 years (range: 19 to 87 years). 126 cases (66%) were female and 65 cases (34.0%) were male. Overall, there was a significant reduction of 91.9% in CTS-related symptom severity and frequency for all items recorded in the questionnaire. Similarly, a significant reduction of 84.8% in difficulty with all self-reported daily activities was found. In addition, the procedures were performed by four physicians showing no significant differences in technical success and symptoms reduction.<\/jats:p>\n                  <jats:p>HRUS-CTR is a safe and effective method for the treatment of CTS, showing a statistically but mostly clinically significant reduction in symptom severity and hand discomfort, which persisted 1 year after release and should therefore be considered as an alternative approach to open or endoscopic CTR.<\/jats:p>","DOI":"10.1055\/a-2678-8214","type":"journal-article","created":{"date-parts":[[2025,8,7]],"date-time":"2025-08-07T23:20:52Z","timestamp":1754608852000},"page":"493-498","source":"Crossref","is-referenced-by-count":1,"title":["Minimally invasive ultrasound-guided carpal tunnel release: long-term clinical outcomes"],"prefix":"10.1055","volume":"47","author":[{"given":"Sarah","family":"Honold","sequence":"additional","affiliation":[{"name":"Medical University Innsbruck, Austria","place":["Innsbruck"],"department":["Department of Radiology"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Loizides","sequence":"additional","affiliation":[{"name":"Medical University Innsbruck, Austria","place":["Innsbruck"],"department":["Department of Radiology"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisabeth","family":"Skalla","sequence":"additional","affiliation":[{"name":"Medical University Innsbruck, Austria","place":["Innsbruck"],"department":["Department of Radiology"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leonhard","family":"Gruber","sequence":"additional","affiliation":[{"name":"Medical University Innsbruck, Austria","place":["Innsbruck"],"department":["Department of Radiology"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michaela","family":"Plaikner","sequence":"additional","affiliation":[{"name":"Medical University Innsbruck, Austria","place":["Innsbruck"],"department":["Department of Radiology"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hannes","family":"Gruber","sequence":"additional","affiliation":[{"name":"Medical University Innsbruck, Austria","place":["Innsbruck"],"department":["Department of Radiology"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2025,9,8]]},"reference":[{"issue":"01","key":"ref1","doi-asserted-by":"publisher","first-page":"146","DOI":"10.1016\/j.ejrad.2007.06.017","article-title":"Sonography and electrodiagnosis in carpal tunnel syndrome diagnosis, an analysis of the literature","volume":"67","author":"P Seror","year":"2008","journal-title":"Eur J Radiol"},{"issue":"03","key":"ref2","doi-asserted-by":"publisher","first-page":"243","DOI":"10.1007\/s10072-009-0213-9","article-title":"Diagnosis, treatment and follow-up of the carpal tunnel syndrome: a review","volume":"31","author":"C Alfonso","year":"2010","journal-title":"NeurolSci"},{"issue":"03","key":"ref3","doi-asserted-by":"publisher","first-page":"242","DOI":"10.1055\/s-0031-1273309","article-title":"Diagnostic sonography of peripheral nerves: indications, examination techniques and pathological findings","volume":"32","author":"H Kopf","year":"2011","journal-title":"Ultraschall Med"},{"issue":"03","key":"ref4","doi-asserted-by":"publisher","first-page":"273","DOI":"10.1080\/17434440.2022.2048816","article-title":"Multicenter pragmatic study of carpal tunnel release with ultrasound guidance","volume":"19","author":"JR Fowler","year":"2022","journal-title":"Expert Rev Med Devices"},{"issue":"06","key":"ref5","doi-asserted-by":"publisher","first-page":"397","DOI":"10.5435\/00124635-200906000-00008","article-title":"Treatment of carpal tunnel syndrome","volume":"17","author":"MW Keith","year":"2009","journal-title":"J Am AcadOrthopSurg"},{"issue":"07","key":"ref6","doi-asserted-by":"publisher","first-page":"1005","DOI":"10.1016\/j.apmr.2010.03.023","article-title":"Carpal tunnel syndrome. Part II: effectiveness of surgical treatments\u2013a systematic review","volume":"91","author":"BM