{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T23:35:26Z","timestamp":1776814526924,"version":"3.51.2"},"reference-count":30,"publisher":"Georg Thieme Verlag KG","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Z Gastroenterol"],"abstract":"<jats:title>Zusammenfassung<\/jats:title>\n                  <jats:p>Die Gastroenterologie verf\u00fcgt \u00fcber ein breit gef\u00e4chertes, evidenzbasiertes Pr\u00e4ventionsrepertoire, das weit \u00fcber die Darmkrebsvorsorge hinausgeht. Als systemrelevantes Fach tr\u00e4gt sie ma\u00dfgeblich zur Vermeidung, Fr\u00fcherkennung und Eind\u00e4mmung schwerwiegender Erkrankungen bei \u2013 von kolorektalem Karzinom \u00fcber Leberkrebs bis hin zu Speiser\u00f6hren- Leber-, Pankreas- und Magenkarzinomen. Die pr\u00e4ventiven Ma\u00dfnahmen reichen von Lebensstilinterventionen \u00fcber strukturierte Screeningprogramme und Impfstrategien bis zur gezielten Fr\u00fcherkennung bei Hochrisikogruppen. Der Erfolg gesetzlicher Programme wie des Darmkrebsscreenings oder des Hepatitisscreenings zeigt das gro\u00dfe Potenzial fr\u00fchzeitiger Interventionen. Gleichzeitig bestehen relevante L\u00fccken zwischen den evidenzbasierten Empfehlungen der DGVS Leitlinien und der Versorgungspraxis. Zudem besteht erheblicher Forschungsbedarf, etwa zur Entwicklung risikoadaptierter Strategien, innovativer diagnostischer Verfahren und zur Nutzung von Gesundheitsdaten und KI. Es bedarf einer koordinierten, sektoren\u00fcbergreifenden Pr\u00e4ventionsstrategie, um gastroenterologische Vorsorge strukturell zu verankern und weiterzuentwickeln. Die Ausrufung einer \u201eNationalen Dekade f\u00fcr Pr\u00e4vention\u201c w\u00e4re ein entscheidender Schritt \u2013 als konsequente Fortsetzung der Dekade gegen Krebs. Nur durch gemeinsames Handeln von Politik, Forschung und Versorgung l\u00e4sst sich das pr\u00e4ventive Potenzial der Gastroenterologie voll entfalten \u2013 zum Nutzen von Patient:innen und Gesundheitssystem.<\/jats:p>","DOI":"10.1055\/a-2697-3893","type":"journal-article","created":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T22:42:18Z","timestamp":1776811338000},"source":"Crossref","is-referenced-by-count":0,"title":["Pr\u00e4vention in der Gastroenterologie"],"prefix":"10.1055","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-5804-0465","authenticated-orcid":false,"given":"Petra","family":"Lynen Jansen","sequence":"additional","affiliation":[{"name":"Deutsche Gesellschaft f\u00fcr Gastroenterologie, Verdauungs- und Stoffwechselkrankheiten, Germany","place":["Berlin"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrick","family":"Michl","sequence":"additional","affiliation":[{"name":"Universit\u00e4tsKlinikum Heidelberg, BW, Germany","place":["Heidelberg"],"department":["Klinik f\u00fcr Innere Medizin 1"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"R\u00f6sch","sequence":"additional","affiliation":[{"name":"Universit\u00e4tsklinikum Hamburg-Eppendorf, HH, Germany","place":["Hamburg"],"department":["Klinik und Poliklinik f\u00fcr Interdisziplin\u00e4re Endoskopie"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Britta","family":"Siegmund","sequence":"additional","affiliation":[{"name":"Charite, CBF, Germany","place":["Berlin"],"department":["MEdicine I"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Seufferlein","sequence":"additional","affiliation":[{"name":"Universit\u00e4tsklinikum Ulm, BW, Germany","place":["Ulm"],"department":["Innere Medizin 1"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6206-0226","authenticated-orcid":false,"given":"Frank","family":"Tacke","sequence":"additional","affiliation":[{"name":"Charit\u00e9 - Universit\u00e4tsmedizin Berlin Campus Charite Mitte, BE, Germany","place":["Berlin"],"department":["Medizinischen Klinik mit Schwerpunkt Hepatologie und Gastroenterologie"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Heiner","family":"Wedemeyer","sequence":"additional","affiliation":[{"name":"Medizinische Hochschule Hannover, NDS, Germany","place":["Hannover"],"department":["Gastroenterologie, Hepatologie, Infektiologie und Endokrinologie"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2026,4,21]]},"reference":[{"key":"ref3","volume-title":"Wei\u00dfbuch Gastroenterologie 2023\/2024. Erkrankungen des Magen-Darm-Traktes, der Leber und der Bauchspeicheldr\u00fcse. Herausforderungen und Chancen f\u00fcr die Zukunft","author":"F Lammert"},{"issue":"08","key":"ref4","first-page":"423","article-title":"\u201e[Gastrointestinal tumour prevention strategies]\u201c","volume":"149","author":"M Quante","year":"2024","journal-title":"Dtsch Med Wochenschr"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1055\/a-2060-1069","article-title":"S2k-Leitlinie