{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,24]],"date-time":"2026-04-24T23:33:44Z","timestamp":1777073624891,"version":"3.51.4"},"reference-count":91,"publisher":"Georg Thieme Verlag KG","issue":"02","license":[{"start":{"date-parts":[[2026,4,24]],"date-time":"2026-04-24T00:00:00Z","timestamp":1776988800000},"content-version":"vor","delay-in-days":23,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Tierarztl Prax Ausg G Grosstiere Nutztiere"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title>\n                  <jats:p>Q-Fieber, verursacht durch das obligat intrazellul\u00e4re Bakterium Coxiella burnetii, ist eine weltweit verbreitete Zoonose, bei der Wiederk\u00e4uer das wichtigste Reservoir darstellen. Die Mehrzahl der humanen Q-Fieber-F\u00e4lle in Deutschland sind auf kleine Wiederk\u00e4uer zur\u00fcckzuf\u00fchren. Epidemiologische Untersuchungen zeigen deutliche regionale Unterschiede in der Herdenpr\u00e4valenz, mit h\u00f6heren Q-Fieber-Nachweisraten in S\u00fcddeutschland, die insbesondere mit der asaisonalen Lammzeit zusammenh\u00e4ngen. Die Diagnostik am Tier beruht sowohl auf dem indirekten (v.\u2009a. ELISA) als auch direkten Erregernachweis (v.\u2009a. PCR), wobei beide Methoden keine eindeutige Aussage \u00fcber die Erregerfreiheit einzelner Tiere zulassen. Dies verdeutlicht auch die Notwendigkeit einer standardisierten \u00dcberwachung. Eine wirksame Therapie der Coxiellose bei Wiederk\u00e4uern steht derzeit nicht zur Verf\u00fcgung. Die Impfung mit einem inaktivierten Phase-I-Impfstoff ist daher die zentrale Ma\u00dfnahme zur Reduktion der Erregerausscheidung und Abortraten. Das europ\u00e4ische Tiergesundheitsrecht (Animal Health Law), betont die Verantwortung von Tierhaltenden, Tier\u00e4rztinnen und Tier\u00e4rzten sowie Beh\u00f6rden f\u00fcr Meldung, Pr\u00e4vention und Bek\u00e4mpfung der Coxiellose. Das interdisziplin\u00e4re Konsortium Q-GAPS hat dazu einen praxisorientierten Leitfaden unter anderem f\u00fcr Ausbruchsuntersuchungen und Risikokommunikation erarbeitet und weist darauf hin, dass eine effektive Pr\u00e4vention und Bek\u00e4mpfung des Q-Fiebers ein Zusammenspiel aus Impfung, Hygiene- und Umweltmanagement sowie einer engen Kooperation zwischen Veterin\u00e4r- und Humanmedizin im Sinne des One-Health-Ansatzes erfordert.<\/jats:p>","DOI":"10.1055\/a-2765-9826","type":"journal-article","created":{"date-parts":[[2026,4,24]],"date-time":"2026-04-24T22:33:58Z","timestamp":1777070038000},"page":"98-107","source":"Crossref","is-referenced-by-count":0,"title":["Coxiella burnetii bei kleinen Wiederk\u00e4uern \u2013 Umgang mit dem Zoonoseerreger"],"prefix":"10.1055","volume":"54","author":[{"given":"Martin","family":"Runge","sequence":"additional","affiliation":[{"name":"Lebensmittel- und Veterin\u00e4rinstitut Braunschweig\/Hannover, Nieders\u00e4chsisches Landesamt f\u00fcr Verbraucherschutz und Lebensmittelsicherheit (LAVES), Hannover"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fenja","family":"Winter","sequence":"additional","affiliation":[{"name":"Hannover"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Louise","family":"Herms","sequence":"additional","affiliation":[{"name":"Lebensmittel- und Veterin\u00e4rinstitut Braunschweig\/Hannover, Nieders\u00e4chsisches Landesamt f\u00fcr Verbraucherschutz und Lebensmittelsicherheit (LAVES), Hannover"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katja","family":"Mertens-Scholz","sequence":"additional","affiliation":[{"name":"Nationales Referenzlabor f\u00fcr Q-Fieber, Institut f\u00fcr bakterielle Infektionen und Zoonosen, Friedrich-Loeffler-Institut, Jena"},{"name":"Institut f\u00fcr Infektionsmedizin und Krankenhaushygiene, Universit\u00e4tsklinikum Jena, Jena"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Silke F.","family":"Fischer","sequence":"additional","affiliation":[{"name":"Konsiliarlabor f\u00fcr Coxiella burnetii, Landesgesundheitsamt Baden-W\u00fcrttemberg, Stuttgart"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Benjamin U.","family":"Bauer","sequence":"additional","affiliation":[{"name":"Institut f\u00fcr Immunologie, Friedrich-Loeffler-Institut, Greifswald \u2013 Insel Riems"},{"name":"Klinik f\u00fcr kleine Klauentiere und forensische Medizin und Ambulatorische Klinik, Stiftung Tier\u00e4rztliche Hochschule Hannover"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2026,4,24]]},"reference":[{"key":"ref2","doi-asserted-by":"publisher","first-page":"423","DOI":"10.1051\/vetres:2003017","article-title":"Experimental Coxiella burnetii infection in pregnant goats: excretion routes","volume":"34","author":"N Arricau-Bouvery","year":"2003","journal-title":"Vet 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