{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,24]],"date-time":"2026-04-24T23:41:26Z","timestamp":1777074086028,"version":"3.51.4"},"reference-count":34,"publisher":"Georg Thieme Verlag KG","issue":"02","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Tierarztl Prax Ausg K Kleintiere Heimtiere"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title>\n                  <jats:p>Ein 5 Jahre altes Zwergkaninchen (Oryctolagus cuniculus) mit einem K\u00f6rpergewicht von 2,46\u2009kg wurde aufgrund akuter Inappetenz, Apathie und Diarrhoe vorgestellt. Das Tier lebte mit einem Partnertier in einem Au\u00dfengehege mit nat\u00fcrlichem Bodengrund und einem unterirdischen Tunnelsystem. Die klinische Allgemeinuntersuchung ergab eine hochgradige Apathie, Hypothermie (36,3\u00b0C) sowie eine verst\u00e4rkte abdominale Atmung. Labordiagnostisch wurden eine nicht-regenerative An\u00e4mie sowie eine heterophile und monozyt\u00e4re Leukozytose festgestellt. R\u00f6ntgenologisch waren eine vergr\u00f6\u00dferte Leber sowie ein peritonealer Detailverlust erkennbar. Als Hauptbefunde konnten im abdominalen Ultraschall neben einer Vergr\u00f6\u00dferung von Leber und Milz mehrere hypoechogene Rundschatten in der Leber sowie deutlich vergr\u00f6\u00dferte mesenteriale Lymphknoten und freie Fl\u00fcssigkeit nachgewiesen werden. Zudem waren mehrere Umfangsvermehrungen in den Metren und ein fokaler Niereninfarkt im Bereich des kraniodorsalen rechten Nierenkortex auff\u00e4llig. In der Computertomografie wurden neben den bereits im Ultraschall festgestellten Ver\u00e4nderungen generalisierte Verdickungen der Dickdarmw\u00e4nde nachgewiesen. Aufgrund des schlechten Allgemeinbefindens und der Befunde wurde das Tier auf Wunsch des Besitzers euthanasiert und pathologisch untersucht. Hauptbefunde waren neben einer Lymphadenomegalie multifokaler Darmlymphknoten multiple nekrotisierende Entz\u00fcndungen in Milz, Leber und Knochenmark. Aus der Milz konnte Yersinia pseudotuberculosis isoliert und die Diagnose Pseudotuberkulose gestellt werden. Diese potenzielle Zoonose wurde bisher nur in einem weiteren Fallbericht bei Heimtierkaninchen in der Fachliteratur dokumentiert und sollte differenzialdiagnostisch bei schwerer Allgemeinerkrankung von Kaninchen in Au\u00dfenhaltung ber\u00fccksichtigt werden.<\/jats:p>","DOI":"10.1055\/a-2773-8185","type":"journal-article","created":{"date-parts":[[2026,4,24]],"date-time":"2026-04-24T23:07:11Z","timestamp":1777072031000},"page":"117-123","source":"Crossref","is-referenced-by-count":0,"title":["Pseudotuberkulose verursacht durch Yersinia pseudotuberculosis bei einem Heimtierkaninchen (Oryctolagus cuniculus)"],"prefix":"10.1055","volume":"54","author":[{"given":"Nico","family":"Habeck","sequence":"additional","affiliation":[{"name":"Klein- und Heimtierklinik, Abteilung Kleins\u00e4uger, V\u00f6gel, Reptilien, Freie Universit\u00e4t Berlin"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert","family":"Klopfleisch","sequence":"additional","affiliation":[{"name":"Institut f\u00fcr Tierpathologie, Freie Universit\u00e4t Berlin"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Florian","family":"Bartenschlager","sequence":"additional","affiliation":[{"name":"Institut f\u00fcr Tierpathologie, Freie Universit\u00e4t Berlin"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antina","family":"L\u00fcbke-Becker","sequence":"additional","affiliation":[{"name":"Institut f\u00fcr Mikrobiologie und Tierseuchen, Freie Universit\u00e4t Berlin"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kerstin","family":"von P\u00fcckler","sequence":"additional","affiliation":[{"name":"Abteilung Radiologie, Klinik f\u00fcr Kleintiere, Justus-Liebig-Universit\u00e4t Gie\u00dfen"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kerstin","family":"M\u00fcller","sequence":"additional","affiliation":[{"name":"Klein- und Heimtierklinik, Abteilung Kleins\u00e4uger, V\u00f6gel, Reptilien, Freie Universit\u00e4t Berlin"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2026,4,24]]},"reference":[{"key":"ref1","volume-title":"Barthold SW, Griffey SM, Percy DH, Hrsg. Pathology of Laboratory Rodents and Rabbits. 