Gastro\u00f6sophageale Refluxkrankheit und eosinophile \u00d6sophagitis der Deutschen Gesellschaft f\u00fcr Gastroenterologie, Verdauungs- und Stoffwechselkrankheiten (DGVS)","author":"A Madisch","year":"2023","journal-title":"Z Gastroenterol"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1055\/a-2239-9802","article-title":"S3-Leitlinie Diagnostik und Therapie der Plattenepithelkarzinome und Adenokarzinome des \u00d6sophagus","volume":"62","author":"MP Ebert","year":"2024","journal-title":"Z Gastroenterol"},{"issue":"17","key":"ref7","doi-asserted-by":"publisher","first-page":"2612","DOI":"10.1053\/j.gastro.2017.04.022","article-title":"Global Prevalence of Helicobacter pylori Infection: Systematic Review and Meta-Analysis","volume":"19","author":"JKY Hooi","year":"2017","journal-title":"Gastroenterol"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"2113","DOI":"10.1136\/gutjnl-2020-320839","article-title":"Helicobacter pylori eradication therapy to prevent gastric cancer: systematic review and meta-analysis","volume":"69","author":"AC Ford","year":"2020","journal-title":"Gut"},{"key":"ref9","first-page":"544","article-title":"Aktualisierte S2k-Leitlinie Helicobacter pylori und gastroduodenale Ulkuskrankheit der Deutschen Gesellschaft f\u00fcr Gastroenterologie","volume":"61","author":"W Fischbach","year":"2023","journal-title":"Z Gastroenterol"},{"issue":"13","key":"ref11","doi-asserted-by":"publisher","first-page":"1181","DOI":"10.1056\/NEJMoa2211807","article-title":"Helicobacter pylori, Homologous-Recombination Genes, and Gastric Cancer","volume":"388","author":"Y Usui","year":"2023","journal-title":"N Engl J Med"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1080\/17410541.2025.2531737","article-title":"Gastric cancer risk and BRCA1\/2 mutations: a systematic review and meta-analysis","author":"FCA de Moraes","year":"2025","journal-title":"Personalized Medicine"},{"issue":"07","key":"ref13","doi-asserted-by":"publisher","first-page":"1002","DOI":"10.1016\/S1470-2045(21)00199-6","article-title":"Colorectal cancer incidence, mortality, and stage distribution in European countries in the colorectal cancer screening era: an international population-based study","volume":"22","author":"R Cardoso","year":"2021","journal-title":"The Lancet Oncology"},{"issue":"05","key":"ref14","doi-asserted-by":"crossref","first-page":"967","DOI":"10.14309\/ajg.0000000000001146","article-title":"Strong Reduction of Colorectal Cancer Incidence and Mortality After Screening Colonoscopy: Prospective Cohort Study From Germany","volume":"116","author":"F Guo","year":"2021","journal-title":"Am J Gastroenterol"},{"issue":"15","key":"ref16","first-page":"1373","article-title":"S3-Leitlinie Kolorektales Karzinom Version 3.1 Februar 2026","volume":"334","year":"2025","journal-title":"Z Gastroenterol"},{"key":"ref17","first-page":"769","article-title":"Aktualisierte S3-Leitlinie Colitis ulcerosa","volume":"62","author":"T Kucharzik","year":"2024","journal-title":"Z Gastroenterol"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"1229","DOI":"10.1055\/a-2309-6123","article-title":"Aktualisierte S3-Leitlinie \u201eDiagnostik und Therapie des Morbus Crohn\u201c der Deutschen Gesellschaft f\u00fcr Gastroenterologie, Verdauungs- und Stoffwechselkrankheiten (DGVS) (Version 4.1) \u2013 living guideline","volume":"62","author":"A Sturm","year":"2024","journal-title":"Z Gastroenterol"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"100","DOI":"10.1016\/j.lanepe.2022.100451","article-title":"Impact of demographic changes and screening colonoscopy on long-term projection of incident colorectal cancer cases in Germany: A modelling study","volume":"20","author":"T Heisser","year":"2022","journal-title":"The Lancet Regional Health\u2013Europe"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1055\/a-2435-5069","article-title":"Deutlicher Anstieg neu diagnostizierter Hepatitis-B- und Hepatitis-C-F\u00e4lle nach Einf\u00fchrung des Screenings in die allgemeine Gesundheitsuntersuchung (ehemals \u201eCheck-up 35\u201c) in Deutschland","author":"D H\u00fcppe","year":"2024","journal-title":"ZfG"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"1110","DOI":"10.1055\/a-1226-0241","article-title":"Prophylaxe, Diagnostik und Therapie der Hepatitis-C-Virus (HCV)-Infektion","volume":"58","author":"C Sarrazin","year":"2020","journal-title":"Z Gastroenterol"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1055\/a-1498-2512","article-title":"S3-Leitlinie Deutschen Gesellschaft f\u00fcr Gastroenterologie, Verdauungs- und Stoffwechselkrankheiten (DGVS) zur Prophylaxe, Diagnostik und Therapie der Hepatitis-B-Virusinfektion","volume":"59","author":"M