{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,20]],"date-time":"2026-04-20T22:47:43Z","timestamp":1776725263056,"version":"3.51.2"},"reference-count":10,"publisher":"Georg Thieme Verlag KG","issue":"04","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Klin Monbl Augenheilkd"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Purpose To describe the intraoperative diagnosis and targeted surgical management of Uveitis\u2013Glaucoma\u2013Hyphema (UGH) syndrome caused by a vertically misaligned intra-ocular lens (IOL) haptic that had escaped previous detection because of poor pharmacological mydriasis.<\/jats:p>\n                  <jats:p>Methods Clinical records, surgical notes, referral letters, and intra-operative videos were retrospectively reviewed. A literature search was performed to identify comparable cases.<\/jats:p>\n                  <jats:p>Results An 86-year-old man was referred to our clinic for IOL exchange after 10 months of recurrent anterior segment and vitreous hemorrhages, elevated intra-ocular pressure (IOP), anterior-chamber inflammation, and temporal iris transillumination\u2013findings consistent with UGH syndrome. Planned surgery included pars plana vitrectomy (PPV) and IOL exchange. Intra-operatively, pharmacologic dilation remained inadequate; however, anterior-segment exploration revealed a temporal capsular-bag defect with the corresponding haptic displaced into the ciliary sulcus, lying perpendicular to the iris, while the toric IOL optic remained well centred and the bag mechanically stable. The dislocated haptic was carefully severed and removed, with the toric IOL intentionally preserved in its original, well-centered position. PPV cleared the vitreous haemorrhage, and retinal inspection was unremarkable. Post-operatively, topical antibiotics and corticosteroids were administered, and a\n          topical carbonic anhydrase inhibitors\/\u03b2-blocker controlled transiently elevated IOP. Best-corrected visual acuity improved from 0.25 to 0.63 Snellen decimal IOP normalised, and no further haemorrhagic or inflammatory episodes occurred during follow-up.<\/jats:p>\n                  <jats:p>Conclusion In selected cases of UGH syndrome, complete IOL exchange may be unnecessary. When the optic is well centred and the capsular bag intact, removal of the offending haptic alone can abolish pathological iris\u2013IOL contact and resolve UGH manifestations.<\/jats:p>","DOI":"10.1055\/a-2761-5399","type":"journal-article","created":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T23:59:34Z","timestamp":1773791974000},"page":"399-402","source":"Crossref","is-referenced-by-count":0,"title":["Targeted Management of Uveitis-Glaucoma-Hyphema Syndrome by Selective Haptic Removal: A Case Report"],"prefix":"10.1055","volume":"243","author":[{"given":"Davide","family":"Ardizzone","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Pallas Kliniken, Olten, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6907-1112","authenticated-orcid":false,"given":"Christoph","family":"Tappeiner","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Pallas Kliniken, Olten, Switzerland"},{"name":"Medical Faculty, University of Bern, Switzerland"},{"name":"Department of Ophthalmology, University Hospital Essen, University Duisburg-Essen, Essen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tamer","family":"Tandogan","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Pallas Kliniken, Olten, Switzerland"},{"name":"Department of Ophthalmology, David J. Apple Center for Vision Research, University Hospital Heidelberg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2026,3,17]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"50","DOI":"10.1016\/s0146-2776(78)80054-8","article-title":"The uveitis-glaucoma-hyphema syndrome associated with the Mark VIII anterior chamber lens implant","volume":"4","author":"F T Ellingson","year":"1978","journal-title":"J Am Intraocul Implant Soc"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/0039-6257(84)90113-9","article-title":"Complications of intraocular lenses. A historical and histopathological review","volume":"29","author":"D J Apple","year":"1984","journal-title":"Surv Ophthalmol"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"450","DOI":"10.1016\/s0146-2776(83)80089-5","article-title":"Lens-induced complications with anterior chamber lens implants: a comparison with iris supported and posterior chamber lenses","volume":"9","author":"R C Maynor","year":"1983","journal-title":"J Am Intraocul Implant Soc"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"839","DOI":"10.1016\/s0002-9394(02)01386-7","article-title":"Ultrasound biomicroscopy in uveitis-glaucoma-hyphema syndrome","volume":"133","author":"S Piette","year":"2002","journal-title":"Am J Ophthalmol"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1111\/aos.14477","article-title":"Seventy-one cases of uveitis-glaucoma-hyphaema syndrome","volume":"99","author":"L Armonaite","year":"2021","journal-title":"Acta Ophthalmol"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"11","DOI":"10.22336\/rjo.2017.3","article-title":"Uveitis-Glaucoma-Hyphaema Syndrome. General review","volume":"61","author":"M Zemba","year":"2017","journal-title":"Rom J Ophthalmol"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"1445","DOI":"10.1016\/j.jcrs.2009.04.027","article-title":"Complications of sulcus placement of single-piece acrylic intraocular lenses: recommendations for backup IOL implantation following posterior capsule rupture","volume":"35","author":"D F Chang","year":"2009","journal-title":"J Cataract Refract Surg"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"581","DOI":"10.1055\/a-0829-6036","article-title":"Uveitis-Glaucoma-Hyphema Syndrome Treated with Haptic Amputation","volume":"236","author":"M El Wardani","year":"2019","journal-title":"Klin Monbl Augenheilkd"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"e36303","DOI":"10.7759\/cureus.36303","article-title":"Haptic Amputation Under Endoscopic Guidance in Uveitis-Glaucoma-Hyphema Syndrome: A Case Report","volume":"15","author":"M Alshehri","year":"2023","journal-title":"Cureus"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"383","DOI":"10.1159\/000538063","article-title":"Occult Uveitis-Glaucoma-Hyphema Syndrome Caused by PCIOL with Peripheral Capsular Tear","volume":"15","author":"J Dossantos","year":"2024","journal-title":"Case Rep Ophthalmol"}],"container-title":["Klinische Monatsbl\u00e4tter f\u00fcr Augenheilkunde"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-2761-5399.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,20]],"date-time":"2026-04-20T22:35:34Z","timestamp":1776724534000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-2761-5399"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,17]]},"references-count":10,"journal-issue":{"issue":"04","published-online":{"date-parts":[[2026,4,20]]},"published-print":{"date-parts":[[2026,4]]}},"URL":"https:\/\/doi.org\/10.1055\/a-2761-5399","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["0023-2165","1439-3999"],"issn-type":[{"value":"0023-2165","type":"print"},{"value":"1439-3999","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,17]]}}}