4. Aufl","author":"S W Barthold","year":"2016"},{"key":"ref2","doi-asserted-by":"crossref","DOI":"10.1002\/9780470693780","volume-title":"Richardson VCG, Hrsg. Rabbits: Health, Husbandry and Diseases","author":"VC G Richardson","year":"2000"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"161","DOI":"10.3390\/vetsci12020161","article-title":"Bruins-van Sonsbeek LGR, Stumpel JBG et al. Yersinia pseudotuberculosis in non-domesticated mammals and birds in captivity","volume":"12","author":"R A Nederlof","year":"2025","journal-title":"Vet Sci"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"516","DOI":"10.3390\/microorganisms13030516","article-title":"Occurrence and monitoring of the zoonotic pathogen Yersinia pseudotuberculosis in various zoo animal species","volume":"13","author":"L L Riede","year":"2025","journal-title":"Microorganisms"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"285","DOI":"10.1016\/j.apjtm.2017.03.008","article-title":"Experimental infection with Yersinia pseudotuberculosis in european brown hare (Lepus europaeus, Pallas)","volume":"10","author":"F Fratini","year":"2017","journal-title":"Asian Pac J Trop Med"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"235","DOI":"10.1055\/b000000531","volume-title":"Selbitz H-J, Truyen U, Valentin-Weigand P, Hrsg. Tiermedizinische Mikrobiologie, Infektions- und Seuchenlehre. 11. Aufl","author":"L H Wieler","year":"2023"},{"key":"ref8","volume-title":"Suckow MA, Stevens KA, Wilson RP, Hrsg. The Laboratory Rabbit, Guinea Pig, Hamster, and other Rodents","author":"D DeLong","year":"2012"},{"key":"ref9","volume-title":"Quesenberry KE, Orcutt CJ, Mans C et al., Hrsg. Ferrets, Rabbits, and Rodents: Clinical Medicine and Surgery. 3. Aufl","author":"M A Mitchell","year":"2021"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"182","DOI":"10.1053\/j.jepm.2018.05.006","article-title":"Antemortem diagnosis and surgical management of splenitis due to Yersinia pseudotuberculosis infection in a pet rabbit (Oryctolagus cuniculus)","volume":"29","author":"L Chassang","year":"2019","journal-title":"J Exot Pet Med"},{"key":"ref11","volume-title":"Gabrisch K, Zwart P, Fehr M et al., Hrsg. Krankheiten der Heimtiere. 8. Aufl","author":"K M\u00fcller","year":"2015"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2021.634289","article-title":"Birds kept in the german zoo \u201cTierpark Berlin\u201d are a common source for polyvalent Yersinia pseudotuberculosis phages","volume":"12","author":"J A Hammerl","year":"2022","journal-title":"Front Microbiol"},{"key":"ref13","first-page":"1251","article-title":"Tularemia, Plague, Yersiniosis, and Tyzzer\u2019s Disease in wild rodents and lagomorphs in Canada: a review","volume":"50","author":"G Wobeser","year":"2009","journal-title":"Can Vet J"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"393","DOI":"10.1080\/03079459994669","article-title":"Visceral lesions caused by Yersinia pseudotuberculosis, serotype II, in different species of bird","volume":"28","author":"S C Cork","year":"1999","journal-title":"Avian Pathol"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.3389\/fvets.2023.1261925","article-title":"First isolation of Yersinia pseudotuberculosis from the blood of a cat","volume":"10","author":"R Scarpellini","year":"2024","journal-title":"Front Vet Sci"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1177\/2055116919853644","article-title":"Successful treatment of Yersinia pseudotuberculosis hepatitis in a cat presenting with neurological abnormalities","volume":"5","author":"D Thompson","year":"2019","journal-title":"J Feline Med Surg Open Rep"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"54","DOI":"10.3390\/pathogens13010054","article-title":"Enteropathogenic Yersinia with public health relevance found in dogs and cats in Finland","volume":"13","author":"M Fredriksson-Ahomaa","year":"2024","journal-title":"Pathogens"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"616","DOI":"10.1128\/jcm.19.5.616-622.1984","article-title":"Prospective systematic study of Yersinia spp. in dogs","volume":"19","author":"H Fukushima","year":"1984","journal-title":"J Clin Microbiol"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"641","DOI":"10.1177\/1040638715596035","article-title":"Yersiniosis due to infection by Yersinia pseudotuberculosis 4b in captive meerkats (Suricata suricatta) in Japan","volume":"27","author":"S Nakamura","year":"2015","journal-title":"J Vet Diagn Invest"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"203","DOI":"10.1046\/j.1439-0450.2001.00448.x","article-title":"Isolation of pathogenic Yersiniae from wild animals in Bulgaria","volume":"48","author":"S Nikolova","year":"2001","journal-title":"J Vet Med B"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"202","DOI":"10.7589\/0090-3558-38.1.202","article-title":"Occurrence of Yersiniosis and Listeriosis