{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T23:24:23Z","timestamp":1787095463677,"version":"build-2736575974"},"reference-count":253,"publisher":"Georg Thieme Verlag KG","issue":"04","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Semin Respir Crit Care Med"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Amyloidosis is a heterogeneous group of rare diseases characterized by the deposition of misfolded and insoluble proteins in tissues. Lung involvement, airways or parenchyma, is relatively common, but usually mild. Some patients may develop chronic progressive forms or experience life-threatening complications. In this review, we summarize the most recent advances in the comprehension of molecular mechanisms and classification of amyloidosis. We then illustrate the different forms of lung amyloidosis and the current treatment options. Increased awareness in the medical community and the creation of referral centers' networks are of paramount importance to ensure adequate management and access to treatment.<\/jats:p>","DOI":"10.1055\/a-2703-4441","type":"journal-article","created":{"date-parts":[[2025,10,14]],"date-time":"2025-10-14T23:02:14Z","timestamp":1760482934000},"page":"420-433","source":"Crossref","is-referenced-by-count":0,"title":["Pulmonary Amyloidosis"],"prefix":"10.1055","volume":"47","author":[{"given":"Stefano","family":"Levra","sequence":"additional","affiliation":[{"name":"Department of Clinical and Biological Sciences, University of Turin, Turin, Italy"},{"name":"Severe Asthma, Rare Lung Disease and Respiratory Pathophysiology Unit, San Luigi Gonzaga University Hospital, Orbassano, Turin, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcel","family":"Opitz","sequence":"additional","affiliation":[{"name":"Institute of Radiology, University Hospital Essen, Essen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Bonella","sequence":"additional","affiliation":[{"name":"Center for Interstitial and Rare Lung Diseases, Ruhrlandklinik University Hospital, University of Duisburg-Essen, Essen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2025,10,14]]},"reference":[{"issue":"06","key":"ref1","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1056\/NEJMra023144","article-title":"Molecular mechanisms of amyloidosis","volume":"349","author":"G Merlini","year":"2003","journal-title":"N Engl J Med"},{"issue":"04","key":"ref2","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1080\/13506129.2024.2405948","article-title":"Amyloid nomenclature 2024: update, novel proteins, and recommendations by the International Society of Amyloidosis (ISA) Nomenclature Committee","volume":"31","author":"J N 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