Huisstede","year":"2010","journal-title":"Arch Phys Med Rehabil"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD003905.pub3","article-title":"Surgical treatment options for carpal tunnel syndrome","author":"RJ Scholten","year":"2007","journal-title":"Cochrane Database Syst Rev"},{"issue":"12","key":"ref8","doi-asserted-by":"publisher","first-page":"e0143683","DOI":"10.1371\/journal.pone.0143683","article-title":"Endoscopic and open release similarly safe for the treatment of carpal tunnel syndrome. a systematic review and meta-analysis","volume":"10","author":"HS Vasiliadis","year":"2015","journal-title":"PLoS ONE"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"1399","DOI":"10.1001\/jama.2015.12208","article-title":"Extended follow-up of a randomized clinical trial of open vs endoscopic release surgery for carpal tunnel syndrome","volume":"314","author":"I Atroshi","year":"2015","journal-title":"JAMA"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"1265","DOI":"10.2106\/00004623-199309000-00002","article-title":"Carpal tunnel release: a prospective, randomized assessment of open and endoscopic methods","volume":"75","author":"RA Brown","year":"1993","journal-title":"J B o n e Joint Surg Am"},{"issue":"04","key":"ref11","doi-asserted-by":"publisher","first-page":"568","DOI":"10.1007\/s00270-016-1545-5","article-title":"Percutaneous ultrasound-guided carpal tunnel release: study upon clinical efficacy and safety","volume":"40","author":"D Petrover","year":"2017","journal-title":"CardiovascInterventRadiol"},{"issue":"04","key":"ref12","doi-asserted-by":"publisher","first-page":"248","DOI":"10.1055\/s-0038-1673360","article-title":"Ultrasound-guided surgery for carpal tunnel syndrome: a new interventional procedure","volume":"35","author":"D Petrover","year":"2018","journal-title":"SeminInterventRadiol"},{"issue":"11","key":"ref13","doi-asserted-by":"publisher","first-page":"2699","DOI":"10.1002\/jum.14618","article-title":"Minimally invasive ultrasound-guided carpal tunnel release: preliminary clinical results","volume":"37","author":"PT Henning","year":"2018","journal-title":"J Ultrasound Med"},{"issue":"06","key":"ref14","doi-asserted-by":"publisher","first-page":"1149","DOI":"10.7863\/ultra.15.07001","article-title":"Ultra-minimally invasive ultrasound guided carpal tunnel release: a randomized clinical trial","volume":"35","author":"JM Rojo-Manaute","year":"2016","journal-title":"J Ultrasound Med"},{"issue":"01","key":"ref15","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1186\/s13018-018-0771-8","article-title":"Ultrasound-guided needle release of the transverse carpal ligament with and without corticosteroid injection for the treatment of carpal tunnel syndrome","volume":"13","author":"XY Guo","year":"2018","journal-title":"J OrthopSurg Res"},{"issue":"06","key":"ref16","doi-asserted-by":"publisher","first-page":"976","DOI":"10.1007\/s00270-021-02789-2","article-title":"Ultrasound-Guided Minimal Invasive Carpal Tunnel Release: An Optimized Algorithm","volume":"44","author":"A Loizides","year":"2021","journal-title":"Cardiovasc Intervent Radiol"},{"issue":"03","key":"ref17","doi-asserted-by":"publisher","first-page":"437","DOI":"10.1016\/j.jhsa.2009.12.016","article-title":"Percutaneous carpal tunnel release compared with mini-open release using ultrasonographic guidance for both techniques","volume":"35","author":"K Nakamichi","year":"2010","journal-title":"J Hand Surg Am"},{"issue":"94","key":"ref18","doi-asserted-by":"publisher","first-page":"e131","DOI":"10.15557\/jou.2023.0022","article-title":"Anatomical considerations of US-guided carpal tunnel release in daily clinical practice","volume":"23","author":"HR Honis","year":"2023","journal-title":"J Ultrason"},{"issue":"01","key":"ref19","doi-asserted-by":"publisher","first-page":"40","DOI":"10.1007\/s11552-014-9656-4","article-title":"A non-scalpel technique for minimally invasive surgery: percutaneously looped thread transection of the transverse carpal ligament","volume":"10","author":"D Guo","year":"2015","journal-title":"Hand (N Y)"},{"issue":"04","key":"ref20","doi-asserted-by":"publisher","first-page":"689","DOI":"10.1016\/j.jhsa.2011.12.033","article-title":"Carpal tunnel release using the MANOS CTR system: preliminary results in 52 