{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,14]],"date-time":"2026-04-14T23:09:12Z","timestamp":1776208152865,"version":"3.50.1"},"reference-count":19,"publisher":"Georg Thieme Verlag KG","issue":"03","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Neurol Surg A Cent Eur Neurosurg"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Collision tumors, defined as the simultaneous occurrence of two distinct neoplasms within the same anatomical location, are exceptionally rare in the clivus. The coexistence of chordoma and chronic lymphocytic leukemia (CLL) within the clivus has not been previously reported, making this case particularly noteworthy.<\/jats:p>\n                  <jats:p>We present the case of a 69-year-old woman with a known history of stable CLL who presented with a 3-month history of progressive right-sided horizontal diplopia and hemianopsia. Imaging revealed a large sellar\/suprasellar lesion with significant involvement of both cavernous sinuses, prompting surgical intervention. An endoscopic endonasal transsphenoidal and transclival approach was utilized to achieve near-total mass resection, with a small remnant left in the right cavernous sinus due to its proximity to the internal carotid artery. Histopathological examination confirmed the presence of a collision tumor composed of chordoma and CLL.<\/jats:p>\n                  <jats:p>This case represents the first reported instance of a collision tumor involving a chordoma and CLL within the clivus. The patient's postoperative course was uneventful, and she remains stable at 3-month follow-up after receiving adjuvant radiotherapy. The rarity of such a collision tumor underscores the need for heightened clinical suspicion and thorough pathological evaluation in cases presenting with atypical skull base lesions. The involvement of a multidisciplinary team was crucial in the management and favorable outcome of this complex case.<\/jats:p>","DOI":"10.1055\/a-2705-2937","type":"journal-article","created":{"date-parts":[[2025,9,19]],"date-time":"2025-09-19T23:04:39Z","timestamp":1758323079000},"page":"235-240","source":"Crossref","is-referenced-by-count":0,"title":["Collision Tumor of the Clivus: Chordoma and Chronic Lymphocytic Leukemia"],"prefix":"10.1055","volume":"87","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8850-1752","authenticated-orcid":false,"given":"Marcos Ezequiel","family":"Yasuda","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University of Buenos Aires Faculty of Medicine, Buenos Aires, Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shannon","family":"Hart","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, McMaster University Faculty of Health Sciences, Hamilton, Ontario, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jian-Qiang","family":"Lu","sequence":"additional","affiliation":[{"name":"Department of Pathology, McMaster University Faculty of Health Sciences, Hamilton, Ontario, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Almunder","family":"Algird","sequence":"additional","affiliation":[{"name":"Division of Neurosurgery, Department of Surgery, McMaster University, Hamilton General Hospital, Hamilton, Ontario, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2025,12,12]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.wneu.2018.08.065","article-title":"Primary central nervous system extranodal natural killer\/T-cell lymphoma, nasal type colliding with meningioma","volume":"120","author":"J Yan","year":"2018","journal-title":"World 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review of operative margins and surgical approaches","volume":"165","author":"N J Brown","year":"2023","journal-title":"J Neurooncol"},{"issue":"21","key":"ref16","first-page":"CASE21434","article-title":"Management of pediatric clival chordoma with extension to the craniocervical junction and occipito-cervical fusion: illustrative case","volume":"2","author":"M A Liu","year":"2021","journal-title":"J Neurosurg Case Lessons"},{"issue":"06","key":"ref17","doi-asserted-by":"crossref","first-page":"892","DOI":"10.1002\/hed.23415","article-title":"Clival chordomas: a pathological, surgical, and radiotherapeutic review","volume":"36","author":"J C Fernandez-Miranda","year":"2014","journal-title":"Head Neck"},{"issue":"06","key":"ref18","first-page":"585","article-title":"[Intracranial collision tumor\u2013a case report (author's transl)]","volume":"4","author":"T Fukaya","year":"1976","journal-title":"No Shinkei 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