in wild boars in Japan","volume":"38","author":"H Hayashidani","year":"2002","journal-title":"J Wildl Dis"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"584","DOI":"10.1128\/jcm.26.3.584-585.1988","article-title":"Yersinia pseudotuberculosis infection contracted through water contaminated by a wild animal","volume":"26","author":"H Fukushima","year":"1988","journal-title":"J Clin Microbiol"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2019.01049","article-title":"Genomic epidemiology and phenotyping reveal on-farm persistence and cold adaptation of raw milk outbreak-associated Yersinia pseudotuberculosis","volume":"10","author":"H Castro","year":"2019","journal-title":"Front Microbiol"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.2903\/j.efsa.2024.9106","article-title":"The European Union one health 2023 zoonoses report","volume":"22","author":"European Food Safety Authority (EFSA), European Centre for Disease Prevention and Control (ECDC)","year":"2024","journal-title":"EFSA J"},{"key":"ref25","volume-title":"Baumg\u00e4rtner W, Gruber A, Hrsg. Spezielle Pathologie f\u00fcr die Tiermedizin. 2. Aufl","author":"A Gruber","year":"2020"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.00654-18","article-title":"Yersinia pseudotuberculosis exploits cd209 receptors for promoting host dissemination and infection","volume":"87","author":"Y-X He","year":"2018","journal-title":"Infect Immun"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"280","DOI":"10.1046\/j.1439-0450.2003.00679.x","article-title":"Experimental infections with wild and mutant Yersinia pseudotuberculosis strains in rabbits","volume":"50","author":"H Najdenski","year":"2003","journal-title":"J Vet Med B"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"656","DOI":"10.1136\/vr.104472","article-title":"Anaemia in pet rabbits: causes, severity and reticulocyte response","volume":"181","author":"A Dettweiler","year":"2017","journal-title":"Vet Rec"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"404","DOI":"10.1016\/B978-1-4557-7397-8.00042-6","volume-title":"Miller RE, Fowler ME, Agnew M, Hrsg. Fowler\u2019s Zoo and Wild Animal Medicine. 8. Aufl","author":"E Yarto-Jaramillo","year":"2015"},{"key":"ref30","first-page":"531","article-title":"Yersinia pestis (Plague) and other Yersinioses","author":"J E Sykes","year":"2014","journal-title":"Can Feline Infect Dis"},{"key":"ref31","volume-title":"M\u00fcller K, Hrsg. HeimtierSkills: Praxisleitfaden zu Diagnose und Therapie bei kleinen Heimtieren","author":"K M\u00fcller","year":"2017"},{"key":"ref33","doi-asserted-by":"publisher","first-page":"2411","DOI":"10.5897\/AJB2007.000-2378","article-title":"Experimental Yersinia pseudotuberculosis enteritis in laboratory animals","volume":"6","author":"AE J Okwori","year":"2007","journal-title":"Afr J Biotechnol"},{"key":"ref35","doi-asserted-by":"publisher","first-page":"656","DOI":"10.1016\/j.jfma.2011.06.020","article-title":"The first imported human case of Yersinia pseudotuberculosis serotype o1 septicemia presents with acute appendicitis-like syndrome in Taiwan","volume":"113","author":"C-H Lai","year":"2014","journal-title":"J Formos Med Assoc"},{"key":"ref36","doi-asserted-by":"publisher","first-page":"766","DOI":"10.1086\/381766","article-title":"A widespread outbreak of Yersinia pseudotuberculosis o:3 infection from iceberg lettuce","volume":"189","author":"J P Nuorti","year":"2004","journal-title":"J Infect Dis"},{"key":"ref37","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.00675-18","article-title":"Yersinia pseudotuberculosis prevalence and diversity in wild boars in northeast Germany","volume":"84","author":"M Reinhardt","year":"2018","journal-title":"Appl Environ Microbiol"}],"container-title":["Tier\u00e4rztliche Praxis Ausgabe K: Kleintiere \/ Heimtiere"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-2773-8185.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,24]],"date-time":"2026-04-24T23:07:25Z","timestamp":1777072045000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-2773-8185"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4]]},"references-count":34,"journal-issue":{"issue":"02","published-online":{"date-parts":[[2026,2,11]]},"published-print":{"date-parts":[[2026,4]]}},"URL":"https:\/\/doi.org\/10.1055\/a-2773-8185","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["1434-1239","2567-5842"],"issn-type":[{"value":"1434-1239","type":"print"},{"value":"2567-5842","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4]]}}}