{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T01:06:44Z","timestamp":1772759204662,"version":"3.50.1"},"reference-count":15,"publisher":"Georg Thieme Verlag KG","issue":"03","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pneumologie"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title>\n                  <jats:p>Im vorgestellten Fall einer Patientin wird eine zystische Lungenerkrankung im Rahmen eines\n      hochgradigen Verdachts auf eine pulmonale Leichtketten-Speicherkrankheit (light chain\n      deposition disease, LCDD) beschrieben. Die LCDD ist eine sehr seltene Form einer zystischen\n      Lungenerkrankung, die sich durch ausgedehnte bilaterale Zysten und Noduli kennzeichnet. Die\n      endg\u00fcltige Diagnose erfordert eine histopathologische Sicherung, was jedoch in F\u00e4llen einer\n      respiratorischen Insuffizienz nicht immer m\u00f6glich ist. Die Diagnose einer LCDD sollte in\n      Betracht gezogen werden, wenn die klinischen Befunde nicht typisch f\u00fcr andere zystische\n      Lungenerkrankungen sind, in der HRCT das Bild einer nodul\u00e4r-zystischen Amyloidose vorliegt\n      (HRCT mit Zysten und Noduli, Noduli betreffen auch die Wand der Zysten, bevorzugte Beteiligung\n      der Peripherie der Unterfelder) oder wenn monoklonale freie Leichtketten, insbesondere\n      kappa-Leichtketten, im Serum und\/oder Urin nachgewiesen werden.<\/jats:p>","DOI":"10.1055\/a-2694-6178","type":"journal-article","created":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T23:28:48Z","timestamp":1758670128000},"page":"191-194","source":"Crossref","is-referenced-by-count":0,"title":["Eine seltene Manifestation einer zystischen Lungenerkrankung bei hochgradigem Verdacht auf pulmonale Leichtketten-Speicherkrankheit (light chain deposition disease, LCDD)"],"prefix":"10.1055","volume":"80","author":[{"given":"Nina","family":"Sicker","sequence":"additional","affiliation":[{"name":"Krankenhaus St. Maria, Fachklinik Donaustauf, Klinik f\u00fcr Pneumologie, Fachklinik Donaustauf, Donaustauf, Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sabine","family":"Gaerditz","sequence":"additional","affiliation":[{"name":"Abteilung f\u00fcr Innere Medizin III, Universit\u00e4t Regensburg, Regensburg, Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Florian","family":"Geismann","sequence":"additional","affiliation":[{"name":"Lungenzentrum, Klinik M\u00fchldorf am Inn, M\u00fchldorf am Inn, Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Okka","family":"Hamer","sequence":"additional","affiliation":[{"name":"Krankenhaus St. Maria, Fachklinik Donaustauf, Institut f\u00fcr Radiologie, Fachklinik Donaustauf, Donaustauf, Deutschland"},{"name":"Institut f\u00fcr R\u00f6ntgendiagnostik, Universit\u00e4t Regensburg, Regensburg, Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christoph","family":"Lerzer","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Pneumologie und konservative Intensivmedizin, Krankenhaus Barmherzige Br\u00fcder Regensburg, Regensburg, Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arno","family":"Mohr","sequence":"additional","affiliation":[{"name":"Lungenzentrum, Klinik M\u00fchldorf am Inn, M\u00fchldorf am Inn, Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefanie","family":"Scharf","sequence":"additional","affiliation":[{"name":"Krankenhaus St. Maria, Fachklinik Donaustauf, Institut f\u00fcr Radiologie, Fachklinik Donaustauf, Donaustauf, Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maximilian","family":"Malfertheiner","sequence":"additional","affiliation":[{"name":"Krankenhaus St. Maria, Fachklinik Donaustauf, Klinik f\u00fcr Pneumologie, Fachklinik Donaustauf, Donaustauf, Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2025,9,23]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"123","DOI":"10.14740\/jh1038","article-title":"Treatment of Light Chain Deposition Disease: A Systematic Review","volume":"11","author":"A Masood","year":"2022","journal-title":"J Hematol"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"2387","DOI":"10.1111\/jcpt.13819","article-title":"Severe lung injury induced by CD38 monoclonal antibody Daratumumab and bortezomib-containing regimen in a patient with preexisting interstitial lung disease: a case report and literature review","volume":"47","author":"M Chen","year":"2022","journal-title":"J Clin Pharm Ther"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1272\/jnms.JNMS.2019_86-1","article-title":"Monoclonal Immunoglobulin Deposition Disease and Related Diseases","volume":"86","author":"G Kanzaki","year":"2019","journal-title":"J Nippon Med Sch"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"1235","DOI":"10.1016\/s0889-8588(05)70123-4","article-title":"Nonamyloidotic monoclonal immunoglobulin deposition disease. 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