{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,24]],"date-time":"2026-01-24T03:18:38Z","timestamp":1769224718329,"version":"3.49.0"},"reference-count":5,"publisher":"Georg Thieme Verlag KG","issue":"01","license":[{"start":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T00:00:00Z","timestamp":1768348800000},"content-version":"vor","delay-in-days":13,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["AJP Rep"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Poikiloderma with neutropenia is an autosomal recessive condition characterized by postinflammatory poikiloderma and chronic neutropenia. To date, there is no published literature reporting on the impact of pregnancy on this rare genetic disorder.<\/jats:p>\n                  <jats:p>This case highlights a successful pregnancy outcome in a 26-year-old gravida 1 para 0 female with poikiloderma with neutropenia. Her pregnancy was complicated by thrombocytopenia, low fetal fraction, and high-risk cell-free DNA result.<\/jats:p>\n                  <jats:p>The findings of low fetal fraction and high-risk aneuploidy were unexpected given normal neonatal outcome. It is not yet well understood whether these findings are related to the genetic condition itself or use of medications used to manage her condition.<\/jats:p>","DOI":"10.1055\/a-2764-3829","type":"journal-article","created":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T00:31:54Z","timestamp":1768437114000},"page":"e27-e29","source":"Crossref","is-referenced-by-count":0,"title":["Pregnancy and Poikiloderma with Neutropenia"],"prefix":"10.1055","volume":"16","author":[{"given":"Jessica","family":"Nelson","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, University of Toledo and Toledo ProMedica Hospital, Toledo, Ohio, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hailey","family":"Cox","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, University of Toledo and Toledo ProMedica Hospital, Toledo, Ohio, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ira","family":"Hamilton","sequence":"additional","affiliation":[{"name":"Department of Maternal-Fetal Medicine, Toledo ProMedica Hospital, Toledo, Ohio, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nauman","family":"Khurshid","sequence":"additional","affiliation":[{"name":"Department of Maternal-Fetal Medicine, Toledo ProMedica Hospital, Toledo, Ohio, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nikolina","family":"Docheva","sequence":"additional","affiliation":[{"name":"Department of Maternal-Fetal Medicine, Toledo ProMedica Hospital, Toledo, Ohio, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2026,1,22]]},"reference":[{"issue":"01","key":"ref1","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1186\/s13256-025-05027-2","article-title":"Poikiloderma with neutropenia: a case report","volume":"19","author":"J Chekr","year":"2025","journal-title":"J Med Case Rep"},{"issue":"01","key":"ref2","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1038\/s41467-017-00484-w","article-title":"Usb1 controls U6 snRNP assembly through evolutionarily divergent cyclic phosphodiesterase activities","volume":"8","author":"A L Didychuk","year":"2017","journal-title":"Nat Commun"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"680363","DOI":"10.3389\/fmed.2021.680363","article-title":"Poikiloderma with neutropenia and mastocytosis: a case report and a review of dermatological signs","volume":"8","author":"V Piccolo","year":"2021","journal-title":"Front Med (Lausanne)"},{"issue":"06","key":"ref4","doi-asserted-by":"crossref","first-page":"1214","DOI":"10.3390\/cancers13061214","article-title":"Maternal and neonatal outcome after the use of G-CSF for cancer treatment during pregnancy","volume":"13","author":"C Berends","year":"2021","journal-title":"Cancers (Basel)"},{"issue":"06","key":"ref6","doi-asserted-by":"crossref","first-page":"100466","DOI":"10.1016\/j.ajogmf.2021.100466","article-title":"The impact of maternal autoimmune disease on cell-free DNA test characteristics","volume":"3","author":"H J MacKinnon","year":"2021","journal-title":"Am J Obstet Gynecol MFM"}],"container-title":["American Journal of Perinatology Reports"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-2764-3829.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T01:13:17Z","timestamp":1769130797000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-2764-3829"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":5,"journal-issue":{"issue":"01","published-online":{"date-parts":[[2026,1,14]]},"published-print":{"date-parts":[[2026,1]]}},"URL":"https:\/\/doi.org\/10.1055\/a-2764-3829","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["2157-6998","2157-7005"],"issn-type":[{"value":"2157-6998","type":"print"},{"value":"2157-7005","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2026,1,14]]},"published":{"date-parts":[[2026,1]]}}}