{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T23:58:23Z","timestamp":1781135903814,"version":"3.54.1"},"reference-count":15,"publisher":"Georg Thieme Verlag KG","issue":"03","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Z Geburtshilfe Neonatol"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>This study aims to compare cerebral and splanchnic regional oxygen\n                        saturation(rSO2) in premature infants with duct-dependent congenital heart\n                        disease (CHD) using near-infrared spectroscopy (NIRS) with that of\n                        case-control premature infants without CHD.<\/jats:p>\n                  <jats:p>Premature infants with duct-dependent CHD\n                            requiring prostaglandin E1 (PGE1) for more than 10 days and control\n                            preterm infants (without CHD) were monitored for 36 hours using NIRS to\n                            assess cerebral and splanchnic rSO2. Both groups received gavage enteral\n                            feeding. Multiple measurements were taken around feeding at three\n                            different times (30 minutes before, during, and 30 minutes after\n                            feeding).<\/jats:p>\n                  <jats:p>A total of 16 cases were included in the study (8 CHD and 8 controls). The\n                        CHD infants had the following diagnoses: four with aortic coarctation, two\n                        with interrupted aortic arch, one with hypoplastic left heart syndrome, and\n                        one with D-transposition of the great arteries. The median gestational age\n                        (35 weeks in duct-dependent CHD vs. 34 weeks in controls) and birth weight\n                        (1850 g vs. 1800 g, respectively) were similar between the two groups\n                        (p&gt;0.05). The median cerebral NIRS measurements in the controls were 12\n                        points higher than in the cases (P=0.03), and the splanchnic NIRS\n                        measurements were 20 points higher (P=0.01). The median cerebral NIRS\n                        measurements in the cases were 60%, 64%, and 62% at baseline, during\n                        feeding, and post-feeding, respectively, while the controls had values of\n                        72%, 74%, and 71% at the same times. The median splanchnic NIRS measurements\n                        in the cases were 30%, 35%, and 38% at baseline, during feeding, and\n                        post-feeding, respectively, while the controls had values of 50%, 52%, and\n                        54%. Similar changes in cerebral and splanchnic NIRS values were observed\n                        during feeding in both the cases and controls (p&gt;0.05).<\/jats:p>\n                  <jats:p>Premature neonates with duct-dependent CHD have a reduction in both cerebral\n                        and splanchnic rSO2 values when compared to age-matched controls. NIRS\n                        monitoring demonstrated lower regional oxygen saturation levels in\n                        duct-dependent CHD infants compared with controls, suggesting reduced tissue\n                        oxygenation during feeding. Further studies with larger sample sizes are\n                        needed in this area.<\/jats:p>","DOI":"10.1055\/a-2764-6472","type":"journal-article","created":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T23:50:01Z","timestamp":1768002601000},"page":"228-231","source":"Crossref","is-referenced-by-count":0,"title":["Changes in Cerebral and Splanchnic Tissue Oxygenation During Enteral\n                    Feeding in Premature Infants with Duct-Dependent Congenital Heart\n                    Disease"],"prefix":"10.1055","volume":"230","author":[{"given":"Dilek","family":"Yavuzcan Ozturk","sequence":"additional","affiliation":[{"name":"Neonatology, University of Health Sciences, Istanbul,\n                    Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0727-4875","authenticated-orcid":false,"given":"Demet","family":"Oguz","sequence":"additional","affiliation":[{"name":"Neonatology, University of Health Sciences, Istanbul,\n                    Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Senay","family":"Coban","sequence":"additional","affiliation":[{"name":"Pediatric Cardiology, University of Health Sciences,\n                    Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erkut","family":"Ozturk","sequence":"additional","affiliation":[{"name":"Pediatric Cardiology, University of Health Sciences,\n                    Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2026,1,9]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"114","DOI":"10.21037\/tp.2019.04.06","article-title":"Acute therapy of newborns with critical congenital heart disease","volume":"8","author":"M Khalil","year":"2019","journal-title":"Transl Pediatr"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"1890","DOI":"10.1016\/S0735-1097(02)01886-7","article-title":"The incidence of congenital heart disease","volume":"39","author":"J I Hoffman","year":"2002","journal-title":"J Am Coll Cardiol"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"e0251255","DOI":"10.1371\/journal.pone.0251255","article-title":"Cerebral oxygen saturation and cerebrovascular instability in newborn infants\n                    with congenital heart disease compared to healthy controls","volume":"16","author":"N N Tran","year":"2021","journal-title":"PLoS One"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1055\/s-0034-1390349","article-title":"Necrotizing enterocolitis in infants with ductal-dependent congenital heart\n                    disease","volume":"32","author":"K C Becker","year":"2015","journal-title":"Am J 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Pediatr"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1016\/j.siny.2015.03.008","article-title":"Near-infrared spectroscopy: Applications in neonates","volume":"20","author":"B G Sood","year":"2015","journal-title":"Semin Fetal Neonatal Med"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1038\/s41372-021-00946-6","article-title":"Neonatal NIRS monitoring: Recommendations for data capture and review of\n                    analytics","volume":"41","author":"Z A Vesoulis","year":"2021","journal-title":"J Perinatol"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"1286","DOI":"10.1007\/s00246-014-0931-5","article-title":"Splanchnic near infrared spectroscopy and risk of necrotizing enterocolitis\n                    after neonatal heart surgery","volume":"35","author":"A G DeWitt","year":"2014","journal-title":"Pediatr Cardiol"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1161\/01.CIR.64.5.899","article-title":"Prostaglandin E1 infants with ductus arteriosus-dependent congenital heart\n                    disease","volume":"64","author":"M D Freed","year":"1981","journal-title":"Circulation"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1136\/archdischild-2017-313654","article-title":"Use of prostaglandins in duct-dependent congenital heart conditions","volume":"103","author":"Y Singh","year":"2018","journal-title":"Arch Dis Child Educ Pract Ed"}],"container-title":["Zeitschrift f\u00fcr Geburtshilfe und Neonatologie"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-2764-6472.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T23:29:06Z","timestamp":1781134146000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-2764-6472"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,9]]},"references-count":15,"journal-issue":{"issue":"03","published-online":{"date-parts":[[2026,6,5]]},"published-print":{"date-parts":[[2026,6]]}},"URL":"https:\/\/doi.org\/10.1055\/a-2764-6472","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["0948-2393","1439-1651"],"issn-type":[{"value":"0948-2393","type":"print"},{"value":"1439-1651","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1,9]]}}}