{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,6]],"date-time":"2026-02-06T13:22:38Z","timestamp":1770384158060,"version":"3.49.0"},"reference-count":8,"publisher":"Georg Thieme Verlag KG","issue":"05\/06","license":[{"start":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T00:00:00Z","timestamp":1767916800000},"content-version":"vor","delay-in-days":100,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Aorta (Stamford)"],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Two pregnant siblings presented with thoracic aortic dissection during the second trimester. A pathogenic MYH11 was identified following the first sibling's diagnosis. The second sibling, previously known to be at risk but lost to follow-up, reengaged during pregnancy, tested positive for the familial variant, and dissected before her initial evaluation. This case highlights the importance of genetic diagnosis, surveillance, and multidisciplinary care in managing heritable thoracic aortic disease during pregnancy.<\/jats:p>","DOI":"10.1055\/a-2774-6679","type":"journal-article","created":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T23:52:18Z","timestamp":1768002738000},"page":"101-104","source":"Crossref","is-referenced-by-count":0,"title":["Management of Myosin Heavy Chain 11\u2013Associated Familial Thoracic Aortic Aneurysm and Dissection During Pregnancy in Two Siblings"],"prefix":"10.1055","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-8861-5609","authenticated-orcid":false,"given":"Anthony Talea","family":"Pohahau","sequence":"additional","affiliation":[{"name":"Division of Vascular Surgery, Department of Surgery, Oregon Health and Science University, Portland, Oregon, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ishaq J.","family":"Wadiwala","sequence":"additional","affiliation":[{"name":"Division of Vascular Surgery, Department of Surgery, Oregon Health and Science University, Portland, Oregon, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lidija","family":"McGrath","sequence":"additional","affiliation":[{"name":"Knight Cardiovascular Institute, Section of Adult Congenital Heart Disease, Oregon Health and Science University, Portland, Oregon, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amy","family":"Hermesch","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Oregon Health and Science University, Portland, Oregon, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sherene","family":"Shalhub","sequence":"additional","affiliation":[{"name":"Division of Vascular Surgery, Department of Surgery, Oregon Health and Science University, Portland, Oregon, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Castigliano M.","family":"Bhamidipati","sequence":"additional","affiliation":[{"name":"Division of Cardiothoracic Surgery, Department of Surgery, Oregon Health and Science University, Portland, Oregon, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julie W.","family":"Doberne","sequence":"additional","affiliation":[{"name":"Division of Cardiothoracic Surgery, Department of Surgery, Oregon Health and Science University, Portland, Oregon, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2026,1,9]]},"reference":[{"issue":"24","key":"ref1","doi-asserted-by":"crossref","first-page":"e334","DOI":"10.1161\/CIR.0000000000001106","article-title":"2022 ACC\/AHA Guideline for the diagnosis and management of aortic disease: a report of the American Heart Association\/American College of Cardiology Joint Committee on clinical 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patient","volume":"32","author":"A Raghuram","year":"2023","journal-title":"J Stroke Cerebrovasc Dis"},{"issue":"01","key":"ref8","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1186\/s12920-024-01908-5","article-title":"Complex genotype-phenotype correlation of MYH11: new insights from monozygotic twins with highly variable expressivity and outcomes","volume":"17","author":"X Wei","year":"2024","journal-title":"BMC Med Genomics"}],"container-title":["AORTA"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-2774-6679.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,5]],"date-time":"2026-02-05T23:38:31Z","timestamp":1770334711000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-2774-6679"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10]]},"references-count":8,"journal-issue":{"issue":"05\/06","published-online":{"date-parts":[[2026,2,5]]},"published-print":{"date-parts":[[2025,10]]}},"URL":"https:\/\/doi.org\/10.1055\/a-2774-6679","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["2325-4637"],"issn-type":[{"value":"2325-4637","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,10]]}}}