{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T11:14:57Z","timestamp":1792062897327,"version":"4.4.0"},"reference-count":10,"publisher":"Georg Thieme Verlag KG","issue":"05","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Zentralbl Chir"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title>\n                  <jats:p>Die Thoracoflo-Hypridprothese wurde entwickelt, um thorakoabdominelle Aortenpathologien bei einem selektiven Patientengut ohne Thorakotomie, thorakale Aortenklemmung und Herz-Lungen-Maschine (HLM) zu versorgen. Im Manuskript werden die Selektionskriterien f\u00fcr Behandlung der Patient*innen sowie die Tipps und Tricks nach den ersten klinischen Erfahrungen zusammengefasst.<\/jats:p>\n                  <jats:p>Seit September 2021 wurden weltweit in Zentren mit hoher Expertise in endovaskul\u00e4rer und offen operativer Versorgung thorakoabdomineller Aortenpathologien insgesamt 50 Patient*innen mit der Thoracoflo-Prothese versorgt. Alle Patient*innen wurden in einem interdisziplin\u00e4ren Board selektioniert. Eine konventionelle offene oder alleinige endovaskul\u00e4re Versorgung war aufgrund anatomischer Gegebenheiten oder Begleiterkrankungen nicht m\u00f6glich oder zu riskant. Vor allen Engriffen wurde ein Simulatortraining mit dem Operationsteam durchgef\u00fchrt und der operative Eingriff wurde von einem Proktor begleitet. Alle Eingriffe wurden bez. der OP-Technik und intraprozeduraler Pitfalls analysiert, und es wurden entsprechend Empfehlungen im Sinne von Tipps und Tricks erarbeitet.<\/jats:p>\n                  <jats:p>Voraussetzung f\u00fcr die Implantation ist eine sichere Landezone in der thorakalen Aorta, die auch mittels TEVAR erreicht werden kann, und die M\u00f6glichkeit der retrograden viszeralen Perfusion (sichere Versorgung der Viszeralarterien bei Dissektion, keine hohe Thrombuslast). Die Thoracoflo-Hybridprothese konnte bei 49 von 50 Patienten erfolgreich implantiert werden, bei einem Patienten musste intraoperativ eine Konversion mit Thorakolaparotomie und Herz-Lungen-Maschine erfolgen. Im Rahmen des Debriefings wurden alle Eingriffe rekapituliert und entsprechende Empfehlungen zusammengefasst.<\/jats:p>\n                  <jats:p>Die Thoracoflo-Hybridprothese bietet f\u00fcr komplexe thorakoabdominelle Aortenpathologien eine Therapieoption, sofern die perioperativen Voraussetzungen ber\u00fccksichtigt werden. Hierbei sollte auf eine optimale Patientenselektionierung und die korrekte Indikationsstellung geachtet werden.<\/jats:p>","DOI":"10.1055\/a-2773-6571","type":"journal-article","created":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T00:20:54Z","timestamp":1770769254000},"page":"439-443","source":"Crossref","is-referenced-by-count":1,"title":["Die Thoracoflo-Hybridprothese zum thorakoabdominellen Aortenersatz \u2013 Tipps und Tricks nach ersten klinischen Erfahrungen"],"prefix":"10.1055","volume":"151","author":[{"given":"Sabine","family":"Wipper","sequence":"additional","affiliation":[{"name":"Medizinische Universit\u00e4t Innsbruck, Tyrol, \u00d6sterreich","place":["Innsbruck"],"department":["Universit\u00e4tsklinik f\u00fcr Gef\u00e4\u00dfchirurgie"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7200-4145","authenticated-orcid":false,"given":"Florian K.","family":"Enzmann","sequence":"additional","affiliation":[{"name":"Medizinische Universit\u00e4t Innsbruck, Tyrol, \u00d6sterreich","place":["Innsbruck"],"department":["Universit\u00e4tsklinik f\u00fcr Gef\u00e4\u00dfchirurgie"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Wippel","sequence":"additional","affiliation":[{"name":"Medizinische Universit\u00e4t Innsbruck, Tyrol, \u00d6sterreich","place":["Innsbruck"],"department":["Universit\u00e4tsklinik f\u00fcr Gef\u00e4\u00dfchirurgie"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julia","family":"Dumfarth","sequence":"additional","affiliation":[{"name":"Medizinische Universit\u00e4t Innsbruck, Tyrol, \u00d6sterreich","place":["Innsbruck"],"department":["Universit\u00e4tsklinik f\u00fcr Gef\u00e4\u00dfchirurgie"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tilo","family":"K\u00f6lbel","sequence":"additional","affiliation":[{"name":"Universit\u00e4tsklinikum Hamburg-Eppendorf, Tyrol, Deutschland","place":["Hamburg"],"department":["Klink und Poliklinik f\u00fcr Gef\u00e4\u00dfmedizin, Deutsches Aortenzentrum"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sebastian","family":"Debus","sequence":"additional","affiliation":[{"name":"Universit\u00e4tsklinikum Hamburg-Eppendorf, Tyrol, Deutschland","place":["Hamburg"],"department":["Klink und Poliklinik f\u00fcr Gef\u00e4\u00dfmedizin, Deutsches Aortenzentrum"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2026,2,10]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1510\/mmcts.2006.001990","article-title":"The frozen elephant trunk technique","volume":"2007","author":"MA Pichlmaier","year":"2007","journal-title":"Multimed Man Cardiothorac Surg"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"406","DOI":"10.1093\/ejcts\/ezs296","article-title":"Total aortic arch replacement with a novel 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