Cornberg","year":"2021","journal-title":"Z Gastroenterol"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"1635","DOI":"10.1055\/a-2181-3046","article-title":"Addendum \u201eAntivirale Therapie der chronischen Hepatitis-D-Virusinfektion\u201c zur S3-Leitlinie \u201eProphylaxe, Diagnostik und Therapie der Hepatitis-B-Virusinfektion\u201c der Deutschen Gesellschaft f\u00fcr Gastroenterologie, Verdauungs- und Stoffwechselkrankheiten (DGVS)","volume":"61","author":"L Sandmann","year":"2023","journal-title":"Z Gastroenterol"},{"key":"ref25","first-page":"1346","article-title":"Aktualisierte S2k-Leitlinie nicht-alkoholische Fettlebererkrankung der Deutschen Gesellschaft f\u00fcr Gastroenterologie, Verdauungs- und Stoffwechselkrankheiten (DGVS)","volume":"60","author":"F Tacke","year":"2022","journal-title":"Z Gastroenterol"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"1077","DOI":"10.1055\/a-2309-6052","article-title":"Amendment \u201eNeue Nomenklatur zur MASLD (Metabolic Dysfunction Associated Steatotic Liver Disease; metabolische Dysfunktion-assoziierte steatotische Lebererkrankung)\u201c zur S2k-Leitlinie \u201eNicht-alkoholische Fettlebererkrankung\u201c (v.2.0\/April 2022) der Deutschen Gesellschaft f\u00fcr Gastroenterologie, Verdauungs- und Stoffwechselkrankheiten (DGVS)","volume":"62","author":"E Roeb","year":"2024","journal-title":"Z Gastroenterol"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"e159","DOI":"10.1055\/a-2460-6298","article-title":"S3-Leitlinie Diagnostik und Therapie des Hepatozellul\u00e4ren Karzinoms \u2013 Langversion","volume":"63","author":"M Bitzer","year":"2025","journal-title":"Z Gastroenterol"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1055\/a-0873-4658","article-title":"Aktualisierte S2k-Leitlinie der Deutschen Gesellschaft f\u00fcr Gastroenterologie, Verdauungs- und Stoffwechselkrankheiten (DGVS) \u201eKomplikationen der Leberzirrhose\u201c","volume":"57","author":"AL Gerbes","year":"2019","journal-title":"Z Gastroenterol"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"912","DOI":"10.1055\/a-0644-2972","article-title":"Aktualisierte S3-Leitlinie der Deutschen Gesellschaft f\u00fcr Gastroenterologie, Verdauungs- und Stoffwechselkrankheiten (DGVS) und der Deutschen Gesellschaft f\u00fcr Allgemein- und Viszeralchirurgie (DGAV) zur Pr\u00e4vention, Diagnostik und Behandlung von Gallensteinen","volume":"56","author":"C Gutt","year":"2018","journal-title":"Z Gastroenterol"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"e82","DOI":"10.1055\/a-2460-6347","article-title":"S3-Leitlinie Diagnostik und Therapie bili\u00e4rer Karzinome \u2013 Langversion","volume":"63","author":"S Gro\u00df","year":"2025","journal-title":"Z Gastroenterol"},{"issue":"07","key":"ref31","first-page":"783","article-title":"S3-Leitlinie Exokrines Pankreaskarzinom \u2013 Version 3.1","volume":"62","author":"T Seufferlein","year":"2024","journal-title":"Z Gastroenterol"},{"key":"ref32","first-page":"419","article-title":"S3-Leitlinie Pankreatitis \u2013 Leitlinie der Deutschen Gesellschaft f\u00fcr Gastroenterologie, Verdauungs- und Stoffwechselkrankheiten (DGVS)","volume":"60","author":"G Beyer","year":"2022","journal-title":"Z Gastroenterol"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1038\/s41591-023-02332-5","article-title":"A deep learning algorithm to predict risk of pancreatic cancer from disease trajectories","volume":"29","author":"D Placido","year":"2023","journal-title":"Nature Medicine"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"790","DOI":"10.1055\/a-1741-5946","article-title":"Aktualisierte S2k-Leitlinie Z\u00f6liakie der Deutschen Gesellschaft f\u00fcr Gastroenterologie, Verdauungs- und Stoffwechselkrankheiten (DGVS)","volume":"60","author":"J Felber","year":"2022","journal-title":"Z Gastroenterol"},{"issue":"15","key":"ref35","doi-asserted-by":"crossref","first-page":"1373","DOI":"10.1001\/jama.2025.10218","article-title":"Early-Onset Gastrointestinal Cancers: A Review","volume":"334","author":"T Jajakrishnan","year":"2025","journal-title":"JAMA"}],"container-title":["Zeitschrift f\u00fcr Gastroenterologie"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-2697-3893.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T22:42:23Z","timestamp":1776811343000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-2697-3893"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,21]]},"references-count":30,"URL":"https:\/\/doi.org\/10.1055\/a-2697-3893","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["0044-2771","1439-7803"],"issn-type":[{"value":"0044-2771","type":"print"},{"value":"1439-7803","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4,21]]}}}