{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,28]],"date-time":"2025-11-28T23:55:05Z","timestamp":1764374105412,"version":"3.46.0"},"reference-count":63,"publisher":"Georg Thieme Verlag KG","issue":"06","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Tierarztl Prax Ausg K Kleintiere Heimtiere"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title>\n                  <jats:p>Der idiopathische Chylothorax ist eine seltene Erkrankung beim Kleintier mit\n                    weitgehend unklarer \u00c4tiologie. Beim Hund konnten mittlerweile in mehreren\n                    Studien hohe Erfolgsraten nach chirurgischer Behandlung erzielt werden, die\n                    Prognose bei der Katze bleibt dagegen weiterhin ung\u00fcnstig. Ziel dieses Artikels\n                    ist es, ein integratives Verst\u00e4ndnis der Erkrankung zu entwickeln, das\n                    anatomische, pathophysiologische, physikalische und klinische Aspekte\n                    systematisch verkn\u00fcpft. Die verf\u00fcgbaren konservativen und chirurgischen\n                    Verfahren werden im Hinblick auf Erfolgsraten, Komplikationen und prognostische\n                    Relevanz eingeordnet. Dabei wird herausgearbeitet, welche therapeutischen\n                    Entscheidungen sich trotz begrenzter Datenlage in der Praxis begr\u00fcnden lassen \u2013\n                    und welche Annahmen kritisch zu hinterfragen sind. So erscheint insbesondere ein\n                    verz\u00f6gerter Operationszeitpunkt als potenziell nachteiliger Aspekt im\n                    derzeitigen Behandlungskonzept. Auch die bislang standardisierte Wahl einer weit\n                    kaudalen Ligatur des Ductus thoracicus wird im Licht\n                    anatomisch-pathophysiologischer Kenntnisse diskutiert. Die derzeitige\n                    Studienlage erlaubt zudem keine klare Indikationsstellung f\u00fcr eine Ablation der\n                    Cisterna chyli; auch zur Rolle der Perikardektomie bestehen in der neueren\n                    Literatur unterschiedliche Einsch\u00e4tzungen. Aus den dargestellten Beobachtungen\n                    ergeben sich konkrete Impulse f\u00fcr weiterf\u00fchrende Forschung und eine\n                    differenziertere klinische Entscheidungsfindung.<\/jats:p>","DOI":"10.1055\/a-2712-9192","type":"journal-article","created":{"date-parts":[[2025,11,28]],"date-time":"2025-11-28T23:50:07Z","timestamp":1764373807000},"page":"350-361","source":"Crossref","is-referenced-by-count":0,"title":["Idiopathischer Chylothorax bei Hund und Katze"],"prefix":"10.1055","volume":"53","author":[{"given":"Lukas","family":"Wie\u00dfnet","sequence":"additional","affiliation":[{"name":"Kleintierspezialisten Berlin-Brandenburg Dres. Schmerbach und H\u00f6pfner\n                    GmbH, Berlin"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Clara","family":"Girrbach","sequence":"additional","affiliation":[{"name":"Kleintierspezialisten Berlin-Brandenburg Dres. Schmerbach und H\u00f6pfner\n                    GmbH, Berlin"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kay","family":"Schmerbach","sequence":"additional","affiliation":[{"name":"Kleintierspezialisten Berlin-Brandenburg Dres. Schmerbach und H\u00f6pfner\n                    GmbH, Berlin"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2025,11,28]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"1315","DOI":"10.2460\/javma.1986.188.11.1315","article-title":"Chylothorax in 34 dogs","volume":"188","author":"T W Fossum","year":"1986","journal-title":"J Am Vet Med Assoc"},{"key":"ref2","first-page":"1060","volume-title":"(Hrsg.), Chirurgie der Kleintiere. 5. Aufl","author":"T W Fossum","year":"2021"},{"key":"ref3","first-page":"507","volume-title":"Anatomie der Hauss\u00e4ugetiere. 