{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,22]],"date-time":"2026-04-22T22:47:23Z","timestamp":1776898043315,"version":"3.51.2"},"reference-count":44,"publisher":"Georg Thieme Verlag KG","issue":"04","license":[{"start":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T00:00:00Z","timestamp":1770768000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Z Gastroenterol"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title>\n                  <jats:p>Das p\u00e4diatrische Kurzdarmsyndrom (KDS) mit chronischem Darmversagen (CDV) ist eine seltene, komplexe und potenziell lebensbedrohliche Erkrankung. Die Hauptursachen im Kindesalter sind nekrotisierende Enterokolitis, Volvulus, angeborene Fehlbildungen und andere Enteropathien. Die resultierende verminderte intestinale Absorptionskapazit\u00e4t macht in vielen F\u00e4llen eine parenterale Ern\u00e4hrung (PE) erforderlich. Diese ist jedoch mit Komplikationen wie Katheter-Infektionen, Leber-Erkrankungen und Thrombosen sowie mit erheblichen Einschr\u00e4nkungen der Lebensqualit\u00e4t verbunden. Ziel der multiprofessionellen Behandlung ist es deshalb, eine enterale Autonomie anzustreben, Komplikationen zu vermeiden und die Lebensqualit\u00e4t zu verbessern. Seit der Einf\u00fchrung von Teduglutid, einem GLP-2-Analogon (GLP-2: Glucagon-like peptide-2), steht eine zus\u00e4tzliche Therapie-Option zur Verf\u00fcgung, die die Fl\u00fcssigkeits- und N\u00e4hrstoff-Aufnahme verbessern und eine Reduktion des parenteralen Unterst\u00fctzungsbedarfs \u2013 bis hin zur partiellen oder vollst\u00e4ndigen Entw\u00f6hnung \u2013 erm\u00f6glichen kann. Dieses Positionspapier fasst die bisherige Evidenz zur Wirksamkeit und Sicherheit von Teduglutid bei Kindern zusammen und gibt praxisorientierte Empfehlungen der Expert*innengruppe zu folgenden Aspekten: Definition relevanter Behandlungsziele (z.B. infusionsfreie Tage, enterale Autonomie), Kriterien f\u00fcr die Indikationsstellung, Einordnung in den Behandlungsalgorithmus, Anforderungen an Aufkl\u00e4rung, Betreuung, Monitoring und Verlaufskontrollen. Damit soll ein strukturierter Handlungsrahmen f\u00fcr den klinischen Einsatz von Teduglutid im Kindes- und Jugendalter geschaffen werden.<\/jats:p>","DOI":"10.1055\/a-2757-3525","type":"journal-article","created":{"date-parts":[[2026,2,12]],"date-time":"2026-02-12T00:22:06Z","timestamp":1770855726000},"page":"372-385","source":"Crossref","is-referenced-by-count":0,"title":["Anwendung von Teduglutid bei Kurzdarmsyndrom im S\u00e4uglings-, Kindes- und Jugendalter: Positionspapier der Arbeitsgruppe \u201eChronisches Darmversagen\u201c der Gesellschaft f\u00fcr P\u00e4diatrische Gastroenterologie und Ern\u00e4hrung (GPGE)"],"prefix":"10.1055","volume":"64","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9487-8812","authenticated-orcid":false,"given":"Carsten","family":"Posovszky","sequence":"additional","affiliation":[{"name":"Gastroenterologie und Ern\u00e4hrung, Universit\u00e4ts-Kinderspital Z\u00fcrich, Z\u00fcrich, Switzerland"},{"name":"Klinik f\u00fcr Kinder- und Jugendmedizin, University Ulm Medical Centre, Ulm, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jan","family":"de Laffolie","sequence":"additional","affiliation":[{"name":"Paediatrics, Justus Liebig Universitat Giessen Fachbereich Medizin, Giessen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephan","family":"Henning","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr P\u00e4diatrie mit Schwerpunkt Gastroenterologie, Nephrologie und Stoffwechselmedizin, Charite-Universit\u00e4tsmedizin Berlin, Campus Virchow Klinikum, Berlin, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antje","family":"Ballauf","sequence":"additional","affiliation":[{"name":"Zentrum f\u00fcr Kinder- und Jugendmedizin, HELIOS Klinikum Krefeld, Krefeld, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jens","family":"Berrang","sequence":"additional","affiliation":[{"name":"Westf\u00e4lisches Kinderzentrum, Abteilung f\u00fcr Kindergastroenterologie, Klinikum Dortmund gGmbH, Dortmund, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Victor","family":"Bildheim","sequence":"additional","affiliation":[{"name":"St. Josef-Hospital Bochum, Universit\u00e4tsklinik f\u00fcr Kinder- und Jugendmedizin, Abteilung f\u00fcr P\u00e4diatrische Gastroenterologie, Ruhr-Universit\u00e4t Bochum, Bochum, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gunter","family":"Burmester","sequence":"additional","affiliation":[{"name":"Gastroenterologie, AKK Altonaer