{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,9]],"date-time":"2025-12-09T23:55:16Z","timestamp":1765324516364,"version":"3.46.0"},"reference-count":18,"publisher":"Georg Thieme Verlag KG","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Z Gastroenterol"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title>\n                  <jats:p>Der EGILs (European Gastro-Intestinal Lymphoma Study)-Konsensusreport enth\u00e4lt als zentrale Therapiestrategie bei gastralen MALT-Lymphomen die H. pylori-Eradikation. Nach Erreichen einer kompletten Lymphomremission folgt eine strukturierte Nachsorge. Bei minimalen histologischen Residuen wird ein Watch-and-Wait mit regelm\u00e4\u00dfigen endoskopisch-bioptischen Kontrollen empfohlen. Dies setzt eine gute Patientencompliance voraus.<\/jats:p>\n                  <jats:p>106 Patienten (50 Frauen und 56 M\u00e4nner; Alter 59 (33\u201385) Jahre) mit gastralen MALT-Lymphomen und alleiniger H. pylori-Eradikation wurden retrospektiv analysiert. Gem\u00e4\u00df EGILs waren nach Erreichen einer kompletten Lymphomremission Nachsorgeuntersuchungen alle 6\u201312 Monate vorgesehen. Die Compliance wurde als das Verh\u00e4ltnis aus erf\u00fcllter Nachsorgepflicht zu individueller Gesamtdauer der Nachsorge berechnet und \u00fcber alle Patienten gemittelt.<\/jats:p>\n                  <jats:p>Bei 94 der 106 Patienten (89%) wurde durch die H. pylori-Eradikation eine komplette Lymphomremission oder ein stabiler Befund im Sinne minimaler histologischer Residuen erreicht. Bezogen auf den Zeitraum zwischen Prim\u00e4rdiagnose und letzter stattgefundener Nachsorge wurden 85% (Mittelwert) bzw. 95% (Median) der Nachsorgen eingehalten.<\/jats:p>\n                  <jats:p>Das Ansprechen auf die H. pylori-Eradikation und die damit verbundene Prognose waren exzellent. Die hohe Bereitschaft f\u00fcr Nachsorgeuntersuchungen nach Vollremission bzw. im Rahmen des Watch-and-Wait unterstreichen die Sicherheit der gew\u00e4hlten Therapiestrategie und des weiteren Managements dieser Patienten.<\/jats:p>","DOI":"10.1055\/a-2685-2913","type":"journal-article","created":{"date-parts":[[2025,10,7]],"date-time":"2025-10-07T22:54:34Z","timestamp":1759877674000},"page":"1246-1252","source":"Crossref","is-referenced-by-count":0,"title":["Watch-and-Wait und Nachsorge bei gastralen MALT-Lymphomen nach alleiniger Helicobacter pylori-Eradikation unter besonderer Ber\u00fccksichtigung der Patientencompliance"],"prefix":"10.1055","volume":"63","author":[{"given":"Wolfgang","family":"Fischbach","sequence":"additional","affiliation":[{"name":"Gastroenterologie Aschaffenburg, Aschaffenburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Johannes","family":"Herold","sequence":"additional","affiliation":[{"name":"Medizinische Klinik IV, Klinikum Aschaffenburg-Alzenau Standort Aschaffenburg, Aschaffenburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthias","family":"Eck","sequence":"additional","affiliation":[{"name":"Pathologisches Institut, Klinikum Aschaffenburg-Alzenau, Aschaffenburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2025,10,7]]},"reference":[{"issue":"04","key":"ref1","doi-asserted-by":"publisher","first-page":"602","DOI":"10.1055\/a1676- 5104","article-title":"Gastrale MALT-Lymphome \u2013 von pathogenetischen Erkenntnissen zu konsequenter Deeskalation der Therapie","volume":"60","author":"W Fischbach","year":"2022","journal-title":"Z Gastroenterol"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"575","DOI":"10.1016\/0140-6736(93)91409-f","article-title":"Regression of primary low-grade B-cell gastric lymphoma of mucosa-associated lymphoid tissue","volume":"342","author":"AC Wotherspoon","year":"1993","journal-title":"Lancet"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1016\/j.cgh2009.07.0171","article-title":"Effects of Helicobacter pylori Eradication on Early Stage Gastric Mucosa-Associated Lymphoid Tissue Lymphoma","volume":"8","author":"A Zullo","year":"2010","journal-title":"Clin Gastroenterol Hepatol"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1136\/gut.53.1.34","article-title":"Long term outcome of patients with gastric marginal zone B cell lymphoma of mucosa associated lymphoid tissue (MALT) following exclusive Helicobacter pylori eradication: experience from a large prospective series","volume":"53","author":"W Fischbach","year":"2004","journal-title":"GUT"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"936","DOI":"10.1200\/JCO.2005.02.3903","article-title":"Second cancers and Residual Disease in Patients Treated for Gastric Mucosa-Associated Lymphoid Tissue Lymphoma by Helicobacter pylori Eradication and Followed for 10 Years","volume":"143","author":"T W\u00fcndisch","year":"2012","journal-title":"Gastroenterology"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"747","DOI":"10.1136\/gut.2010.224949","article-title":"EGILS consensus report. 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