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results in\n                    eight dogs","volume":"34","author":"K Hayashi","year":"2005","journal-title":"Vet Surg"},{"key":"ref45","doi-asserted-by":"publisher","first-page":"976","DOI":"10.2460\/javma.252.8.976","article-title":"Comparison of thoracic duct ligation plus subphrenic pericardiectomy with or\n                    without cisterna chyli ablation for treatment of idiopathic chylothorax in\n                    cats","volume":"252","author":"S L Stockdale","year":"2018","journal-title":"J Am Vet Med Assoc"},{"key":"ref46","doi-asserted-by":"publisher","first-page":"749","DOI":"10.1016\/j.jfma.2013.10.016.","article-title":"Chemical pleurodesis for spontaneous pneumothorax","volume":"112","author":"C H How","year":"2013","journal-title":"J Formos Med Assoc"},{"key":"ref47","doi-asserted-by":"publisher","first-page":"312","DOI":"10.5326\/0460312","article-title":"Chylothorax treated via thoracic duct ligation and omentalization","volume":"46","author":"T A 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evaluation of lymphatic embolization as part of the treatment in\n                    dogs with presumptive idiopathic chylothorax","volume":"51","author":"J Carvajal","year":"2022","journal-title":"Vet Surg"},{"key":"ref52","doi-asserted-by":"publisher","first-page":"529","DOI":"10.1892\/0891-6640(1999)013<0529:tppid>2.3.co;2.","article-title":"Thoracoscopic partial pericardiectomy in 13 dogs","volume":"13","author":"J Jackson","year":"1999","journal-title":"J Vet Intern Med"},{"key":"ref53","doi-asserted-by":"publisher","first-page":"256878","DOI":"10.1155\/2012\/256878","article-title":"Tube thoracostomy: complications and its management","author":"E B Kesieme","year":"2012","journal-title":"Pulm Med"},{"key":"ref54","doi-asserted-by":"publisher","first-page":"715","DOI":"10.1111\/j.1748-5827.2006.00080.x","article-title":"Factors influencing the short-term outcome following thoracic surgery in 98\n                    dogs","volume":"47","author":"J A 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D'Agostino","year":"2025"},{"key":"ref58","doi-asserted-by":"publisher","first-page":"264","DOI":"10.1152\/jappl.1955.8.3.264","article-title":"Physical dynamics of the cough mechanism","volume":"8","author":"B B Ross","year":"1955","journal-title":"J Appl Physiol"},{"key":"ref59","first-page":"162","article-title":"\u201cCoughing chylothorax\u201d: traumatic noniatrogenic thoracic duct leak","volume":"A78","author":"BP E Mohanakrishnan","year":"2022","journal-title":"J Thorac Cardiovasc Surg"},{"key":"ref60","doi-asserted-by":"publisher","first-page":"416","DOI":"10.1186\/s12887-023-04221-9","article-title":"Cough-induced chylothorax in a two-year-old boy - case report and review of the\n                    literature","volume":"23","author":"M Anger","year":"2023","journal-title":"BMC Pediatr"},{"key":"ref61","doi-asserted-by":"publisher","first-page":"1015","DOI":"10.1111\/ahe.12745","article-title":"Anatomical variations of the thoracic duct in the dog","volume":"50","author":"K 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                   preliminary clinical study in two dogs","volume":"4","author":"A K Price","year":"2024","journal-title":"Front Vet Sci"},{"key":"ref65","doi-asserted-by":"publisher","first-page":"267","DOI":"10.1111\/vsu.12740","article-title":"Use of direct near-infrared fluorescent lymphography for thoracoscopic thoracic\n                    duct identification in 15 dogs with chylothorax","volume":"47","author":"M A Steffey","year":"2018","journal-title":"Vet Surg"}],"container-title":["Tier\u00e4rztliche Praxis Ausgabe K: Kleintiere \/ 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