Kinderkrankenhaus gGmbH, Hamburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andreas","family":"Entenmann","sequence":"additional","affiliation":[{"name":"Universit\u00e4tsklinikum Innsbruck, Department f\u00fcr P\u00e4diatrie I, Universit\u00e4t Innsbruck, Innsbruck, Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gunter Matthias Christian","family":"Flemming","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Kinder- und Jugendmedizin, Universit\u00e4tsklinikum Leipzig, Leipzig, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Judith","family":"Garino","sequence":"additional","affiliation":[{"name":"Garino Medical Consulting, Nidda, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sebastian","family":"Gillmeister","sequence":"additional","affiliation":[{"name":"Universit\u00e4tsklinikum Ulm Klinik f\u00fcr Kinder- und Jugendmedizin, Ulm, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kathrin","family":"Krohn","sequence":"additional","affiliation":[{"name":"Integriertes Sozialp\u00e4diatrisches Zentrum im Dr. von Haunerschen Kinderspital, Ludwig-Maximilians-Universit\u00e4t M\u00fcnchen, M\u00fcnchen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Corinne","family":"Legeret","sequence":"additional","affiliation":[{"name":"P\u00e4diatrische Gastroenterologie, Hepatologie & Ern\u00e4hrung, Universit\u00e4ts-Kinderspital beider Basel, Basel, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eberhard","family":"Lurz","sequence":"additional","affiliation":[{"name":"P\u00e4diatrische Gastroenterologie und Hepatologie, Universit\u00e4tsklinikum M\u00fcnchen, Dr. von Haunersches Kinderspital, M\u00fcnchen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steffen","family":"Reinsch","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Kinder- und Jugendmedizin, P\u00e4diatrische Gastroenterologie, Hepatologie und Endoskopie, Universit\u00e4tsklinikum Jena, Jena, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Franziska","family":"Righini-Grunder","sequence":"additional","affiliation":[{"name":"Abteilung f\u00fcr Gastroenterologie, Hepatologie und Ern\u00e4hrung, Kinderspital Zentralschweitz, Luzern, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aline","family":"R\u00fcckel","sequence":"additional","affiliation":[{"name":"P\u00e4diatrische Gastroenterologie, Universit\u00e4tsklinikum Erlangen Kinder- und Jugendklinik, Erlangen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martina","family":"Kohl-Sobania","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Kinder- und Jugendmedizin, Universit\u00e4tsklinikum Schleswig-Holstein, Kiel, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Johannes","family":"Hilberath","sequence":"additional","affiliation":[{"name":"Abteilung Kinderheilkunde I, P\u00e4diatrische Gastroenterologie und Hepatologie, Universit\u00e4tsklinikum T\u00fcbingen Klinik f\u00fcr Kinder- und Jugendmedizin, T\u00fcbingen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2026,2,11]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"723","DOI":"10.1016\/j.jpeds.2012.03.062","article-title":"Natural history of pediatric intestinal failure: initial report from the Pediatric Intestinal Failure Consortium","volume":"161","author":"RH Squires","year":"2012","journal-title":"The Journal of pediatrics"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"e57","DOI":"10.1055\/s-0034-1369922","article-title":"S3-Leitlinie der Deutschen Gesellschaft f\u00fcr Ern\u00e4hrungsmedizin e.\u200aV. in Zusammenarbeit mit der AKE, der GESKES und der DGVS","volume":"39","author":"G Lamprecht","year":"2014","journal-title":"Aktuelle Ern\u00e4hrungsmedizin"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"281","DOI":"10.1097\/MPG.0000000000003849","article-title":"Nutrition and Intestinal Rehabilitation of Children With Short Bowel Syndrome: A Position Paper of the ESPGHAN Committee on Nutrition. Part 1: From Intestinal Resection to Home Discharge","volume":"77","author":"L Norsa","year":"2023","journal-title":"Journal of pediatric gastroenterology and nutrition"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"3521","DOI":"10.1007\/s10620-020-06140-6","article-title":"Teduglutide Promotes Epithelial Tight Junction Pore Function in Murine Short Bowel Syndrome to Alleviate Intestinal Insufficiency","volume":"65","author":"J Reiner","year":"2020","journal-title":"Digestive diseases and sciences"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"561","DOI":"10.1146\/annurev-physiol-021113-170317","article-title":"Physiology