patients","volume":"37","author":"B McCormack","year":"2012","journal-title":"J Hand Surg Am"},{"issue":"02","key":"ref21","doi-asserted-by":"publisher","first-page":"460","DOI":"10.2214\/AJR.20.24383","article-title":"Minimally Invasive Ultrasound-Guided Carpal Tunnel Release Improves Long-Term Clinical Outcomes in Carpal Tunnel Syndrome","volume":"217","author":"SI Kamel","year":"2021","journal-title":"AJR Am J Roentgenol"},{"issue":"11","key":"ref22","doi-asserted-by":"publisher","first-page":"2699","DOI":"10.1002\/jum.14618","article-title":"Minimally Invasive Ultrasound-Guided Carpal Tunnel Release: Preliminary Clinical Results","volume":"37","author":"PT Henning","year":"2018","journal-title":"J Ultrasound Med"},{"issue":"03","key":"ref23","doi-asserted-by":"publisher","first-page":"441","DOI":"10.1002\/jum.15120","article-title":"Clinical Results of Ultrasound-Guided Carpal Tunnel Release Performed by a Primary Care Sports Medicine Physician","volume":"39","author":"AE Joseph","year":"2020","journal-title":"J Ultrasound Med"},{"issue":"01","key":"ref24","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1177\/1558944719842199","article-title":"A Controlled Trial Evaluating the Safety and Effectiveness of Ultrasound-Guided Looped Thread Carpal Tunnel Release","volume":"16","author":"RS Burnham","year":"2021","journal-title":"Hand (N Y)"},{"issue":"07","key":"ref25","doi-asserted-by":"publisher","first-page":"1451","DOI":"10.1002\/jum.15509","article-title":"Microinvasive Carpal Tunnel Release Using a Retractable Needle-Mounted Blade","volume":"40","author":"P Hebbard","year":"2021","journal-title":"J Ultrasound Med"},{"issue":"12","key":"ref26","doi-asserted-by":"publisher","first-page":"2400","DOI":"10.1016\/j.arthro.2015.06.023","article-title":"Ultrasonographically Guided Percutaneous Carpal Tunnel Release: Early Clinical Experiences and Outcomes","volume":"31","author":"TC Chern","year":"2015","journal-title":"Arthroscopy"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"711","DOI":"10.2147\/TCRM.S206362","article-title":"Ultrasound-guided percutaneous carpal tunnel release in patients on hemodialysis: early experiences and clinical outcomes","volume":"15","author":"PH Wang","year":"2019","journal-title":"Ther Clin Risk Manag"},{"issue":"03","key":"ref28","doi-asserted-by":"publisher","first-page":"349","DOI":"10.1016\/j.jhsg.2024.02.004","article-title":"Clinical Results of Carpal Tunnel Release Using Ultrasound Guidance in Over 100 Patients at Two to Six Years","volume":"6","author":"LC Cano","year":"2024","journal-title":"J Hand Surg Glob Online"},{"issue":"03","key":"ref29","doi-asserted-by":"publisher","first-page":"242","DOI":"10.1007\/s11552-012-9429-x","article-title":"Long-term outcomes of carpal tunnel release: a critical review of the literature","volume":"7","author":"D Louie","year":"2012","journal-title":"Hand (N Y)"},{"issue":"03","key":"ref30","doi-asserted-by":"publisher","first-page":"493","DOI":"10.1016\/j.jhsa.2005.02.007","article-title":"Mini-open blind procedure versus limited open technique for carpal tunnel release: a 30-month follow-up study","volume":"30","author":"P Cellocco","year":"2005","journal-title":"J Hand Surg Am"},{"issue":"02","key":"ref31","doi-asserted-by":"publisher","first-page":"201","DOI":"10.1177\/17531934231196407","article-title":"State of the art review. Complications after carpal tunnel release","volume":"49","author":"PN Sprangers","year":"2024","journal-title":"J Hand Surg Eur Vol"}],"container-title":["Ultraschall in der Medizin - European Journal of Ultrasound"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-2678-8214.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T22:43:55Z","timestamp":1791585835000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-2678-8214"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8,7]]},"references-count":31,"journal-issue":{"issue":"05","published-online":{"date-parts":[[2026,10,9]]},"published-print":{"date-parts":[[2026,10]]}},"URL":"https:\/\/doi.org\/10.1055\/a-2678-8214","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["0172-4614","1438-8782"],"issn-type":[{"value":"0172-4614","type":"print"},{"value":"1438-8782","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2025,8,7]]},"published":{"date-parts":[[2025,8,7]]}}}