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Comparative metabolic profiling revealed\n                    both common and inhibitor-specific metabolic alterations. Pathway enrichment\n                    analysis identified significant downregulation in starch and sucrose metabolism,\n                    nucleotide sugar metabolism and sphingolipid metabolism. These results offered\n                    insights to guide the development of treatment strategies for overcoming the\n                    drug resistance in chronic myelogenous leukemia as well as managing the\n                    associated toxicities.<\/jats:p>","DOI":"10.1055\/a-2769-1965","type":"journal-article","created":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T00:15:53Z","timestamp":1769127353000},"page":"99-101","source":"Crossref","is-referenced-by-count":0,"title":["Treatment of K562 Cells with ABL Kinase Inhibitors Reveals\n                    Differential Metabolic Profiles"],"prefix":"10.1055","volume":"76","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-0663-1130","authenticated-orcid":false,"given":"Pranay","family":"Renukuntla","sequence":"additional","affiliation":[{"name":"Department of Analytical and Structural Chemistry, CSIR - Indian\n                    Institute of Chemical Technology, 500007, Hyderabad, India"},{"name":"Academy of Scientific and Innovative Research (AcSIR), Ghaziabad,\n                    201002, Uttar Pradesh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sai Charitha","family":"Mullaguri","sequence":"additional","affiliation":[{"name":"Molecular Medicine and Therapeutics Laboratory, CPMB, Osmania\n                    University, 500007, Hyderabad, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Divya","family":"Presingu","sequence":"additional","affiliation":[{"name":"Department of Analytical and Structural Chemistry, CSIR - 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