and pharmacology of the enteroendocrine hormone glucagon-like peptide-2","volume":"76","author":"DJ Drucker","year":"2014","journal-title":"Annual review of physiology"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"602","DOI":"10.1097\/MCG.0b013e3182828f57","article-title":"Teduglutide enhances structural adaptation of the small intestinal mucosa in patients with short bowel syndrome","volume":"47","author":"KA Tappenden","year":"2013","journal-title":"J Clin Gastroenterol"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"237","DOI":"10.1053\/j.sempedsurg.2018.07.008","article-title":"Advances in glucagon like peptide-2 therapy. physiology, current indications and future directions","volume":"27","author":"DL Sigalet","year":"2018","journal-title":"Semin Pediatr Surg"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"1224","DOI":"10.1136\/gut.2004.061440","article-title":"Teduglutide (ALX-0600), a dipeptidyl peptidase IV resistant glucagon-like peptide 2 analogue, improves intestinal function in short bowel syndrome patients","volume":"54","author":"PB Jeppesen","year":"2005","journal-title":"Gut"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"102","DOI":"10.1016\/j.jpeds.2016.10.027","article-title":"Outcomes from a 12-Week, Open-Label, Multicenter Clinical Trial of Teduglutide in Pediatric Short Bowel Syndrome","volume":"181","author":"BA Carter","year":"2017","journal-title":"The Journal of pediatrics"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"621","DOI":"10.1002\/jpen.1690","article-title":"Safety and Efficacy of Teduglutide in Pediatric Patients With Intestinal Failure due to Short Bowel Syndrome: A 24-Week, Phase III Study","volume":"44","author":"SA Kocoshis","year":"2020","journal-title":"JPEN J Parenter Enteral Nutr"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"1456","DOI":"10.1002\/jpen.2061","article-title":"Safety Findings in Pediatric Patients During Long-Term Treatment With Teduglutide for Short-Bowel Syndrome-Associated Intestinal Failure: Pooled Analysis of 4 Clinical Studies","volume":"45","author":"S Hill","year":"2021","journal-title":"JPEN J Parenter Enteral Nutr"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"298","DOI":"10.1097\/MPG.0000000000003850","article-title":"Nutrition and Intestinal Rehabilitation of Children With Short Bowel Syndrome: A Position Paper of the ESPGHAN Committee on Nutrition. Part 2: Long-Term Follow-Up on Home Parenteral Nutrition","volume":"77","author":"L Norsa","year":"2023","journal-title":"Journal of pediatric gastroenterology and nutrition"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"902","DOI":"10.1136\/gut.2010.218271","article-title":"Randomised placebo-controlled trial of teduglutide in reducing parenteral nutrition and\/or intravenous fluid requirements in patients with short bowel syndrome","volume":"60","author":"PB Jeppesen","year":"2011","journal-title":"Gut"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"1473","DOI":"10.1053\/j.gastro.2012.09.007","article-title":"Teduglutide reduces need for parenteral support among patients with short bowel syndrome with intestinal failure","volume":"143","author":"PB Jeppesen","year":"2012","journal-title":"Gastroenterology"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"e142","DOI":"10.1038\/ctg.2015.69","article-title":"Long-Term Teduglutide for the Treatment of Patients With Intestinal Failure Associated With Short Bowel Syndrome","volume":"7","author":"LK Schwartz","year":"2016","journal-title":"Clin Transl Gastroenterol"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"666","DOI":"10.1097\/mpg.0000000000003922","article-title":"Effects of Teduglutide on Diarrhea in Pediatric Patients with Short Bowel Syndrome-Associated Intestinal Failure","volume":"77","author":"A Fifi","year":"2023","journal-title":"Journal of pediatric gastroenterology and nutrition"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"339","DOI":"10.1097\/MPG.0000000000003867","article-title":"Efficacy and Safety of Teduglutide in Infants and Children With Short Bowel Syndrome Dependent on Parenteral Support","volume":"77","author":"M Chiba","year":"2023","journal-title":"Journal of pediatric gastroenterology and nutrition"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"791","DOI":"10.1002\/jpn3.12291","article-title":"Erratum","volume":"79","author":"M Chiba","year":"2024","journal-title":"Journal of pediatric gastroenterology and nutrition"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"734","DOI":"10.1097\/MPG.0000000000002899","article-title":"Experience