{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,28]],"date-time":"2025-11-28T10:20:55Z","timestamp":1764325255731,"version":"3.46.0"},"reference-count":66,"publisher":"Georg Thieme Verlag KG","issue":"05","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Tierarztl Prax Ausg G Grosstiere Nutztiere"],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title>\n                  <jats:p>Dieser Artikel dient der \u00dcbersicht \u00fcber die klinisch relevanten Funktionen und\n                    Stoffwechselvorg\u00e4nge von Selen im Organismus. Ein Selenmangel wird mit\n                    verschiedenen Erkrankungen in Verbindung gebracht. Dabei sind vor allem equine\n                    und bovine Neonaten und Jungtiere von einem klinisch relevanten Selenmangel\n                    betroffen. Bei einem ausgepr\u00e4gten Mangel gehen Teile der Skelett- und\/oder\n                    Herzmuskulatur zugrunde, was zu schwerwiegenden Erkrankungen und Tod des Tieres\n                    f\u00fchren kann. Das typische Krankheitsbild ist unter verschiedenen Namen bekannt\n                    und wird h\u00e4ufig unspezifisch als Rhabdomyolyse, genauer der Ursache entsprechend\n                    als selenmangelbedingte Rhabdomyolyse, ern\u00e4hrungsbedingte Myopathie oder\n                    nutritive Muskeldystrophie (NMD) und fr\u00fcher i.d.R. als Wei\u00dfmuskelkrankheit\n                    bezeichnet. Die typischen Symptome und Behandlungsm\u00f6glichkeiten werden in dieser\n                    Zusammenfassung beschrieben.<\/jats:p>\n                  <jats:p>Da Deutschland in weiten Teilen als Selenmangelgebiet gilt, kann eine einmalige\n                    Seleninjektion beim Verdacht eines Selenmangels begr\u00fcndet auf der Anamnese und\n                    klinischen Symptomen an das betroffene Kalb oder Fohlen erfolgen, um\n                    schwerwiegende gesundheitliche Folgen durch eine NMD abzuwenden. Der Verdacht\n                    sollte \u00fcber eine Serumselenanalyse verifiziert werden, um weitere angepasste\n                    Ma\u00dfnahmen ergreifen zu k\u00f6nnen. Beim Kalb wurde mit einer herstellerkonformen\n                    Dosierung von 5,5 mg Natriumselenit und 750 mg Vitamin E\n                    (all-rac-alpha-Tocopherolacetat) keine \u00dcberversorgung an Selen erreicht.\n                    Besondere Bedeutung sollte der ad\u00e4quaten Selenversorgung des Muttertiers w\u00e4hrend\n                    der Tr\u00e4chtigkeit beigemessen werden und zeigt sich wichtiger als die\n                    Selenaufnahme \u00fcber das Kolostrum.<\/jats:p>","DOI":"10.1055\/a-2685-1049","type":"journal-article","created":{"date-parts":[[2025,10,13]],"date-time":"2025-10-13T22:49:55Z","timestamp":1760395795000},"page":"320-326","source":"Crossref","is-referenced-by-count":0,"title":["Die Bedeutung von Selen f\u00fcr neonatale Fohlen und K\u00e4lber \u2013 eine\n                    Literatur\u00fcbersicht"],"prefix":"10.1055","volume":"53","author":[{"given":"Lydia Tatjana","family":"Stahl","sequence":"additional","affiliation":[{"name":"Tierklinik f\u00fcr Reproduktionsmedizin und Neugeborenenkunde,\n                    Justus-Liebig-Universit\u00e4t Gie\u00dfen"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Axel","family":"Wehrend","sequence":"additional","affiliation":[{"name":"Tierklinik f\u00fcr Reproduktionsmedizin und Neugeborenenkunde,\n                    Justus-Liebig-Universit\u00e4t Gie\u00dfen"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2025,10,13]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"333","DOI":"10.1159\/000285956","article-title":"Zur klinischen Bedeutung von Selen: Ein systematischer Review","volume":"19","author":"R Saller","year":"2007","journal-title":"Schweiz Z Ganzheitsmed"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3390\/molecules21040545","article-title":"Selenium in Cattle: A Review","volume":"21","author":"Y Mehdi","year":"2016","journal-title":"Molecules"},{"key":"ref3","first-page":"177","volume-title":"Mineralstoffe, Vitamine und sonstige Wirkstoffe. 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