{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T23:00:12Z","timestamp":1785279612691,"version":"3.55.0"},"reference-count":15,"publisher":"Georg Thieme Verlag KG","issue":"03","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Homeopathy"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>A well-established remedy in homeopathic practice, Spigelia anthelmia is primarily recognized for cardiovascular conditions and trigeminal neuralgia. Its role in uterine fibroid management is unknown. Uterine fibroids are common, benign uterine tumors associated with symptoms such as abnormal bleeding, pelvic pain and bladder disturbances. Conventional treatments are usually invasive, with limited long-term fertility preserving options.<\/jats:p>\n                  <jats:p>We report the case of a 63-year-old woman with type 2 diabetes who presented with post-void urinary dribbling and lower abdominal heaviness. Ultrasonography revealed a cluster of calcified fibroids (9.1\u2009\u00d7\u20096.8\u2009cm). Based on this striking and uncommon urinary modality, we prescribed the remedy Spigelia anthelmia 30cH: some symptomatic relief occurred within days, and no recurrence has been reported after full resolution of symptoms at 3.5 months. The Modified Naranjo Criteria for Homeopathy (MONARCH) score was +7.<\/jats:p>\n                  <jats:p>This case highlights a possible role for Spigelia anthelmia in fibroid-related urinary symptoms. Further studies are required to confirm the clinical significance and therapeutic potential of this observation.<\/jats:p>","DOI":"10.1055\/a-2703-3066","type":"journal-article","created":{"date-parts":[[2025,12,30]],"date-time":"2025-12-30T00:11:42Z","timestamp":1767053502000},"page":"200-203","source":"Crossref","is-referenced-by-count":0,"title":["Spigelia anthelmia for Uterine Fibroid: Case Report of a Homeopathic Cure Guided by a Urinary Modality"],"prefix":"10.1055","volume":"115","author":[{"given":"Arun R.","family":"Asuti","sequence":"additional","affiliation":[{"name":"Department of Homeopathy, Homeopathy Wing, Government Ayurveda Medical College & Hospital, Mysuru, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6150-0605","authenticated-orcid":false,"given":"Kurian","family":"Poruthukaren","sequence":"additional","affiliation":[{"name":"Department of Repertory, Yenepoya Homeopathic Medical College, AYUSH Campus, Mangalore, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2025,12,29]]},"reference":[{"key":"ref1","first-page":"231","article-title":"60-year-old male with lone paroxysmal atrial fibrillation: a homeopathic medicine case report","volume":"110","author":"T AA Hoover","year":"2017","journal-title":"Am J Homeopath Med"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1016\/S0007-0785(77)80006-9","article-title":"Facial neuralgia: an analysis of 33 cases responding to homeopathic treatment","volume":"66","author":"J HB Hoa","year":"1977","journal-title":"Br Homeopath J"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"1501","DOI":"10.1111\/1471-0528.14640","article-title":"Epidemiology of uterine fibroids: a systematic review","volume":"124","author":"E A Stewart","year":"2017","journal-title":"BJOG"},{"key":"ref4","first-page":"100","article-title":"Uterine fibroids: diagnosis and treatment","volume":"95","author":"M SD De La Cruz","year":"2017","journal-title":"Am Fam Physician"},{"key":"ref5","volume-title":"Uterine Leiomyomata","author":"K Barjon","year":"2025"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1055\/s-0037-1599090","article-title":"Recent advances in uterine fibroid etiology","volume":"35","author":"M M McWilliams","year":"2017","journal-title":"Semin Reprod Med"},{"key":"ref7","first-page":"1374821","article-title":"Selective progesterone receptor modulators for the medical treatment of uterine fibroids with a focus on ulipristal acetate","volume":"2018","author":"T Rabe","year":"2018","journal-title":"BioMed Res Int"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1016\/j.jclinepi.2017.04.026","article-title":"CARE guidelines for case reports: explanation and elaboration document","volume":"89","author":"D S Riley","year":"2017","journal-title":"J Clin 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Lamba","year":"2020","journal-title":"Homeopathy"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"1092","DOI":"10.1021\/np50121a019","article-title":"Spiganthine, the cardioactive principle of Spigelia anthelmia","volume":"58","author":"H Achenbach","year":"1995","journal-title":"J Nat Prod"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"87","DOI":"10.9734\/EJMP\/2015\/16490","article-title":"Pharmacognostic evaluation of Spigelia anthelmia Linn (Loganiaceae)","volume":"8","author":"O T Elufioye","year":"2015","journal-title":"Eur J Med Plants"}],"container-title":["Homeopathy"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-2703-3066.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T22:31:08Z","timestamp":1785277868000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-2703-3066"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,29]]},"references-count":15,"journal-issue":{"issue":"03","published-online":{"date-parts":[[2026,7,28]]},"published-print":{"date-parts":[[2026,8]]}},"URL":"https:\/\/doi.org\/10.1055\/a-2703-3066","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["1475-4916","1476-4245"],"issn-type":[{"value":"1475-4916","type":"print"},{"value":"1476-4245","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12,29]]}}}