With Teduglutide in Pediatric Short Bowel Syndrome: First Real-life Data","volume":"71","author":"E Ramos Boluda","year":"2020","journal-title":"Journal of pediatric gastroenterology and nutrition"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"293","DOI":"10.1097\/MPG.0000000000003541","article-title":"The Variable Response to Teduglutide in Pediatric Short Bowel Syndrome: A Single Country Real-Life Experience","volume":"75","author":"A Guz-Mark","year":"2022","journal-title":"Journal of pediatric gastroenterology and nutrition"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"3173","DOI":"10.1007\/s00431-024-05577-5","article-title":"Early use of teduglutide in paediatric patients with intestinal failure is associated with a greater response rate: a multicenter study","volume":"183","author":"M German-Diaz","year":"2024","journal-title":"European journal of pediatrics"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"1152","DOI":"10.1016\/j.ajcnut.2023.02.019","article-title":"Long-term treatment with teduglutide: a 48-week open-label single-center clinical trial in children with short bowel syndrome","volume":"117","author":"C Lambe","year":"2023","journal-title":"The American journal of clinical nutrition"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.3390\/jcm13051238","article-title":"Evaluation of the Effectiveness of Teduglutide Treatment in Patients with Short Bowel Syndrome in Slovakia-Multicenter Real-World Study","volume":"13","author":"L Gombo\u0161ov\u00e1","year":"2024","journal-title":"J Clin Med"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1016\/j.eclinm.2025.103343","article-title":"Predictors of response and enteral autonomy in children with short bowel syndrome treated with teduglutide: a real-life multicentre cohort study","volume":"85","author":"L Norsa","year":"2025","journal-title":"EClinicalMedicine"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"1501","DOI":"10.1080\/14740338.2021.1940947","article-title":"The safety of available treatment options for short bowel syndrome and unmet needs","volume":"20","author":"L Pironi","year":"2021","journal-title":"Expert Opin Drug Saf"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"652","DOI":"10.1002\/jpen.1982","article-title":"De Novo Development of Distal Jejunal and Duodenal Adenomas After 41 Months of Teduglutide Treatment in a Patient With Short-Bowel Syndrome: A Case Report","volume":"45","author":"S Pevny","year":"2021","journal-title":"JPEN J Parenter Enteral Nutr"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1080\/14740338.2025.2493355","article-title":"Comprehensive analysis of adverse drug reactions associated with teduglutide: post-marketing insights and safety implications","author":"P Kudaravalli","year":"2025","journal-title":"Expert Opin Drug Saf"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"1143","DOI":"10.1016\/j.ajcnut.2023.02.015","article-title":"Unexpected upper gastrointestinal polyps in patients with short bowel syndrome treated with teduglutide: need for close monitoring","volume":"117","author":"B de Dreuille","year":"2023","journal-title":"The American journal of clinical nutrition"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"e389","DOI":"10.1097\/PG9.0000000000000389","article-title":"Gastric Foveolar Hyperplastic Polyps in 2 Children With Short Bowel Syndrome on Long-Term Teduglutide","volume":"4","author":"JA Salazar","year":"2023","journal-title":"JPGN Rep"},{"key":"ref30","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1002\/jpn3.12411","article-title":"Impact of parenteral nutrition on quality of life, the family and gastrointestinal symptoms in children with intestinal failure","volume":"80","author":"RA Thomassen","year":"2025","journal-title":"Journal of pediatric gastroenterology and nutrition"},{"key":"ref31","doi-asserted-by":"publisher","DOI":"10.3390\/children11050536","article-title":"Quality of Life of Children with Short Bowel Syndrome from Patients' and Parents' Points of View","volume":"11","author":"C Kiessling","year":"2024","journal-title":"Children (Basel)"},{"key":"ref32","doi-asserted-by":"publisher","first-page":"983","DOI":"10.1016\/j.jpedsurg.2013.02.070","article-title":"The impact of multi-disciplinary intestinal rehabilitation programs on the outcome of pediatric patients with intestinal failure: a systematic review and meta-analysis","volume":"48","author":"JD Stanger","year":"2013","journal-title":"Journal of