{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T07:17:58Z","timestamp":1780730278030,"version":"3.54.1"},"reference-count":20,"publisher":"Georg Thieme Verlag KG","issue":"05","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Endoscopy"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Open Zenker\u2019s peroral endoscopic myotomy (OZ-POEM) was developed to overcome clinical failures arising from a persistent mucosal flap and difficult closure in Z-POEM. This study compared the outcomes of OZ-POEM and Z-POEM.<\/jats:p>\n                  <jats:p>This retrospective study included consecutive patients who underwent Z-POEM (2\/2020\u201312\/2022) and OZ-POEM (1\/2023\u201311\/2024). The primary outcome was clinical success; secondary outcomes were technical success, adverse events, procedure time, and closure cost.<\/jats:p>\n                  <jats:p>78 patients were included, 39 per group, with similar baseline characteristics. Clinical success was achieved in 94.9% and 97.4% of patients in the Z-POEM and OZ-POEM groups, respectively. Technical success was 100% in both groups. No clips (US$0) were used with OZ-POEM, whereas a median of 6 clips were used for Z-POEM (P &lt; 0.001), with a median cost of US$580 (interquartile range 485\u2013758.75) (P &lt; 0.001). Median procedure time was shorter in the OZ-POEM group (21 vs. 27 minutes; P &lt; 0.001). One patient in each group suffered a severe adverse event that required repeat endoscopic intervention.<\/jats:p>\n                  <jats:p>OZ-POEM demonstrated comparable clinical, technical, and safety outcomes to Z-POEM, but with significantly shorter procedure duration and lower closure cost. OZ-POEM is a simplified Z-POEM technique, making it more scalable for trainees and therapeutic endoscopists.<\/jats:p>","DOI":"10.1055\/a-2750-8833","type":"journal-article","created":{"date-parts":[[2025,11,19]],"date-time":"2025-11-19T00:01:56Z","timestamp":1763510516000},"page":"513-519","source":"Crossref","is-referenced-by-count":1,"title":["Open Zenker\u2019s peroral endoscopic myotomy: a comparative analysis of this modified technique versus the standard Zenker\u2019s peroral endoscopic myotomy approach"],"prefix":"10.1055","volume":"58","author":[{"given":"Harjot K.","family":"Bedi","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology, Johns Hopkins Medicine, Baltimore, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Farimah","family":"Fayyaz","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology, Johns Hopkins Medicine, Baltimore, United 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