{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,24]],"date-time":"2026-04-24T23:41:25Z","timestamp":1777074085727,"version":"3.51.4"},"reference-count":29,"publisher":"Georg Thieme Verlag KG","issue":"02","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Tierarztl Prax Ausg K Kleintiere Heimtiere"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title>\n                  <jats:p>Die Enzephalitozoonose ist eine bei Kaninchen weit verbreitete Krankheit, die zudem als potenzielle Zoonose von Bedeutung ist. Ziel der Untersuchung war die Analyse der Encephalitozoonose in Bezug auf die Diagnose und Behandlung anhand einer retrospektiven Auswertung von Patientendaten.<\/jats:p>\n                  <jats:p>107 F\u00e4lle von Kaninchen mit Verdachtsdiagnose Encephalitozoonose, die zwischen 2013 und 2022 in einer universit\u00e4ren Klinik vorgestellt wurden, wurden retrospektiv ausgewertet. Die Aufarbeitung der F\u00e4lle erfolgte bez\u00fcglich Form der Encephalitozoonose, Haltung, F\u00fctterung, Diagnostik, Therapie und Outcome.<\/jats:p>\n                  <jats:p>Die Haltungsformen \u2013 Innenhaltung versus Au\u00dfenhaltung, Einzelhaltung versus Gruppenhaltung \u2013 sowie die k\u00fcrzlich erfolgte Integration eines Tiers in den Bestand ergaben keinen statistischen Effekt als pr\u00e4disponierende Faktoren. Klinisch manifestierte sich die Encephalitozoonose bei 63,6% (n=68) der F\u00e4lle im zentralen Nervensystem. Das Durchschnittsalter der Tiere mit okul\u00e4rer Form war mit 23,7 Monaten signifikant niedriger (p&lt;0,001) und dasjenige der Tiere mit renaler Form mit einem Mittelwert von 71,4 Monaten h\u00f6her als das Durchschnittsalter der gesamten untersuchten Population erkrankter Tiere. Beim Vergleich des Outcomes von 84 Kaninchen wiesen 29,8% (n=25) eine Besserung auf, eine Stabilisierung wurde bei 44,0% (n=37) erreicht und 28,2% (n=22) verstarben oder mussten euthanasiert werden. Der IgG-Titer war mit&gt;1:5120 bei den verstorbenen beziehungsweise euthanasierten Kaninchen mit 50,0% (n=6) deutlich h\u00e4ufiger stark erh\u00f6ht.<\/jats:p>\n                  <jats:p>Die vorliegende Untersuchung ergab keinen Einfluss von Haltungsparametern auf die Encephalitozoonose. Es bestand ein Zusammenhang zwischen Alter und Krankheitsform. Der Nachweis von Antik\u00f6rpern spielte in der Diagnostik eine zentrale Rolle, lie\u00df jedoch nur eine Verdachtsdiagnose zu. Therapeutisch kamen Fendendazol, Analgesie, Entz\u00fcndungshemmer sowie unterst\u00fctzende Ma\u00dfnahmen zum Einsatz. Solche Ma\u00dfnahmen umfassten bei der zentralnerv\u00f6sen Form eine ruhige und stressfreie Haltung sowie Physiotherapie und bei der renalen Form das Sicherstellen der Hydratation. In rund 70% der F\u00e4lle wurde eine Besserung oder Stabilisierung des Zustandes erreicht.<\/jats:p>","DOI":"10.1055\/a-2773-7850","type":"journal-article","created":{"date-parts":[[2026,4,24]],"date-time":"2026-04-24T23:07:11Z","timestamp":1777072031000},"page":"70-79","source":"Crossref","is-referenced-by-count":0,"title":["Encephalitozoonose bei Kaninchen \u2013 eine retrospektive Auswertung von Patientendaten"],"prefix":"10.1055","volume":"54","author":[{"given":"Jean-Michel","family":"Hatt","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Zoo-, Heim- und Wildtiere, Vetsuisse-Fakult\u00e4t, Universit\u00e4t Z\u00fcrich, Schweiz"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nathalie","family":"Spahni","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Zoo-, Heim- und Wildtiere, Vetsuisse-Fakult\u00e4t, Universit\u00e4t Z\u00fcrich, Schweiz"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manuela Schnyder","family":"Gasparoli","sequence":"additional","affiliation":[{"name":"Institut f\u00fcr Parasitologie, Vetsuisse-Fakult\u00e4t, Universit\u00e4t Z\u00fcrich, Schweiz"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2026,4,24]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"1486","DOI":"10.3390\/pathogens11121486","article-title":"A Review of Encephalitozoon cuniculi in domestic rabbits (Oryctolagus cuniculus) \u2013 biology, clinical signs, diagnostic techniques, treatment, and prevention","volume":"11","author":"A-A Dobo\u0219i","year":"2022","journal-title":"Pathogens"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1159\/000060363","volume-title":"Petry F, Hrsg. 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