pediatric surgery"},{"key":"ref33","doi-asserted-by":"publisher","first-page":"652","DOI":"10.1002\/jpen.2212","article-title":"Prospective evaluation of the family\u2019s health-related quality of life in pediatric intestinal failure","volume":"46","author":"VC Neam","year":"2022","journal-title":"JPEN J Parenter Enteral Nutr"},{"key":"ref34","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1016\/j.jpedsurg.2021.11.007","article-title":"Child self-reported quality of life in pediatric intestinal failure","volume":"57","author":"M Wong","year":"2022","journal-title":"Journal of pediatric surgery"},{"key":"ref35","doi-asserted-by":"publisher","DOI":"10.3389\/fnut.2022.866518","article-title":"Use of Teduglutide in Children With Intestinal Failure: A Systematic Review","volume":"9","author":"F Gigola","year":"2022","journal-title":"Front Nutr"},{"key":"ref36","doi-asserted-by":"publisher","DOI":"10.1002\/jpen.1687","article-title":"Enteral Autonomy and Days Off Parenteral Support With Teduglutide Treatment for Short Bowel Syndrome in the STEPS Trials","author":"DL Seidner","year":"2019","journal-title":"JPEN J Parenter Enteral Nutr"},{"key":"ref37","doi-asserted-by":"publisher","first-page":"697","DOI":"10.1097\/MPG.0000000000002924","article-title":"Use of GLP-2 May Herald a New Era of Improved Outcome of Short Bowel Syndrome-associated Intestinal Failure","volume":"71","author":"S Hill","year":"2020","journal-title":"Journal of pediatric gastroenterology and nutrition"},{"key":"ref38","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1016\/j.jpeds.2021.06.025","article-title":"Trends in Pediatric Intestinal Failure: A Multicenter, Multinational Study","volume":"237","author":"D Gattini","year":"2021","journal-title":"The Journal of pediatrics"},{"key":"ref39","doi-asserted-by":"publisher","first-page":"533","DOI":"10.1007\/s00383-022-05074-6","article-title":"Patient-level costing analysis of paediatric short bowel syndrome care in a specialist tertiary centre","volume":"38","author":"BC Jones","year":"2022","journal-title":"Pediatric surgery international"},{"key":"ref40","doi-asserted-by":"publisher","first-page":"1320","DOI":"10.1016\/j.dld.2022.04.028","article-title":"Teduglutide in pediatric intestinal failure: A position statement of the Italian society of pediatric gastroenterology, hepatology and nutrition (SIGENP)","volume":"54","author":"A Diamanti","year":"2022","journal-title":"Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver"},{"key":"ref41","doi-asserted-by":"publisher","first-page":"172","DOI":"10.1055\/a-2212-6874","article-title":"The Development of the International Intestinal Failure Registry and an Overview of its Results","volume":"34","author":"Y Avitzur","year":"2024","journal-title":"Eur J Pediatr Surg"},{"key":"ref42","doi-asserted-by":"publisher","DOI":"10.3238\/arztebl.m2024.0168","article-title":"The Care of Children and Adolescents With Chronic Inflammatory Bowel Disease: A Cluster-Randomized Trial on Improving the Guideline Conformity of Treatment by the Use of the CEDATA-GPGE Patient Registry","author":"L Tischler","year":"2024","journal-title":"Deutsches Arzteblatt international"},{"key":"ref43","doi-asserted-by":"publisher","first-page":"2401","DOI":"10.1016\/j.clnu.2018.06.954","article-title":"ESPGHAN\/ESPEN\/ESPR\/CSPEN guidelines on pediatric parenteral nutrition: Home parenteral nutrition","volume":"37","author":"S Hill","year":"2018","journal-title":"Clin Nutr"},{"key":"ref44","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1055\/s-0032-1332980","article-title":"Leitlinie der Deutschen Gesellschaft f\u00fcr Ern\u00e4hrungsmedizin (DGEM)","volume":"38","author":"L Valentini","year":"2013","journal-title":"Aktuelle Ern\u00e4hrungsmedizin"}],"container-title":["Zeitschrift f\u00fcr Gastroenterologie"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-2757-3525.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,22]],"date-time":"2026-04-22T22:31:41Z","timestamp":1776897101000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-2757-3525"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2,11]]},"references-count":44,"journal-issue":{"issue":"04","published-online":{"date-parts":[[2026,4,22]]},"published-print":{"date-parts":[[2026,4]]}},"URL":"https:\/\/doi.org\/10.1055\/a-2757-3525","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["0044-2771","1439-7803"],"issn-type":[{"value":"0044-2771","type":"print"},{"value":"1439-7803","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,2,11]]}}}